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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Thrombosis

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Total 415 results found since Jan 2013.

Campaign —Once Again Streptokinase Trials (COAST) in Acute Ischemic Stroke
Every year, 1.5 million people suffer from stroke worldwide, the leading cause of disability and the second most common cause of death.1 Stroke incidence in developing countries is much higher and is further rising,2 whereas access to effective acute stroke treatment is very limited. Only 1% stroke sufferers in developing countries have access to the highly expensive tissue plasminogen activator (tPA), the only proven and recommended thrombolytic agent for acute ischemic stroke treatment.3
Source: Journal of Stroke and Cerebrovascular Diseases - December 18, 2017 Category: Neurology Authors: Muhammad Shabbir, Arsalan Ahmad Tags: Letter to the Editor Source Type: research

Incidental Thrombotic Thrombocytopenic Purpura during Acute Ischemic Stroke and Thrombolytic Treatment
In this study, a patient with AIS and thrombotic thrombocytopenic purpura (TTP) symptoms during thrombolytic treatment was presented.
Source: Journal of Stroke and Cerebrovascular Diseases - November 28, 2017 Category: Neurology Authors: İbrahim Acır, Hacı Ali Erdoğan, Vildan Yayla, Nilay Taşdemir, Murat Çabalar Tags: Case Report Source Type: research

Thrombolytic Therapy of Acute Ischemic Stroke during Early Pregnancy
Thrombolytic treatment (recombinant tissue plasminogen activator [rt-PA]) has established efficacy in acute ischemic stroke, but pregnancy has been an exclusion criterion for all clinical trials that validated alteplase in acute stroke, so our knowledge about its use in this condition is limited.Herein we report the successful use of intravenous rt-PA thrombolysis, uncomplicated by neither hemorrhage development nor other complication in a woman who was 13 weeks pregnant with acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 28, 2017 Category: Neurology Authors: Anne Landais, Hugo Chaumont, Rachel Dellis Tags: Case Studies Source Type: research

Incidental Thrombotic Thrombocytopenic Purpura during Acute Ischemic Stroke and Thrombolytic Treatment
In this study, a patient with AIS and thrombotic thrombocytopenic purpura (TTP) symptoms during thrombolytic treatment was presented.
Source: Journal of Stroke and Cerebrovascular Diseases - November 28, 2017 Category: Neurology Authors: İbrahim Acır, Hacı Ali Erdoğan, Vildan Yayla, Nilay Taşdemir, Murat Çabalar Tags: Case Report Source Type: research

Thrombectomy Using “Clamping Embolus with Semi-Retrieval” Technique in Acute Ischemic Stroke
This study aims to describe technical results of the thrombectomy with clamping embolus technique (TCET) method in acute ischemic stroke. This study also aims to evaluate the efficiency of mechanical thrombectomy by TCET, and to compare it with conventional stent retriever thrombectomy (CSRT).
Source: Journal of Stroke and Cerebrovascular Diseases - November 16, 2017 Category: Neurology Authors: Zhen-Sheng Liu, Long-Jiang Zhou, Yong Sun, Xiong-Wei Kuang, Jia-Xiang Wang, Xin-Jiang Zhang Source Type: research

Safe Readministration of Intravenous Thrombolysis in Recurrent Basilar Thrombosis
This report adds to the very limited literature on the topic demonstrating safe and successful use of repeat IV thrombolysis following a previous recent stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 31, 2017 Category: Neurology Authors: Alina Khan, Ahmed Itrat Tags: Case Studies Source Type: research

Association between Transverse Sinus Hypoplasia and Cerebral Venous Thrombosis: A Case-Control Study
Hypoplasia of the transverse sinus (TS) is a common anatomical variation. However, the relationship between TS hypoplasia and venous thrombosis has not been studied. We analyzed the hypothesis that TS hypoplasia is a predisposing factor for ipsilateral thrombosis.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2017 Category: Neurology Authors: Antonio Arauz, Monica Chavarria-Medina, Hern án M. Patiño-Rodriguez, Elizabeth Varela, Fabiola Serrano, Mayra Becerril, Miguel A. Barboza Source Type: research

Outcomes of Nonagenarians with Acute Ischemic Stroke Treated with Intravenous Thrombolytics
Nonagenarians are under-represented in thrombolytic trials for acute ischemic stroke (AIS). The effectiveness of intravenous thrombolytics in nonagenarians in terms of safety and outcome is not well established.
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2017 Category: Neurology Authors: R éza Behrouz, Jaime Masjuán-Vallejo, Rocío Vera, Joshua Z. Willey, Mickael Zedet, Solène Moulin, Charlotte Cordonnier, Catharina J.M. Klijn, Karin Kanselaar, Maaike Dirks, Brian Silver, Muhib Khan, Mahmoud R. Azarpazhooh, Daniel A. Godoy, Christine R Source Type: research

