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Influence of glucose levels on clinical outcome after mechanical thrombectomy for large-vessel occlusion: a systematic review and meta-analysis
Mechanical thrombectomy (MT) represents the mainstay of treatment for patients with acute ischemic stroke due to large-vessel occlusion (LVO). Intravenous thrombolysis has been associated with worse clinical outcome in patients presenting with high blood glucose levels at admission; to date the true effect of hyperglycemia in the setting of MT has not been fully elucidated. In this meta-analysis, we analyzed the influence of high blood glucose levels at admission on clinical outcome after MT. Ovid EMBASE, PubMed, Scopus, and Cochrane Library databases were searched from their dates of inception up to March 2021. An initial...
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Perez-Vega, C., Domingo, R. A., Tripathi, S., Ramos-Fresnedo, A., Kashyap, S., Quinones-Hinojosa, A., Lin, M. P., Fox, W. C., Tawk, R. G. Tags: Ischemic stroke Source Type: research

Direct endovascular treatment versus bridging therapy in patients with acute ischemic stroke eligible for intravenous thrombolysis: systematic review and meta-analysis
Conclusion Compared with bridging therapy, direct EVT may be equally effective and yield a lower rate of ICH and clot migration in patients with AIS. Trail registration number PROSPERO: CRD42021236691.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Zhang, J., Chen, S., Shi, S., Zhang, Y., Kong, D., Xie, Y., Deng, X., Tang, J., Luo, J., Liang, Z. Tags: Vascular neurology Source Type: research

Effectiveness and safety of endovascular thrombectomy for large versus medium vessel occlusions: a single-center experience
Conclusion The 90-day mRS and rate of periprocedural complications were not significantly different between patients treated for LVO and those treated for MeVO with EVT. Older age, not receiving r-tPA, and larger infarct size were independent predictors of poor outcome at 90 days.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Shek, K., Alcock, S., Ghrooda, E., Trivedi, A., McEachern, J., Kaderali, Z., Shankar, J. Tags: Ischemic stroke Source Type: research

Embotrap Extraction & Clot Evaluation & Lesion Evaluation for NeuroThrombectomy (EXCELLENT) Registry design and methods
Conclusions The EXCELLENT registry will provide reproducible effectiveness and safety data of EmboTrap for its use for mechanical thrombectomy. Additionally, the study will characterize the blood clots retrieved during mechanical thrombectomy with respect to their composition and histopathological analysis and potential correlations with clinical and imaging findings. Trial registration number NCT03685578.
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Siddiqui, A. H., Waqas, M., Brinjikji, W., De Meyer, S. F., Doyle, K., Fiehler, J., Hacke, W., Hanel, R. A., Jovin, T. G., Liebeskind, D. S., Yoo, A. J., Zaidat, O. O., Andersson, T., Nogueira, R. G. Tags: Open access, Ischemic stroke Source Type: research

E-145 Collateral patterns in large vessel occlusion stroke and outcomes after endovascular thrombectomy
ConclusionsCollateral pattern is a robust determinant of 90-day outcomes after EVT. It may help guide EVT decisions in the delayed window, especially when there are delays to treatment such as those related to patient transfer. Further prospective studies are needed to evaluate the role of collateral pattern in treatment decisions and prognostication.Disclosures R. Regenhardt: None. M. Lev: None. J. He: None. A. Dmytriw: None. J. Vranic: None. J. Rabinov: None. C. Stapleton: None. A. Patel: None. A. Singhal: None. G. Gonzalez: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Regenhardt, R., Lev, M., He, J., Dmytriw, A., Vranic, J., Rabinov, J., Stapleton, C., Patel, A., Singhal, A., Gonzalez, G. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-222 How far is too far in stroke thrombectomy? from xl to xs vessel occlusions with radially adjustable stent-retrievers - tigertriever xl and tigertriever 13
ConclusionMechanical thrombectomy for both primary or secondary DMVO seems feasible and as safe as for LVO. Our initial experience using the Tigertriever13 is of special interest as it shows we can potentially significantly expand AIS population that can benefit from mechanical thrombectomy treatment.Disclosures A. Guenego: None. B. Lubicz: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Unexplained early neurological deterioration after endovascular treatment for acute large vessel occlusion: incidence, predictors, and clinical impact: Data from ANGEL-ACT registry
Conclusions ENDunexplained associated with poor 90day outcomes occurred in 4.3% of patients with acute LVO undergoing EVT. Several independent predictors of ENDunexplained were identified in this study, which should be considered in daily practice to improve acute LVO management. Clinical trial Registration http://wwwclinicaltrialsgov NCT03370939.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Sun, D., Tong, X., Huo, X., Jia, B., Raynald, , Wang, A., Ma, G., Ma, N., Gao, F., Mo, D., Song, L., Sun, X., Liu, L., Deng, Y., Li, X., Wang, B., Luo, G., Wang, Y., Miao, Z., On behalf of the ANGEL-ACT study group Tags: Ischemic stroke Source Type: research

