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Intra-arterial treatment of patients with acute ischemic stroke and internal carotid artery occlusion: a literature review
Conclusions This review shows that, for patients with AIS due to an extracranial and/or intracranial ICA occlusion, stenting and mechanical thrombectomy are associated with higher recanalization rates and improved functional outcomes compared with IA thrombolysis.
Source: Journal of NeuroInterventional Surgery - December 11, 2014 Category: Neurosurgery Authors: Kappelhof, M., Marquering, H. A., Berkhemer, O. A., Majoie, C. B. L. M. Tags: Ischemic stroke Source Type: research

Endovascular treatment for M2 occlusions in the era of stentrievers: a descriptive multicenter experience
Conclusions Endovascular treatment of M2 MCA occlusion with stentrievers seems safe. Induced recanalization may double the chances of achieving a favorable outcome, especially for patients with moderate or severe deficit.
Source: Journal of NeuroInterventional Surgery - March 12, 2015 Category: Neurosurgery Authors: Flores, A., Tomasello, A., Cardona, P., de Miquel, M. A., Gomis, M., Garcia Bermejo, P., Obach, V., Urra, X., Marti-Fabregas, J., Canovas, D., Roquer, J., Abilleira, S., Ribo, M., on behalf of the Catalan Stroke Code and Reperfusion Consortium (Cat-SCR) Tags: Ischemic stroke Source Type: research

M2 occlusions as targets for endovascular therapy: comprehensive analysis of diffusion/perfusion MRI, angiography, and clinical outcomes
Conclusions If suitable as targets of ET, M2 occlusions should be given the same consideration as M1 occlusions.
Source: Journal of NeuroInterventional Surgery - June 11, 2015 Category: Neurosurgery Authors: Sheth, S. A., Yoo, B., Saver, J. L., Starkman, S., Ali, L. K., Kim, D., Gonzalez, N. R., Jahan, R., Tateshima, S., Duckwiler, G., Vinuela, F., Liebeskind, D. S., for the UCLA Comprehensive Stroke Center Tags: Ischemic stroke Source Type: research

Asymptomatic moderate carotid artery stenosis with intraplaque hemorrhage: onset of new ischemic stroke
Conclusions Whether plaques with severe stenosis already had severe stenosis at the onset of events or plaques with moderate stenosis progressed owing to an acute change, such as growth of an IPH, remains unclear, because no carotid imaging was carried out just before the events. This is the first case report which presents neurological symptoms and MRI at both baseline and follow-up in patients with asymptomatic moderate carotid artery stenosis and carotid IPH.
Source: Journal of NeuroInterventional Surgery - January 13, 2016 Category: Neurosurgery Authors: Yamada, K., Kawasaki, M., Yoshimura, S., Sasaki, Y., Nakahara, S., Sato, Y. Tags: Ischemic stroke Source Type: research

Comprehensive analysis of intra-arterial treatment for acute ischemic stroke due to cervical artery dissection
Conclusions IAT is a valid alternative therapeutic option for AIS caused by CeAD due to the low complication rate and excellent outcomes observed in this study.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Jensen, J., Salottolo, K., Frei, D., Loy, D., McCarthy, K., Wagner, J., Whaley, M., Bellon, R., Bar-Or, D. Tags: Open access, Ischemic stroke Source Type: research

Local anesthesia as a distinct comparator versus conscious sedation and general anesthesia in endovascular stroke treatment: a systematic review and meta-analysis
Conclusion LA without sedation was not significantly superior to CS or GA in improving outcomes when performing EVT for AIS. However, the quality of the included studies impaired interpretation, and inclusion of an LA arm in future well designed multicenter, randomized controlled trials is warranted.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Butt, W., Dhillon, P. S., Podlasek, A., Malik, L., Nair, S., Hewson, D., England, T. J., Lenthall, R., McConachie, N. Tags: Ischemic stroke Source Type: research

Device size selection can enhance Y-stentrieving efficacy and safety as a rescue strategy in stroke thrombectomy
Conclusion Y-stentrieving is an effective and safe bail-out strategy for refractory bifurcation clots. Longer stents may promote better angiographic outcomes, whereas avoidance of disproportionately large retrievers may mitigate intracranial hemorrhage. Future studies should account for these factors when evaluating alternative stentriever techniques.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Cabral, L. S., MontAlverne, F., Silva, H. C., Passos Filho, P. E., Magalhaes, P. S. C., Bianchin, M. M., Nogueira, R. G. Tags: Ischemic stroke Source Type: research

