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P005/44 Using the pEGASUS-stent with antithrombogenic properties and single antiplatelet therapy in a case of thrombectomy
IntroductionRescue stenting is used more and more in stroke cases with large-vessel-occlusion or medium-vessel-occlusion refractory to mechanical thrombectomy. The pEGASUS-stent(Phenox) represents a device which is equipped with a hydrophilic polymer coating(HPC) with antithrombogenic properties. The coating allows for implantation under single antiplatelet therapy, thus possibly reducing the risk of bleeding in acute stroke cases.Case HistoryA 79-year-old woman was rushed to emergency room due to left-sided hemiparesis and National-Institutes-of-Health-Stroke-Scale(NIHSS) of 14. Computed-tomography-image showed an occlusi...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Krug, N., Schulze-Zachau, V., Ntoulias, N., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

P160/223 Acute stroke with treatment of tandem lesions under triple antiplatelet therapy: procedural saftey, stent patency and outcome at 90 days
ConclusionTL treatment under triple AP was safe in our experience, resulting in a low rate of restenosis and with favorable outcome in 92%. The influence of comorbidities on restenosis could be negligible within the described follow-up period.Disclosure of InterestPhilipp von Gottberg: Nothing to disclose.Ali Khanafer: Nothing to discloseVictoria Hellstern: Proctering for phenox GmbH.Alexandru Cimpocca: Nothing to disclose.Hans Henkes: Proctoring for phenox GmbH, Co-Founder and Co-Owner of CONTARA GmbH
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Philipp, V. G., Khanafer, A., Hellstern, V., Cimpoca, A., Bäzner, H., Henkes, H. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

Endovascular recanalization of complete subacute to chronic atherosclerotic occlusions of intracranial arteries
Conclusions Endovascular recanalization can be performed with an acceptable safety profile in selected patients with symptomatic complete subacute to chronic intracranial atherosclerotic occlusion. Additional studies are warranted to investigate whether this treatment compares favorably with best medical management.
Source: Journal of NeuroInterventional Surgery - October 7, 2014 Category: Neurosurgery Authors: Aghaebrahim, A., Jovin, T., Jadhav, A. P., Noorian, A., Gupta, R., Nogueira, R. G. Tags: Editor''s choice, Ischemic stroke Source Type: research

O-034 Carotid Artery Angioplasty versus Stenting in Acute Ischemic Stroke
Conclusions This data suggest that patients undergoing angioplasty alone in the setting of acute internal carotid artery occlusion may have improved functional outcome at 90-day compared to those undergoing stenting. This study was limited by a small sample size and a larger study would be needed to confirm these findings. Keywords angioplasty, stenting, acute ischemic stroke, carotid occlusion. Disclosures O. Choudhri: None. M. Gupta: None. A. Feroze: None. G. Albers: None. M. Lansberg: None. H. Do: None. R. Dodd: None. M. Marcellus: None. M. Marks: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Choudhri, O., Gupta, M., Feroze, A., Albers, G., Lansberg, M., Do, H., Dodd, R., Marcellus, M., Marks, M. Tags: Oral abstracts Source Type: research

P-017 M2 Occlusions as a Target for Endovascular Therapy: Comprehensive Analysis of Diffusion/Perfusion MRI, Angiography, and Clinical Outcomes
Conclusion In patients undergoing ERT compared to those with M1 occlusions, patients with M2 occlusions presented with smaller infarcts and developed less haemorrhage. In patients with M2 occlusions, successful reperfusion with ERT was associated with smaller final infarcts, decreased infarct expansion, and improved clinical outcomes. IV tPA was not sufficient in recanalizing many M2 occlusions. Patients with M2 occlusions benefit from ERT when tPA cannot be given or has failed to recanalise the vessel. Disclosures S. Sheth: None. J. Saver: None. R. Jahan: None. S. Starkman: None. G. Duckwiler: None. S. Tateshima: None. N...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Sheth, S., Saver, J., Jahan, R., Starkman, S., Duckwiler, G., Tateshima, S., Gonzalez, N., Liebeskind, D., Stroke Investigators, U. Tags: Oral poster abstracts Source Type: research

E-005 primary acute stroke thrombectomy within 3 hours from large artery occlusion (past3-lao) - a pilot study
Conclusion: Our pilot study demonstrates that primary thrombectomy using SRT in AIS due to a LAO is not only safe and feasible, but associated with acceptable recanalization resulting in exceptional good functional outcome. Larger randomized controlled studies are needed.DisclosuresY. Lodi: None. Y. Lodi: None. V. Reddy: None. A. Devasenapathy: None. G. Petro: None. A. Hourani: None. C. Chou: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Lodi, Y., Lodi, Y., Reddy, V., Devasenapathy, A., Petro, G., Hourani, A., Chou, C. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

