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Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Effect of mitral regurgitation on stroke risk in patients with non-rheumatic atrial fibrillation
CONCLUSION: In our large registry of patients with non-rheumatic AF, we did not find a protective effect of grade 3-4 MR on the risk of stroke.PMID:36030169 | DOI:10.1016/j.acvd.2022.05.006
Source: Archives of Cardiovascular Diseases - August 27, 2022 Category: Cardiology Authors: Sergio Raposeiras-Roub ín Pablo Dom ínguez-Erquicia Emad Abu-Assi Ana Ledo-Pi ñeiro Andr é González-García Carla Iglesias-Otero Enrique Garc ía-Campo Andr és Íñiguez-Romo Source Type: research

Managing uncertainty: Physicians' decision-making for stroke prevention for patients with atrial fibrillation and intracerebral haemorrhage
Conclusion Physicians described the process of deciding on stroke prevention in patients with AF post-ICH as 'challenging' due to considerable 'clinical equipoise'. Key factors that affected decision-making was patient comorbidities, functional status, and patient willingness to engage with oral anticoagulation therapy. Shared decision-making was believed to be beneficial, but physicians believed that the ultimate responsibility to decide on stroke prevention lay with the clinician.PMID:35253141 | DOI:10.1055/a-1789-4824
Source: Thrombosis and Haemostasis - March 7, 2022 Category: Hematology Authors: Elena Ivany Robyn Lotto Gregory Yh Lip Deirdre Lane Source Type: research

Outcomes measured by mortality rates, quality of life and degree of autonomy in the first year in stroke units in Spain
Conclusions: There has been a change in the prognosis for stroke in Spain in recent years as the quality of life at 1 year observed in our study is clearly higher than that obtained in other Spanish studies conducted previously. Moreover, survival and functional outcome have also improved following the introduction of a new model of care. These results clearly promote extension of the model based on stroke units and reinforced rehabilitation to the majority of the more than 100,000 strokes that occur annually in Spain.
Source: Health and Quality of Life Outcomes - March 17, 2015 Category: Global & Universal Authors: Javier MarJaime MasjuanJuan Oliva-MorenoNuria Gonzalez-RojasVirginia BecerraMiguel CasadoCovadonga TorresMaría YebenesManuel QuintanaJose Alvarez-Sabínon behalf of CONOCES Investigators Group Source Type: research

Modeling the potential efficiency of a blood biomarker-based tool to guide pre-hospital thrombolytic therapy in stroke patients
ConclusionsThe use of a blood biomarker test to guide pre-hospital thrombolysis is cost-effective compared with standard hospital care in patients with ischemic stroke.
Source: The European Journal of Health Economics - July 27, 2022 Category: Health Management Source Type: research

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