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Condition: Hemorrhagic Stroke
Procedure: Perfusion

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Total 533 results found since Jan 2013.

Extended Multimodal Flat Detector CT Imaging in Acute Ischemic Stroke: A Pilot Study
AbstractBy using Flat detector computed tomography (FD-CT), a one-stop-shop approach in the diagnostic workup of acute ischemic stroke (AIS) might be achieved. Although information on upstream vessels is warranted, dedicated FD-CT protocols which include the imaging of the cervical vasculature are still lacking. We aimed to prospectively evaluate the implementation of a new multimodal FD-CT protocol including cervical vessel imaging in AIS patients. In total, 16 patients were included in this study. Eight patients with AIS due to large vessel occlusion (LVO) prospectively received a fully multimodal FD-CT imaging, includin...
Source: Journal of Digital Imaging - January 17, 2023 Category: Radiology Source Type: research

Falsely normal CT perfusion ischemic core readings are common and often associated with deep infarcts
Conclusions CTP may completely fail to detect ischemic core in as many as 25% of cases, especially in isolated deep MCA strokes. Technical refinements of the post-processing algorithms are therefore warranted. TMC infarcts may have a lower risk of reperfusion hemorrhage, potentially due to greater preservation of the neurovascular unit structure in face of delayed recovery of cerebral blood flow.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Bouslama, M., Ravindran, K., Rodrigues, G. M., Pisani, L., Haussen, D. C., Frankel, M. R., Nogueira, R. G. Tags: Neuroimaging Source Type: research

Large mismatch profile predicts rapidly progressing brain edema in acute anterior circulation large vessel occlusion patients undergoing endovascular thrombectomy
ConclusionIn patients with anterior circulation LVO stroke undergoing successful EVT, a large mismatch ratio at baseline is a protective factor for RPBE, which is associated with poor outcomes.
Source: Frontiers in Neurology - January 4, 2023 Category: Neurology Source Type: research

More is less: Effect of ICF-based early progressive mobilization on severe aneurysmal subarachnoid hemorrhage in the NICU
DiscussionWe conclude that the ICF-based early progressive mobilization protocol is an effective and feasible intervention tool. For validity, more mobilization interventions might lead to less pneumonia, duration of mechanical ventilation and length of stay for patients with severe aSAH in the NICU, Moreover, it is necessary to pay attention over potential adverse events (especially line problems), although we did not find serious safety events.
Source: Frontiers in Neurology - December 14, 2022 Category: Neurology Source Type: research

Imaging mismatch between Alberta Stroke Program Early CT Score and perfusion imaging may be a good variable for endovascular treatment
ConclusionsPatients with imaging mismatch treated within 24 h could benefit from EVT and without increasing the risk of sICH.Key Points•Patients with imaging mismatch between ASPECTS and ischemic core could achieve good outcomes after endovascular treatment.•Compared with large ischemic core, patients with imaging mismatch presented lower risk of symptomatic hemorrhage within 6 h and higher proportion of good outcomes within 6 –24 h.•Baseline NIHSS score, ASPECTS, ischemic core, and symptomatic intracranial hemorrhage were associated with good outcomes.
Source: European Radiology - December 11, 2022 Category: Radiology Source Type: research

Estimated pulse-wave velocity predicts survival in patients requiring extracorporeal membrane oxygenation
CONCLUSIONS: ePWV is a promising marker for risk-stratification in ECMO patients. Further investigation is required to better delineate the role of arterial health assessment in disease trajectory and strengthen the validity of AS as a marker of interest in medical and surgical management.PMID:36419384 | DOI:10.1177/02676591221141963
Source: Perfusion - November 24, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Mohsyn I Malik Dave Nagpal Source Type: research

Endovascular treatment beyond 24 hours from the onset of acute ischemic stroke: the Italian Registry of Endovascular Thrombectomy in Acute Stroke (IRETAS)
Conclusions These findings suggest that, in a real world setting, very late endovascular therapy is feasible in appropriately selected patients.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Casetta, I., Fainardi, E., Pracucci, G., Saia, V., Vallone, S., Zini, A., Bergui, M., Cerrato, P., Nappini, S., Nencini, P., Gasparotti, R., Saletti, A., Causin, F., Romano, D., Burdi, N., Giorgianni, A., Mangiafico, S., Toni, D., The Italian Registry of Tags: Ischemic stroke Source Type: research

Rule-based natural language processing for automation of stroke data extraction: a validation study
ConclusionsRule-based NLP has a moderate to good performance for stroke-related data extraction from free-text imaging reports. The algorithm ’s accuracy was affected by inconsistent report styles and lexicon among reporting radiologists.
Source: Neuroradiology - November 9, 2022 Category: Radiology Source Type: research

Radiographic risk factors for intracranial hemorrhage in patients with left ventricular assist devices
Patients with end-stage cardiomyopathy may require the use of mechanical circulatory support to maintain perfusion of the vital organs. This is most commonly achieved using an implantable left ventricular assist device (LVAD), typically used as a bridge to orthotopic heart transplant (BTT) or as destination therapy (DT) for those who are not transplant candidates. An LVAD is usually considered for those patients whose disease and symptoms meet INTERMACS Levels 2-4 criteria, indicating a significant decrease in functionality.
Source: Journal of Stroke and Cerebrovascular Diseases - November 1, 2022 Category: Neurology Authors: Nicholas S. Hernandez, Matthew Kanter, Vaishnavi Sharma, Andy Wang, Michael Kiernan, Delia Kryzanski, Robert Heller, Tara Nail, Ron I. Riesenburger, James T. Kryzanski Source Type: research

Lumbrokinase regulates endoplasmic reticulum stress to improve neurological deficits in ischemic stroke
In this study, we aimed to clarify the neuroprotection of lumbrokinase in mice subjected to permanent middle cerebral artery occlusion. Lumbrokinase significantly attenuated infarct volume and improved neurological dysfunction. Lumbrokinase dramatically decreased the expressions of the endoplasmic reticulum (ER) transmembrane receptor protein inositol-requiring enzyme-1 (IRE1) and its downstream transcription factor, XBP-1, caspase-12, and NF-κB activity, thereby significantly inhibiting apoptosis and autophagy and decreasing the NLRP3 inflammasome. Our evidence indicates that post-stroke treatment with lumbrokinase prote...
Source: Neuropharmacology - October 12, 2022 Category: Drugs & Pharmacology Authors: Yi-Hsin Wang Jiuan-Miaw Liao Ke-Min Chen Hsing-Hui Su Pei-Hsun Liu Yi-Hung Chen Yuang-Seng Tsuei Chin-Feng Tsai Shiang-Suo Huang Source Type: research