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Interactive association between insomnia symptoms and sleep duration for the risk of dementia —a prospective study in the Swedish National March Cohort
ConclusionInsomnia and short sleep duration increase the risk of dementia amongst middle-aged to older adults.
Source: Age and Ageing - September 7, 2023 Category: Geriatrics Source Type: research

COVID-19 and brain aging: what are the implications of immunosenescence?
Curr Aging Sci. 2022 Dec 28. doi: 10.2174/1874609816666221228103320. Online ahead of print.ABSTRACTThe human lifespan is increasing, and mankind is aging. It is estimated that, until the year 2050, this population worldwide will reach 22% of the total world population. Along with aging, the human immunologic system changes, a process called immunosenescence or even inflammaging. The aging immune system increases mortality and morbidity in the elderly mainly because it loses its capacity to react against internal and external aggressions. There is a decrease in B and T lymphocytes and CD4+ lymphocytes lose the CD28 protein ...
Source: Current Aging Science - December 29, 2022 Category: Geriatrics Authors: Gabriela Serafim Keller Eduarda Behenck Medeiros Maria Laura Cecconi Dos Santos Adrielly Vargas Lidio Ewa Kucharska Josiane Budni Source Type: research

Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their pathogenesis and clinical manifestations in the case of COVID-19. The risk factors, mechanisms of development, diagnostic approach, and the age characteristics of patients with neurological complications of COVID-19 are discussed. The specific mechanisms of the neuroinvasiveness and neurovirulence of the SARS-CoV-2 virus, regardless of the age of patients and the presence of risk factors, lead to systemic damage to the endothelium of small-caliber vessels, generalized thrombov...
Source: Advances in Gerontology - December 1, 2022 Category: Geriatrics Source Type: research

A Systematic Review of the Impact of Select Mindfulness Interventions on Psychological Outcomes among Older Adults with Chronic Health Conditions
CONCLUSIONS: Early evidence for MIs impact on psychological outcomes is promising, though more work involving randomized control trials is needed. Current studies generally lack methodological rigor and have a high risk of bias. Given the high rates of chronic pain in older adults and the emerging evidence for MIs, future work in this area is of particular value.CLINICAL IMPLICATIONS: Practitioners should be guardedly optimistic about the value of MIs and ACT for older adults with chronic health conditions.PMID:35585039 | DOI:10.1080/07317115.2022.2076636
Source: Clinical Gerontologist - May 18, 2022 Category: Geriatrics Authors: Jay Kayser Rita Xiaochen Hu Danielle Rosenscruggs Lydia Li Xiaoling Xiang Source Type: research

More than a quarter century of the most prescribed sleeping pill: Systematic review of zolpidem use by older adults.
Abstract Zolpidem is widely used to treat insomnia of older adults despite that few randomized controlled studies were conducted in this group. We systematically reviewed the relevant literature on efficacy/effectiveness and safety of zolpidem use by elderly individuals in relevant databases completed with a manual search of key journals. Studies were required to include individuals aged ≥60 years under intervention with zolpidem compared to placebo or other hypnosedatives. Outcomes were either objectively- or subjectively-assessed improvements in specific sleep parameters and safety for clinical use. The 31 r...
Source: Experimental Gerontology - April 29, 2020 Category: Geriatrics Authors: Machado FV, Louzada LL, Cross NE, Camargos EF, Dang-Vu TT, Nóbrega OT Tags: Exp Gerontol Source Type: research

A stroke of bad luck: new-onset mania in elderly patient following undetected stroke, a case report
The phenomenon of developing depression after a stroke is fairly common in the literature (29%) but developing mania after a stroke is rare reportedly to be 1-2% of stroke survivors (Starkstein). One of the earliest descriptions of mania after stroke was described in 1989 of the right hemisphere (Starkstein). In 2011, a systematic review looking at 32 studies identified 49 cases describing symptoms of mania post-stroke. At initial presentation, 92% of these patients presented with elevated mood, 71% with increased rate of speech, 69% with insomnia and 63% with agitation (Santos).
Source: The American Journal of Geriatric Psychiatry - March 14, 2020 Category: Geriatrics Authors: Carolina Osorio, Stephanie Bolton, Hans von Walter, Mamdouh Hanna Tags: Poster Number: NR - 21 Source Type: research

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