Non-contrast head CT alone for thrombectomy in acute ischemic stroke: analysis of the ANGEL-ACT registry
Conclusions In patients selected for MT using NCHCT alone versus NCHCT + NVI, there were improved procedural outcomes and smaller increases in baseline mRS scores at 90 days.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Ren, Z., Ma, G., Mokin, M., Jadhav, A. P., Jia, B., Tong, X., Bauer, C., Liu, R., Wang, A., Zhang, X., Mo, D., Ma, N., Gao, F., Song, L., Sun, X., Huo, X., Deng, Y., Liu, L., Luo, G., Luo, X., Peng, Y., Gui, L., Song, C., Wu, J., Wang, L., Li, C., Jovin, Tags: Ischemic stroke Source Type: research

Real-world outcomes associated with the use of the EmboTrap revascularization device for ischemic stroke in the United States
Conclusions This is the first study in the US to report real-world outcomes sourced by retrospective database analysis among patients with AIS undergoing MT using the EmboTrap device. Further research is needed to better understand performance of the EmboTrap device in real-world settings.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Brinjikji, W., Ikeme, S., Kottenmeier, E., Khaled, A., M, S., Khanna, R. Tags: Ischemic stroke Source Type: research

Endovascular thrombectomy versus standard medical treatment for stroke patients with acute basilar artery occlusion: a systematic review and meta-analysis
Conclusion Among patients with BAO, EVT and SMT did not differ significantly in achieving favorable functional outcomes at 3 months, but BAO patients treated with EVT might have lower mortality at 3 months. RCTs are warranted to further assess the efficacy and safety of EVT for BAO patients.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Zhao, Y., Zhao, W., Guo, Y., Li, Y. Tags: Ischemic stroke Source Type: research

Impact of leukoaraiosis in patients with acute ischemic stroke treated with thrombectomy: a post hoc analysis of the DIRECT-MT trial
Conclusion Patients with leukoaraiosis with AIS due to large vessel occlusion are at increased risk of a poor functional outcome after IAT but demonstrate similar sICH rates, and IVT preceding IAT does not increase the risk of sICH in Chinese patients with leukoaraiosis.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Yi, T., Zhang, Y., Chen, W.-h., Wu, Y.-m., Lin, D.-l., Lin, X.-h., Zhang, L., Xing, P.-f., Li, T., Zhang, Y., Wang, S., Yang, P., Cai, M.-z., Liu, J., On behalf of for the DIRECT-MT Investigators Tags: Ischemic stroke Source Type: research

Endovascular treatment of acute ischemic stroke in patients with pre-morbid disability: a meta-analysis
Conclusion In eligible patients with pre-morbid disability, observational studies suggest that EVT carries a higher chance of return to baseline mRS compared with patients treated with MM or without pre-morbid disability, although with higher mortality than patients without pre-morbid disability. These findings argue against the routine exclusion of such patients from EVT and merit validation with randomized trials.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Bala, F., Beland, B., Mistry, E., Almekhlafi, M. A., Goyal, M., Ganesh, A. Tags: Ischemic stroke Source Type: research

Post-reperfusion hyperperfusion after endovascular stroke treatment: a prospective comparative study of TCD versus MRI
Conclusions TCD is a reliable bedside tool to identify post-reperfusion hyperperfusion, correlates well with perfusion MRI, and indicates risk of reperfusion injury after MT.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Kneihsl, M., Hinteregger, N., Nistl, O., Deutschmann, H., Horner, S., Poltrum, B., Fandler-Höfler, S., Hatab, I., Haidegger, M., Pinter, D., Pichler, A., Willeit, K., Knoflach, M., Enzinger, C., Gattringer, T. Tags: Ischemic stroke Source Type: research

Endovascular therapy for acute ischemic stroke in patients with active malignancy: a meta-analysis with trial sequential analysis
Conclusion Although a quarter of patients with active malignancy and AIS regained functional independence, physicians and patients should consider whether to apply EVT in patients with active malignancy.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Jhou, H.-J., Yang, L.-Y., Chen, P.-H., Lee, C.-H. Tags: Ischemic stroke Source Type: research

E-021 Pathophysiology, stroke types, collateral formation and aneurysms in moyamoya disease/moya moya syndrome
ConclusionsMMD is presented most commonly with ischemic stroke in the pediatric age group and with hemorrhagic stroke in the adult age group. MMD-associated intracranial aneurysms frequently occur in patients presenting with hemorrhagic unilateral MMD and are associated with an extremely high rate of rupture. Long-standing hemodynamic stress might contribute to the formation of an aneurysm.Disclosures S. Ahmad: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ahmad, S. Tags: Electronic poster abstracts Source Type: research

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