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E-189 Outcomes of tenecteplase versus alteplase after mechanical thrombectomy in a multiethnic stroke consortium registry
ConclusionIn this prospective, multi-center stroke consortium study, IV TNK in comparison to tPA prior to MT for ischemic stroke resulted in non-inferior outcomes related to angiographic reperfusion and functional status at discharge. These findings compliment the current literature and include a large Hispanic US cohort. Further analysis will include expansion of contributing centers and use of propensity scoring.Abstract E-189 Table 1 and 2Disclosures M. Gaub: None. D. Ramaswamy: None. A. Cardentey: None. S. Bandela: None. G. Gealogo: None. J. Mascitelli: None. F. Al Saiegh: None. L. Birnbaum: 2; C; Rapid AI, Imperative Care.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Gaub, M., Ramaswamy, D., Cardentey, A., Bandela, S., Gealogo, G., Mascitelli, J., Al Saiegh, F., Birnbaum, L. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-035 Endovascular treatment of cerebral venous thrombosis involving the deep venous system
ConclusionsAlthough deep venous involvement of CVT is uncommon, these patients are at risk of quickly becoming critically ill with an elevated rate of death or dependency. Although these patients may develop stroke, hemorrhage, or neurologic decline prompting consideration of endovascular therapy, the deep cerebral venous system is not easily accessible with catheters due to small lumens and risk of perforation. It has been proposed that deep cerebral veins may have a higher chance of recanalization if venous thrombus burden is reduced in other parts of the dural venous sinuses. Current literature has not fully explored th...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Morel, B., Hoffman, J., Folzenlogen, Z., Roark, C., Seinfeld, J., Case, D. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

Hemodynamic outcomes of stenting for vertebrobasilar insufficiency in patients with a low flow state
CONCLUSIONS: Our series demonstrates angioplasty and stenting significantly improve intracranial flow over long-term. Angioplasty and stenting may improve the natural history of low-flow VB atherosclerotic disease.PMID:37386804 | DOI:10.1177/15910199231185801
Source: Interventional Neuroradiology - June 30, 2023 Category: Radiology Authors: Timothy G White Richard Bram Justin Turpin Kevin A Shah Prateeka Koul Thomas Link Ali Alaraj Athos Patsalides Sepideh Amin-Hanjani Henry H Woo Source Type: research

Traumatic posterior cerebral artery dissection and dissecting aneurysms: A systematic review with an illustrative case report
CONCLUSIONS: tPCA dissection is diagnosed late and commonly affects the young population. The clinical outcome for this condition is typically favorable. Current endovascular techniques showed considerable efficacy and safety.PMID:36883231 | DOI:10.1177/15910199231162487
Source: Interventional Neuroradiology - March 8, 2023 Category: Radiology Authors: Muhammed Amir Essibayi Panagiotis Kerezoudis Zafer Keser Giuseppe Lanzino Source Type: research

Single-Center Description of Therapeutic Anticoagulation Practices and Outcomes in Large Hemispheric Infarctions
Discussion Although radiographic HT is common among patients with LHI, it does not always portend symptomatic clinical deterioration. Further research regarding AC timing and safety is necessary.
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Breit, H., Sterenstein, A., Abburi, N., Song, S., John, S., Da Silva, I., Koffman, L. Tags: Research Article Source Type: research

E-096 COVID status is related to clot burden during thrombectomy in acute stroke patients
ConclusionOf 230 patients included in this interim analysis across 24 centers in the United States, between 02/2021 and 01/2022, 16 patients had a history of COVID. Comparing COVID-positive to non-positive, patients with COVID were younger (median 66.5 years vs 71.5 years, p 0.042), and had more intracranial clot by weight (median 101.0 mg vs 42.0 mg, p 0.047). There was a trend toward COVID positive patients to have more clot volume (median 180 cc vs 77.5 cc p 0.08), suggesting the difference was a higher clot burden instead of more density to the thrombus. These results suggest different histopathological characteristics...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Dabney, A., Vicari, J., Rivet, D., Woodward, B., Nanda, A., Fiorella, D., Baltan, S., Sohrabji, F., Pennypacker, K., Kellner, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

O-020 The tigertriever 13 distals study: distal ischemic stroke treatment with adjustable low-profile stentriever
ConclusionThe TIGERTRIEVER 13 device with operator controllability and high fluoroscopy visibility and its small size can potentially provide a safe and effective clot removal in patients with distal vessels occlusion.Disclosures D. Fiorella: 1; C; Rapid Medical. R. Gupta: None. R. Chapot: None. J. Saver: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fiorella, D., Gupta, R., Chapot, R., Saver, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-052 The pennsylvania post-market multicenter experience with flow re-direction endoluminal device (FRED)
ConclusionThe results of the early post-market experience with the FRED device show reasonable safety and adequate aneurysmal occlusion rates comparable to other flow diverters. However, more extensive multicenter studies with more extended follow-up data are needed to assess the long-term safety and durability of the device.Abstract O-052 Table 1Baseline descriptive statistics Number of patients n=61 Gender Male 11 (18%) Female 50 (82%) Age (Years: median; IQR) 58 (51 – 68) Multiple Intracranial Aneurysms 21 (34.4%) Family history of aneurysms 9 (14.8%) Smoking History Never smokers 26 (42.6%) Past smokers 13 (21.3...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Salem, M., Kvint, S., Hendrix, P., Al Saiegh, F., Gajjar, A., Goren, O., Gross, B., Jabbour, P., Lang, M., Schirmer, C., Tjoumakaris, S., Griessenauer, C., Burkhardt, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-019 Comparative effectiveness of stent-assisted coiling and woven endobridge (WEB) embolization for the treatment of unruptured wide-neck bifurcation intracranial aneurysms
ConclusionMid-term complete and adequate occlusion rates were similar between patients treated with WEB and SAC. Given the comparable outcomes, there may be equipoise in treatment options for WNBAs.Abstract P-019 Table 1Baseline patient and aneurysm morphology parameters between treatment groups Aneurysm parameters* WEB (n=27) Stent-coil (n=54) p-value Age 63 (50–69) 65 (57–69) 0.511 Gender, male 6 (22%) 12 (22%) 1.000 Smoking Status Current smoker 9 (33%) 9 (17%) 0.235 Prior Smoker 9 (33%) 22 (41%) Never Smoker 9 (33%) 23 (43%) Location Acomm 9 (33%) 20 (37%) 0.772 Basilar apex 6 (22%) 17 (32%) Carotid termin...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kashkoush, A., Desai, A., Davison, M., Achey, R., Mahapatra, A., Patterson, T., Moore, N., Bain, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

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