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Condition: Stroke
Management: National Institutes of Health (NIH)

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Total 1650 results found since Jan 2013.

Efficacy and safety of a sequential treatment with clearing heat and eliminating phlegm and tonifying and activating blood circulation in treating acute ischemic stroke: study protocol for a randomized controlled trial
DISCUSSION: The results of this study will provide objective and scientific data with which to assess the efficacy and safety of a sequential treatment based on "integrating disease and symptom pattern" for patients with AIS.PMID:35848977 | DOI:10.19852/j.cnki.jtcm.20220617.003
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Zhou Ziyi Wan Can Zhao Yuanqi Liu Xiangzhe Gao Ying A N Hongwei L I Lejun Zhang Huili Y U Xiaofei Zhang Xinchun Wang Huijuan Shi Qing Wei Chunhua Chen Jie Huang Wenguo Chen Junbin Gao Ying H U Mingzhe Cai Yefeng Source Type: research

TEARS: a longitudinal investigation of the prevalence, psychological associations and trajectory of poststroke emotionalism
This study aimed to assess the prevalence and course of PSE over the first year poststroke, and its psychological associations. Methods Consenting stroke survivors who were physically and cognitively able to participate were assessed within 2 weeks, 6 and 12 months of stroke to determine PSE point prevalence using a diagnostic, semistructured PSE interview (Testing Emotionalism After Recent Stroke-Diagnostic Interview). At the same assessments, neuropsychological and disability status were determined using Hospital Anxiety and Depression Scale, Abbreviated Mental Test, National Institute of Health Stroke Scale, Barthel In...
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2022 Category: Neurosurgery Authors: Broomfield, N. M., West, R., Barber, M., Quinn, T. J., Gillespie, D., Walters, M., House, A. Tags: Editor's choice Neuropsychiatry Source Type: research

Association of cognitive reserve with stroke outcome: a protocol for a systematic review
Introduction The concept of cognitive reserve (CR) was introduced to account for individual differences in the clinical manifestation of neurodegenerative diseases. Though several mechanisms and risk factors are shared between neurodegeneration and stroke, the effect of CR on poststroke functional outcome has been poorly addressed. This systematic review aims to synthesise the available research evidence on the association of CR with stroke outcome, in order to implement the understanding of interindividual variability in stroke outcome and to improve its prediction. Methods and analysis Cochrane Library, Embase, PubMed, ...
Source: BMJ Open - July 8, 2022 Category: General Medicine Authors: Gallucci, L., Umarova, R. M. Tags: Open access, Neurology Source Type: research

Stroke severity modified the effect of chronic atrial fibrillation on the outcome of thrombolytic therapy
This study was designed to identify high-risk patients with chronic AF who had undergone thrombolysis treatment and to explore whether the baseline National Institutes of Health Stroke Scale (NIHSS) could be used to distinguish poor clinical outcomes in thrombolyzed patients.
Source: Medicine - July 1, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Association of Changed Serum Brain Biomarkers With Perihematomal Edema and Early Clinical Outcome in Primary ICH Patients
Background: Perihematomal edema (PHE) following primary intracranial hemorrhages (ICHs) affects the patient outcome. Also, serum biomarkers such as S100 calcium-binding protein B (S100B) and glial fibrillary acidic protein (GFAP) have been associated with ICHs outcome. We aimed to investigate the association between these biomarkers and PHE in ICH patients. Methods: In this cross-sectional study, patients with primary ICH between January 2020 and August 2020 were evaluated. All participants underwent spiral brain computed tomography scans upon admission, and 48 to 72 hours later and quantification of initial hem...
Source: The Neurologist - July 1, 2022 Category: Neurology Tags: Original Articles Source Type: research

Large Middle Cerebral Artery Ischemic Stroke in a Therapeutically Anticoagulated Patient With Severe SARS-CoV-2 Infection
Introduction: Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with hypercoagulability which can predispose infected patients to both arterial and venous thromboembolic complications. Despite therapeutic anticoagulation, there remains a risk of ischemic strokes, which may lead to adverse patient outcomes. Only a few cases are described in the literature regarding SARS-CoV-2 positive patients developing thrombotic ischemic strokes despite therapeutic anticoagulation. Case Report: The following is a case discussion regarding a 71-year-old female with pas...
Source: The Neurologist - July 1, 2022 Category: Neurology Tags: Case Report/Case Series Source Type: research