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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Thrombosis
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Total 415 results found since Jan 2013.
Nerve function differs according to selection of treatment for symptomatic cerebral aneurysms
【Background】The Pipeline Flex Embolization Device (PED) has paved the way for a new stage of treatment selection. Flow diverters change the flow to thrombosed aneurysms and thus do not deteriorate the mass effect. However, thrombosis is associated with the induction of inflammation that could be come a concern if it spreads to surrounding nerves.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Hideo Chihara, Akira Ishii, Nobutake Sadamasa, Yasutoshi Kai, Makoto Saka, Mitsusige Ando, Wataru Takita, Keisuke Tokunaga, Taketo Hatano, Izumi Nagata Source Type: research
Clinical outome of weekend and nighttime admitted patients due to acute ischemic stroke
【Background and Purpose】Acute ischemic stroke (AIS) requires urgent diagnosis and subsequent treatment including thrombolytic or neuroendovascular revascularization (tNER). AIS is time-sensitive and weekend and nighttime admission (ENtime) may be associated with poor clinical outcome because of therapeutic delay. The aim of our study was to investigate diferrences in any in-hospital mortality and clinical outcome between ENtime and weekday daytime (DDtime) admitted patients due to AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Noriyoshi Nakai, Takahisa Mori, Yuichi Tanno, Shigen Kasakura, Kazuhiro Yoshioka Source Type: research
Developments in Stent retriever position and recanalization rate
【Introduction】Mechanical thrombectomy in acute cerebral large vessels occlusive disease, its usefulness has been demonstrated in 2015 ISC. As device, in MR CLEAN, stent retriever device (: SRD) it has been used in 97%. The positional relationship between the SRD and the thrombus can be confirmed in the image, but report that examined the difference in the recanalization rate (pass number of times and TICI) due to the positional relationship.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Masataka Takeuchi, Michitsura Yoshiyama, Tadateru Goto Source Type: research
Combined mechanical thrombectomy technique using retrieval stent (Trevo) and intermediate access guiding catheter (5 DAC)
【Introduction】Recently, mechanical thrombectomy with retrieval stent was the most preferred method of the available options in the management of acute ischemic stroke due to large vessel occlusions. When we retrieve the stent, the embolization to uninvolved vessel by the fragmentation of entrapp ed thrombus, “missing clot”, is one of the important complications. We tried to do mechanical thrombectomy with retrieval stent and 5 DAC simultaneously for it.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Kuhyun Yang, Seung-Hoon You, Woo-Young Jang, Moon-Kyu Lee, Kwang-Deog Jo Source Type: research
Study of a novel small molecule, LT3001, in a thromboembolic stroke model in non-human primates
LT3001 is a novel small molecule designed to have thrombolytic and free radical scavenging activities. Its potential safety and efficacy in treating acute ischemic stroke was evaluated using a thromboembolic stroke model in adult Cynomolgus macaque.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Sheng-Wen Yeh, Tzulin Yeh, Wendy Huang Source Type: research
Proteomic analysis to determine stroke thrombus origin
In this study, we used mass spectrometry to evaluate the protein composition of retrieved emboli from three patients with differing stroke etiologies.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Neal Matsumori Rao, Joseph Capri, Whitaker Cohn, William H. Yong, Lucas Restrepo-Jimenez, David S. Liebeskind, Julian P. Whitelegge Source Type: research
Utility of items of baseline NIH stroke scale as predictors of functional outcomes 3 months after mild ischemic stroke
We examined the utility of individual NIH Stroke Scale (NIHSS) score items or clusters of items as predictors of f unctional outcomes 3 months after mild stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Jay Chol Choi, Jun Lee, Jae-Kwan Cha, Joon-Tae Kim, Hee-Joon Bae Source Type: research
Spinal cord injury misdiagnosed as cerebral infarction and given thrombolytic therapy: A case report
【Background】Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) covers a broad spectrum of neurological deficits, which can be confused with cerebral infarction when patients present with hemiparesis and a history of minor injury.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Jie Yang, Jing Hang, Junshan Zhou, Yingdong Zhang Source Type: research
Microbubble-Based Sonothrombolysis Using a Planar Rectangular Ultrasonic Transducer
The aim of the proposed study was to evaluate in an in vitro flow model the ability of small planar rectangular (2 × 10 mm2) ultrasonic transducer to enhance thrombolysis induced by the thrombolytic agent tenecteplase (TNK-tPA).
