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Specialty: Drugs & Pharmacology
Condition: Hemorrhagic Stroke
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Total 692 results found since Jan 2013.
Stroke-prone Spontaneously Hypertensive Rats Have Reduced Hydroxysteroid 17- β Dehydrogenase 7 Levels for Low Cholesterol Biosynthesis.
Stroke-prone Spontaneously Hypertensive Rats Have Reduced Hydroxysteroid 17-β Dehydrogenase 7 Levels for Low Cholesterol Biosynthesis.
Clin Exp Pharmacol Physiol. 2019 Oct 06;:
Authors: Matsuoka H, Uchino Y, Choshi M, Nakamura T, Michihara A
Abstract
Reduced serum cholesterol content was recently reported to be one of the factors responsible for cerebral haemorrhage. Stroke-prone spontaneously hypertensive rats (SHRSP) are known to have lower serum cholesterol content than normotensive Wistar-Kyoto rats (WKY). We previously reported that lower levels of mevalonate pyrophosphate decarboxylase (MPD) an...
Source: Clinical and Experimental Pharmacology and Physiology - October 5, 2019 Category: Drugs & Pharmacology Authors: Matsuoka H, Uchino Y, Choshi M, Nakamura T, Michihara A Tags: Clin Exp Pharmacol Physiol Source Type: research
Safety and efficacy of tirofiban in acute ischemic stroke patients not receiving endovascular treatment: a systematic review and meta-analysis.
Conclusions regarding improvement in functional improvement cannot be drawn. Further trials are needed to strengthen the evidence on this topic.
PMID: 32096199 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Early predictive blood markers of hemorrhagic stroke - influence of cytoflavin therapy.
This study aimed to determine early changes in the parameters of oxidative stress and routine biochemistry blood tests in patients with HS and to assess their relationship with clinical outcome. The effects of early applied cytoflavin were also investigated. The prospective study included 151 patients with HS. 48% of patients in the standard conservative therapy was added cytoflavin antioxidant energy therapy from the first day of hospitalization. The neurological status, neuroimaging, biochemical blood tests and free radical processes were assessed on days 1, 5, 10, 20 of hospitalization. In patients with HS, an imbalance...
Source: Canadian Journal of Physiology and Pharmacology - September 9, 2020 Category: Drugs & Pharmacology Authors: Silina E, Rumyantceva SA, Stupin VA, Parfenov VA, Bolevich S Tags: Can J Physiol Pharmacol Source Type: research
Chinese Herbal Medicine Xingnaojing Injection for Acute Ischemic Stroke: An Overview of Systematic Reviews and Meta-Analyses
Conclusion: XNJ appears to be effective and safe for acute IS in improving the neurological deficits, but the evidence is not robust enough. However, whether administering XNJ immediately after or within 24 h of IS is best remains unknown due to the lack of data. Well-designed large-scale randomized controlled trials with measurable outcomes are required in future studies.
Source: Frontiers in Pharmacology - May 18, 2021 Category: Drugs & Pharmacology Source Type: research
Circadian rhythm and risk of hemorrhagic transformation after acute ischemic stroke treated with intravenous thrombolysis - a systematic review
CONCLUSIONS: ICH occurred after ivT seems to follow a circadian pattern; the 18:00-00:00 time frame was the safest one, patients with AIS onset or ivT time between these hours had the lowest incidence of any ICH, including sICH. The 06:00-12:00 block was associated with the highest incidence of ICH and sICH. However, the analysis is limited by the small number of included studies and the heterogeneous findings reported. Further homogenized studies using comparable time frames and sICH definitions are needed to demonstrate this circadian pattern. The review protocol was registered in the OSF database under reference UHNF, d...
Source: CNS and Neurological Disorders Drug Targets - October 6, 2022 Category: Drugs & Pharmacology Authors: Adina Stan Hanna Dragos Stefan Strilciuc Silvina Ilut Vitalie Vacaras Angela Cozma Paul Stefan Panaitescu Horatiu Stan Dafin F Muresanu Source Type: research