Diversion-p64: results from an international, prospective, multicenter, single-arm post-market study to assess the safety and effectiveness of the p64 flow modulation device
Conclusions Diversion-p64 is the largest prospective study using the p64 flow modulation device. The results of this study demonstrate that the device has a high efficacy and carries a low rate of mortality and permanent morbidity.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Bonafe, A., Perez, M. A., Henkes, H., Lylyk, P., Bleise, C., Gascou, G., Sirakov, S., Sirakov, A., Stockx, L., Turjman, F., Petrov, A., Roth, C., Narata, A.-P., Barreau, X., Loehr, C., Berlis, A., Pierot, L., Mis, M., Goddard, T., Clifton, A., Klisch, J., Tags: Open access, Hemorrhagic stroke Source Type: research

P72 NeVa™ thrombectomy device (NvTD): initial experience in a regional argentinian stroke care center
ConclusionsThe NvTD showed high First Pass and overall recanalization rates. Even though a safety profile was observed, further investigation regarding this item are needed.ReferencesRibo M, Requena M, Macho J, et al. Mechanical thrombectomy with a novel stent retriever with multifunctional zones: initial clinical experience with the Neva™ thrombectomy device. J Neuroradiol 2020;47:301–305.Goyal M, Menon BK, Van Zwam WH, et al. Hermes collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:1723–17...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Petra, F., Caballero, G., Grana, M., Fernandez, C., Alvarado, L., Gonzalez, M., Nazar, F., Horvath, F., Galiana, G., Genco, J., Parra, L. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P78 How far is too far in stroke thrombectomy? From XL to XS vessel occlusions with radially adjustable stent-retrievers - Tigertriever XL and Tigertriever 13
ConclusionMechanical thrombectomy for both primary or secondary DMVO seems feasible and as safe as for LVO. Our initial experience using the Tigertriever13 is of special interest as it shows we can potentially significantly expand AIS population that can benefit from mechanical thrombectomy treatment.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementCons...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P80 Aspiration thrombectomy of acute ischemic stroke patients with anterior circulation tandem lesion
ConclusionsAspiration thrombectomy restored blood flow and resulted in good 90-day functional outcome in AIS patients with anterior circulation tandem lesion. The 90-day mortality rate in these patients was low. Clinical outcomes were similar between patients with and without stent. Do you have any conflict of interest to declare?: YesConflict of Interest Statement Zaidat: Grant/research support: Genentech, Medtronic Neurovascular, Stryker; Consultant: Codman, Medtronic Neurovascular, National Institutes of Health (NIH) StrokeNet, Penumbra, Stryker. Other financial or material support: Honoraria: Codman, Medtronic Neurovas...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Zaidat, O., Fifi, J., Hassan, A. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Impact of anesthetic strategy on outcomes for patients with acute basilar artery occlusion undergoing mechanical thrombectomy
Conclusions The choice of anesthetic strategy, GA, LA, or CS, did not affect the clinical outcomes of patients with acute BAO treated with MT in the BASILAR registry.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Li, F., Wan, J., Song, J., Yuan, J., Kong, W., Huang, J., Luo, W., Wu, D., Li, L., Chen, L., Zhao, C., Chen, J., Tao, H., Sang, H., Qiu, Z., Zi, W., Yang, Q., Chen, X., Li, H., Peng, F. Tags: Ischemic stroke Source Type: research

Obstructive sleep apnea confers lower mortality risk in acute ischemic stroke patients treated with endovascular thrombectomy: National Inpatient Sample analysis 2010-2018
Conclusions Our findings suggest that MT is a viable and safe treatment option for AIS patients with OSA.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Lapow, J. M., Dicpinigaitis, A. J., Pammal, R. S., Coghill, G. A., Rechester, O., Feldstein, E., Nuoman, R., Maselli, K., Kodi, S., Bauerschmidt, A., Rosenberg, J. B., Yaghi, S., Kaur, G., Kurian, C., Chong, J. Y., Mayer, S. A., Gandhi, C. D., Al-Mufti, F Tags: Vascular neurology Source Type: research

Effect of intravenous thrombolysis before endovascular therapy on outcome according to collateral status: insight from the ETIS Registry
Conclusions Collateral status does not modify the effect of pretreatment IVT on the efficacy and safety outcomes of EVT.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Anadani, M., Januel, A.-C., Finitsis, S., Clarencon, F., Richard, S., Marnat, G., Bourcier, R., Sibon, I., Dargazanli, C., Arquizan, C., Blanc, R., Lapergue, B., Consoli, A., Eugene, F., Vannier, S., Caroff, J., Denier, C., Boulanger, M., Gauberti, M., Ro Tags: Ischemic stroke Source Type: research

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