Source: Journal of Stroke and Cerebrovascular Diseases - February 20, 2017 Category: Neurology Authors: Nicos Papadopoulos, Christakis Damianou Source Type: research
Sequential Multiple Assignment Randomized Trials: An Opportunity for Improved Design of Stroke Reperfusion Trials
Modern clinical trials in stroke reperfusion fall into 2 categories: alternative systemic pharmacological regimens to alteplase and “rescue” endovascular approaches using targeted thrombectomy devices and/or medications delivered directly for persistently occluded vessels. Clinical trials in stroke have not evaluated how initial pharmacological thrombolytic management might influence subsequent rescue strategy. A sequential multiple assignment randomized trial (SMART) is a novel trial design that can test these dynamic treatment regimens and lead to treatment guidelines that more closely mimic practice.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2017 Category: Neurology Authors: William J. Meurer, Nicholas J. Seewald, Kelley Kidwell Source Type: research
Prosthetic Valve Thrombosis in the Acute Phase of the Stroke: Relevance of Detection and Follow-Up
Stroke may be the first symptom of prosthetic valve thrombosis (PVT); therefore, rapid diagnosis and therapy are crucial. We aimed to evaluate the prevalence, main predictors, and long-term clinical evolution of patients with PVT in the acute phase of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2017 Category: Neurology Authors: Jacint Sala-Padro, Jorge Pagola, Maria Teresa Gonzalez-Alujas, Laia Sero, Jesus Juega, Noelia Rodriguez-Villatoro, Sandra Boned, David Rodriguez-Luna, Marian Muchada, Ruben Fernandez-Galera, Marta Rubiera, Marc Ribo, Arturo Evangelista, Carlos Molina Source Type: research
Cerebral Venous Sinus Thrombosis Presenting Feature of Systemic Lupus Erythematosus
CVST (cerebral venous sinus thrombosis) may sometimes be associated with autoimmune disorders that require specific treatment. The clinical and magnetic resonance imaging (MRI) findings of systemic lupus erythematosus (SLE) patients with CVST are presented and contrasted with CVST without SLE.
Source: Journal of Stroke and Cerebrovascular Diseases - January 4, 2017 Category: Neurology Authors: Rajesh Kumar Singh, Sanjeev Kumar Bhoi, Jayantee Kalita, Usha Kant Misra Source Type: research
Multiple Thromboembolic Cerebral Infarctions from the Aorta in a Patient with Churg –Strauss Syndrome
We report a case of cerebral infarction in a patient with CSS due to embolism from a thrombus on the wall of the aorta.
Source: Journal of Stroke and Cerebrovascular Diseases - December 15, 2016 Category: Neurology Authors: Hideo Okada Tags: Case Studies Source Type: research
Venous Infarcts Mimicking Large Vessel Arterial Disease: Watershed Lesions in Deep Cerebral Venous Thrombosis
We read with interest the recent report by Washida et al on multiple deep white matter hyperintensities seen in diffusion-weighted imaging (DWI) in a patient with straight sinus thrombosis.1 We would like to report a similar instance of a 30-year-old female who presented to us with a 4-day history of headache, vomiting, and progressive drowsiness; on examination, she was drowsy and had left hemiparesis. Her initial magnetic resonance imaging demonstrated thalamic and basal ganglia signal changes and bilateral centrum semiovale punctate infarcts (Fig 1, A,B) that suggested possible deep cerebral venous sinus thrombosis a...
Source: Journal of Stroke and Cerebrovascular Diseases - December 7, 2016 Category: Neurology Authors: Ravinder-Jeet Singh, Jitender Saini, Vikram V. Holla, Nitish Kamble Tags: Letter to the Editor Source Type: research
Fusiform Left Carotid-Ophthalmic Artery Aneurysm Presenting with Central Retinal Artery Occlusion
We describe the case of acute non-arteritic CRAO associated fusiform internal carotid-ophthalmic artery aneurysm with intraluminal thrombus. Despite the rarity of this condition, we suggest that carotid-ophthalmic artery aneurysm should be included in the differential diagnosis of CRAO.
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2016 Category: Neurology Authors: Rima M. Dafer, John H. Pula, Shakeel Chowdhry Tags: Case Studies Source Type: research