Isolated Internal Carotid Artery Thrombus and Cerebral Infarction in a Patient with Necrotizing Pancreatitis: Case Report
We report a case of a patient presenting with right arm weakness, slurred speech, and altered mental status in the setting of acute on chronic pancreatitis. The patient was found to have scattered left cerebral hemisphere cortical infarctions, and catheter angiography confirmed the presence of intraluminal left ICA thrombus, with no evidence of atherosclerotic disease in the cervical or intracranial vasculature.
Source: Journal of Stroke and Cerebrovascular Diseases - September 8, 2017 Category: Neurology Authors: Daniel R. Ludwig, Matthew J. Austin, Adam N. Wallace, Mudassar Kamran, Akash P. Kansagra, Joshua W. Osbun, DeWitte T. Cross, Christopher J. Moran Tags: Case Studies Source Type: research

Drip-and-Ship Thrombolytic Therapy for Acute Ischemic Stroke
Neuroendovascular therapy is a common treatment for patients with acute ischemic stroke of the anterior circulation who fail to respond to recombinant tissue plasminogen activator. However, although most hospitals can provide recombinant tissue plasminogen activator therapy, many cannot perform neuroendovascular therapy. Thus, use of a drip-and-ship treatment-liaison system allowing recombinant tissue plasminogen activator-treated patients to be transferred to facilities offering neuroendovascular therapy is important.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2017 Category: Neurology Authors: Ichiro Deguchi, Satoko Mizuno, Shinya Kohyama, Norio Tanahashi, Masaki Takao Source Type: research

Treatment of Cryptogenic Stroke with Active Cancer with a New Oral Anticoagulant
Low-molecular weight heparin (LMWH) was shown to be effective and safe in treating venous thromboembolism, and generally used for stroke in cancer patients, but its effects on stroke are unclear. We compared clinical outcomes between LMWH and new oral anticoagulant (NOAC) in patients with cancer-related stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 23, 2017 Category: Neurology Authors: Ki-Woong Nam, Chi Kyung Kim, Tae Jung Kim, Sang Joon An, Kyungmi Oh, Sang-Bae Ko, Byung-Woo Yoon Source Type: research

Huge Free-Floating Thrombus in the Internal Carotid Artery
A 70-year-old male patient presented with very short recurrent speech difficulty and left-sided monocular transient visual loss. The patient was diagnosed with Crohn's disease and had hemicolectomy due to obstruction 10 years ago. He also had a history of coronary artery disease, hypertension, left femoral vein thrombosis, and 50-pack-year smoking. He had no stroke attack before. He was taking regularly dual antiplatelet therapy and azathioprine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Uygur Tanriverdi, Osman Kizilkilic, Birsen Ince Tags: Letter to the Editor Source Type: research

Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF- κB–Mediated Inflammatory and Apoptotic Responses
Isosteviol sodium (STVNa) has been reported to have neuroprotective effects against ischemia/reperfusion (I/R) injury in rats. Furthermore, recanalization treatments, including thrombolytic therapy, have several limitations. Excessive inflammation and apoptosis contribute to the pathogenesis of ischemic brain damage. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF- κB) is critical to these processes and is associated with cerebral ischemia. Therefore, we studied the potential therapeutic effects and mechanisms of STVNa on permanent cerebral ischemia in mice.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2017 Category: Neurology Authors: Hao Zhang, Xiaoou Sun, Yanxiang Xie, Jie Zan, Wen Tan Source Type: research

Multiple Lacunar Infarcts in Paroxysmal Nocturnal Hemoglobinuria
We report a case of a 49-year-old woman who has a medical history of diabetes mellitus, hypertension, and PNH and presented multiple lacunar strokes in a routine consultation with a hematologist.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2017 Category: Neurology Authors: Alex Tiburtino Meira, Gabriel Sampaio Froehner, Andr é Petean Trindade, Silméia Garcia Zanati Bazan, Gabriel Pereira Braga, Rodrigo Bazan Tags: Case Studies Source Type: research

Left Upper Lung Lobectomy Is an Embolic Risk Factor for Cerebral Infarction
Cerebral embolism is typically caused by a cardiogenic thrombus. The patent foramen ovale is a well-known cause of paradoxical embolism. However, some idiopathic cases of stroke have been reported. Such strokes are designated as embolic stroke of undetermined sources. Among them, lung lobectomy may be a new embolic risk factor for cerebral embolism. The risk of thrombus formation is high at the pulmonary vein stump after lung lobectomy, especially in the left upper lobe. Interestingly, the risk remains several years after surgery.
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2017 Category: Neurology Authors: Yuya Kobayashi, Hiroyuki Yahikozawa, Ryota Takamatsu, Rie Watanabe, Kenichi Hoshi, Wataru Ishii, Shunichi Sato Tags: Case Studies Source Type: research