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Specialty: Cardiovascular & Thoracic Surgery
Condition: Thrombosis

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Total 372 results found since Jan 2013.

Mitral valve repair and bioprosthetic replacement without postoperative anticoagulation does not increase the risk of stroke or mortality ADULT CARDIAC
CONCLUSIONS Despite current guidelines recommending postoperative anticoagulation following MVRR or bioprosthetic replacement, the avoidance of warfarin does not increase perioperative complications and has no impact on intermediate survival. Accordingly, a prospective randomized study to adjudicate the role of extended warfarin thromboprophylaxis in mitral valve surgery is warranted.
Source: European Journal of Cardio-Thoracic Surgery - June 13, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Schwann, T. A., Engoren, M., Bonnell, M., Clancy, C., Khouri, S., Kabour, A., Jamil, T., Habib, R. H. Tags: ADULT CARDIAC Source Type: research

Initial Experience With Minimally Invasive Surgical Exclusion of the Left Atrial Appendage With an Epicardial Clip
Conclusions: Isolated epicardial left atrial clipping is a safe treatment option in high-risk patients with AF. Long-term success in preventing stroke is still to be determined, but short-term results are very encouraging.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - January 1, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Clinical Significance of Spontaneous Echo Contrast on Extracorporeal Membrane Oxygenation
Conclusions SEC on VA-ECMO resulted in an increased risk of intracardiac thrombus and stroke. Maintaining pulsatility while the patient is on ECMO may result in a decreased chance of developing SEC and stroke.
Source: The Annals of Thoracic Surgery - February 16, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Valve-Sparing Root Replacement vs Composite Valve Grafting in Aortic Root Dilation: A Meta-Analysis
ConclusionsAortic valve sparing appears to be safe, and associated with reduced late mortality, thromboembolism/stroke and bleeding compared with composite valve grafting. Late durability is equivalent. Aortic valve sparing should be considered in patients with favorable aortic valve morphology.Graphical abstract
Source: The Annals of Thoracic Surgery - January 23, 2020 Category: Cardiovascular & Thoracic Surgery Source Type: research

Valve-Sparing Root Replacement vs Composite Valve Grafting in Aortic Root Dilation: A Meta-Analysis.
CONCLUSIONS: Aortic valve sparing appears to be safe, and associated with reduced late mortality, thromboembolism/stroke and bleeding compared with composite valve grafting. Late durability is equivalent. Aortic valve sparing should be considered in patients with favorable aortic valve morphology. PMID: 31981499 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - January 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Elbatarny M, Tam DY, Edelman JJ, Rocha RV, Chu MWA, Peterson MD, El-Hamamsy I, Appoo JJ, Friedrich JO, Boodhwani M, Yanagawa B, Ouzounian M, Canadian Thoracic Aortic Collaborative (CTAC) Investigators Tags: Ann Thorac Surg Source Type: research

Minimally invasive, simplified double ‐layer left atrial appendage closure
AbstractThe left atrial appendage (LAA) has been identified as a site of thrombus formation in the heart and as a source of embolism in patients with atrial fibrillation, leading to stroke. Studies suggest that LAA closure may reduce the risk for stroke and the need for anticoagulation; conversely, incomplete closure can increase the stroke risk almost 12 ‐fold. Because open heart surgery is associated with increased risk for subsequent stroke, surgeons generally prefer to close the LAA during heart surgery, as recommended in current atrial fibrillation management guidelines. Building on trends toward minimally invasive ...
Source: Journal of Cardiac Surgery - May 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed Alnajar, Corinne Aberle, Joseph Lamelas Tags: SURGICAL TECHNIQUE Source Type: research

Antithrombotic strategy variability in atrial fibrillation and obstructive coronary disease revascularised with percutaneous coronary intervention: primary results from the AVIATOR 2 international registry
CONCLUSIONS: The AVIATOR 2 study is the first digital health study examining physician-patient perspectives on ATT choices after AF-PCI. TT was the most common strategy without differences in 1-year outcomes in ATT strategy. Physicians rated safety first when prescribing ATT; patients feared stroke over bleeding.CLINICALTRIALS: gov: NCT02362659.PMID:35656720 | DOI:10.4244/EIJ-D-21-01044
Source: EuroIntervention - June 3, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Jaya Chandrasekhar Usman Baber Samantha Sartori Ridhima Goel Johny Nicolas Birgit Vogel Clayton Snyder Annapoorna Kini Carlo Briguori Bernhard Witzenbichler Ioannis Iakovou Gennaro Sardella Kevin Marzo Anthony DeFranco Thomas Stuckey Alaide Chieffo Antoni Source Type: research

064 * ten-year results of redo aortic valve surgery in current practice: results from the multicentre european redo cardiac operations research database (record) initiative
Conclusions: rAVR still achieve satisfactory results. Baseline risk-factors and perioperative complications affecting outcome can be targets for TAVR and for improvements in perioperative management respectively.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Onorati, F., Biancari, F., De Feo, M., Mariscalco, G., Messina, A., Santarpino, G., Santini, F., Faggian, G. Tags: Aortic valve replacement: Long-term outcomes Source Type: research

Early Anticoagulation drug regimens after WATCHMAN Left Atrial Appendage Closure: safety and efficacy.
CONCLUSIONS: LAA closure with the Watchman device is feasible in patients with relative or absolute contraindication to oral anticoagulation. Neither DAPT nor NOAC therapy lead to a significant increase in device thrombus, stroke or bleeding compared to the standard VKA regimen. NOAC therapy had the numerically lowest event rate. PMID: 28606886 [PubMed - as supplied by publisher]
Source: EuroIntervention - June 16, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Left atrial appendage occlusion with the AMPLATZER ™ Amulet™ device: one-year follow-up from the prospective global Amulet Registry.
CONCLUSIONS: In the global prospective Amulet Registry of patients at high-risk of stroke and bleeding, the annualised ischaemic stroke rate was 2.9%. The LAA was sealed in 98.4% after 1-3 months and device related thrombus was observed in 1.7% of cases with only a minority of all patients on anticoagulation treatment. PMID: 29806820 [PubMed - as supplied by publisher]
Source: EuroIntervention - May 31, 2018 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research