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Condition: Thrombosis
Procedure: Angioplasty
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Total 986 results found since Jan 2013.
Prognostic Impact of Renal Dysfunction at 1-Year Follow-Up on Clinical Outcomes After Percutaneous Coronary Intervention
CONCLUSION: Persistent and new-onset renal dysfunction at 1-year follow-up were associated with unfavorable outcomes in patients with CAD who underwent PCI.PMID:36123047 | DOI:10.5551/jat.63746
Source: Journal of Atherosclerosis and Thrombosis - September 19, 2022 Category: Cardiology Authors: Tetsuya Takahashi Tetsu Watanabe Tomonori Aono Yoichiro Otaki Masahiro Wanezaki Satoshi Nishiyama Daisuke Kutsuzawa Shigehiko Kato Harutoshi Tamura Takanori Arimoto Hiroki Takahashi Masafumi Watanabe Source Type: research
Anti-Atherosclerotic Therapies: Milestones, Challenges, and Emerging Innovations
Mol Ther. 2022 Sep 4:S1525-0016(22)00553-6. doi: 10.1016/j.ymthe.2022.08.024. Online ahead of print.ABSTRACTAtherosclerosis is the main underlying pathology for many cardiovascular diseases (CVD) which are the leading cause of death globally and represent a serious health crisis. Atherosclerosis is a chronic condition that can lead to myocardial infarction, ischemic cardiomyopathy, stroke, and peripheral arterial disease. Elevated plasma lipids, hypertension, and high glucose are the major risk factors for developing atherosclerotic plaques. To date, most pharmacological therapies aim to control these risk factors but do n...
Source: Atherosclerosis - September 6, 2022 Category: Cardiology Authors: Isabella Hetherington Hana Totary-Jain Source Type: research
A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes Following Acute Myocardial Infarction
CONCLUSIONS: In patients with recent acute MI, 3 doses of asundexian, when added to aspirin plus a P2Y12 inhibitor, resulted in dose-dependent, near-complete inhibition of FXIa activity without a significant increase in bleeding and a low rate of ischemic events. These data support the investigation of asundexian at a dose of 50 mg daily in an adequately powered clinical trial of patients following acute MI.PMID:36030390 | DOI:10.1161/CIRCULATIONAHA.122.061612
Source: Circulation - August 28, 2022 Category: Cardiology Authors: Sunil V Rao Bodo Kirsch Deepak L Bhatt Andrzej Budaj Rosa Coppolecchia John Eikelboom Stefan K James W Schuyler Jones Bela Merkely Lars Keller Renicus S Hermanides Gianluca Campo Jos é Luis Ferreiro Taro Shibasaki Hardi Mundl John H Alexander Source Type: research
New permanent bundle-branch block and long-term prognosis of patients with new onset ST-elevation myocardial infarction who underwent percutaneous coronary intervention
Conclusion: New onset permanent RBBB in patients with new onset STEMI who underwent PCI may be correlated independently with increased risk of poor long-term prognosis.
Source: Frontiers in Physiology - August 22, 2022 Category: Physiology Source Type: research
Adverse Impact of Peri-Procedural Stroke in Patients Who Underwent Percutaneous Coronary Intervention
Peri-procedural stroke (PPS) is an important complication in patients who underwent percutaneous coronary intervention (PCI). The extent to which PPS impacts mortality and outcomes remains to be defined. Consecutive patients who underwent PCI enrolled in the Victorian Cardiac Outcomes Registry (2014 to 2018) were categorized into PPS and no PPS groups. The primary outcome was 30-day major adverse cardiovascular events (MACEs) (composite of mortality, myocardial infarction, stent thrombosis, and unplanned revascularization).
Source: The American Journal of Cardiology - August 20, 2022 Category: Cardiology Authors: Noah Z. Wexler, Sara Vogrin, Angela L. Brennan, Samer Noaman, Omar Al-Mukhtar, Kawa Haji, Jason E. Bloom, Diem T. Dinh, Wayne C. Zheng, James A. Shaw, Stephen J. Duffy, Jeffrey Lefkovits, Christopher M. Reid, Dion Stub, David M. Kaye, Nicholas Cox, Willia Source Type: research
Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer
Cell Mol Neurobiol. 2022 Aug 11:1-12. doi: 10.1007/s10571-022-01260-1. Online ahead of print.ABSTRACTThe most important predictors for outcomes after ischemic stroke, that is, for health deterioration and death, are chronological age and stroke severity; gender, genetics and lifestyle/environmental factors also play a role. Of all these, only the latter can be influenced after the event. Recurrent stroke may be prevented by antiaggregant/anticoagulant therapy, angioplasty of high-grade stenoses, and treatment of cardiovascular risk factors. Blood cell composition and protein biomarkers such as C-reactive protein or interle...
Source: Cellular and Molecular Neurobiology - August 11, 2022 Category: Cytology Authors: Georg Fuellen Uwe Walter Larissa Henze Jan B öhmert Daniel Palmer Soyoung Lee Clemens A Schmitt Henrik Rudolf Axel Kowald Source Type: research
Paradoxical Long-Term Impact Between Serum Apolipoprotein E and High-Density Lipoprotein Cholesterol in Patients Undergoing Percutaneous Coronary Intervention
CONCLUSIONS: Serum ApoE levels may have a paradoxical impact on the future cardiovascular risk depending on the HDL-C status in patients with CAD.PMID:35934781 | DOI:10.5551/jat.63535
Source: Journal of Atherosclerosis and Thrombosis - August 7, 2022 Category: Cardiology Authors: Tatsuya Fukase Tomotaka Dohi Ryota Nishio Mitsuhiro Takeuchi Norihito Takahashi Yuichi Chikata Hirohisa Endo Shinichiro Doi Hiroki Nishiyama Iwao Okai Hiroshi Iwata Shinya Okazaki Katsumi Miyauchi Hiroyuki Daida Tohru Minamino Source Type: research