O-004 Analysis of M2 Occlusions within TREVO Acute Ischemic Stroke (TRACK) stent-retriever Thrombectomy Registry
ConclusionsPatients with M2 Occlusions are more likely to achieve complete recanalization from the first pass with Trevo stent retriever device than M1 occlusion. In addition, the M2 cohort had a numerically higher rate of good clinical outcome and less rate of mortality than M1 group. This substudy is limited by lack of a control M2 group without mechanical thrombectomy.DisclosuresA. Castonguay: None. R. Nogueira: None. J. English: None. S. Satti: None. H. Farid: None. E. Veznedaroglu: None. M. Binning: None. A. Puri: None. N. Vora: None. R. Budzik: None. G. Dabus: None. I. Linfante: None. V. Janardhan: None. A. Alshekhle...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Castonguay, A., Nogueira, R., English, J., Satti, S., Farid, H., Veznedaroglu, E., Binning, M., Puri, A., Vora, N., Budzik, R., Dabus, G., Linfante, I., Janardhan, V., Alshekhlee, A., Abraham, M., Edgell, R., Taqi, M., El Khoury, R., Mokin, M., Mokin, M., Tags: Oral abstracts Source Type: research

Final results of the US humanitarian device exemption study of the low-profile visualized intraluminal support (LVIS) device
Conclusions The LVIS device facilitated the coil embolization of wide-necked intracranial aneurysms with high rates of technical success, an excellent safety profile, and very high rates of complete and near-complete occlusion at follow-up. Trial registration number NCT01541254.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Fiorella, D., Arthur, A., Boulos, A., Diaz, O., Jabbour, P., Pride, L., Turk, A. S., Woo, H. H., Derdeyn, C., Millar, J., Clifton, A. Tags: Editor''s choice, Hemorrhagic stroke Source Type: research

Intracerebral hemorrhage: the next frontier for minimally invasive stroke treatment
Great technical, scientific, and clinical advances have been made in the treatment of both emergent large vessel occlusions (ELVOs) and cerebral aneurysms. However, little progress has been made in the management of patients with primary intracerebral hemorrhage (ICH)—the leading cause of hemorrhagic stroke.1 ICH accounts for 10–15% of all strokes and is associated with the highest rates of morbidity and mortality of all stroke subtypes.1 2 Almost half of afflicted patients do not survive and only 20% of survivors are independent at 180 days.3 4 No medical interventions, with the exception of blood pressur...
Source: Journal of NeuroInterventional Surgery - September 12, 2016 Category: Neurosurgery Authors: Fiorella, D., Mocco, J., Arthur, A. Tags: Editor ' s column Source Type: research

Thromboaspiration technique as first approach for endovascular treatment of acute ischemic stroke: initial experience at nine Italian stroke centers
Conclusions Direct aspiration thrombectomy appears a feasible technique with good revascularization results achieved in more than half the patients. In light of the self-reported data, inhomogeneous patient selection, absence of a core imaging laboratory, and a non-standardized approach, the results should be validated in a larger trial.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Romano, D. G., Cioni, S., Vinci, S. L., Pero, G., Comelli, C., Comai, A., Peschillo, S., Mardighian, D., Castellan, L., Resta, F., Piano, M. G., Comelli, S., Barletta, L., Puliti, A., Leonini, S., Bracco, S. Tags: Ischemic stroke Source Type: research

Endovascular treatment in the acute and non-acute phases of carotid dissection: a therapeutic approach
Conclusions Endovascular treatment of selected cases of patients with CD associated with thromboembolic events and hemodynamic failure after unsuccessful medical therapy is a safe and effective method of restoring vessel lumen integrity, with good short-term clinical evolution.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Delgado, F., Bravo, I., Jimenez, E., Murias, E., Saiz, A., Vega, P., Lopez-Rueda, A., Blasco, J., Macho, J., Gonzalez, A. Tags: Ischemic stroke Source Type: research

Management and outcome of spontaneous cerebral venous sinus thrombosis in a 5-year consecutive single-institution cohort
Conclusions In our series, the majority (92.9%) of patients with spontaneous dural sinus thrombosis had a favorable clinical outcome as defined by a mRS ≤2. Further prospective studies are needed to study the impact of anticoagulation on the clinical course of the disease.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Lee, D. J., Ahmadpour, A., Binyamin, T., Dahlin, B. C., Shahlaie, K., Waldau, B. Tags: Hemorrhagic stroke Source Type: research

Delayed subarachnoid hemorrhage 7 years after cerebellar infarction from traumatic vertebral artery dissection
Vertebral artery dissection (VAD) is an important cause of ischemic stroke and subarachnoid hemorrhage (SAH). Dissections presenting with ischemia rarely cause SAH after more than a few hours, especially without radiographic evidence of pseudoaneurysm. We successfully treated a patient for persistent vessel injury presenting with SAH 7 years after presenting with extracranial subocclusive dissection of the right vertebral artery and an associated right posterior inferior cerebellar artery stroke. This is one of only three reported cases of delayed SAH occurring more than 2 weeks after an initial ischemic presenta...
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Silva, M. A., See, A. P., Khandelwal, P., Patel, N. J., Aziz-Sultan, M. A. Tags: Hemorrhagic stroke Source Type: research

Endovascular treatment for AIS with underlying ICAD
Conclusions Despite AIS with underlying ICAD requiring a more complex, technically demanding recanalization strategy than traditional thromboembolic AIS, it appears safe, and good outcomes are obtainable.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Al Kasab, S., Almadidy, Z., Spiotta, A. M., Turk, A. S., Chaudry, M. I., Hungerford, J. P., Turner, R. D. Tags: Ischemic stroke Source Type: research

Impact of eloquent motor cortex-tissue reperfusion beyond the traditional thrombolysis in cerebral infarction (TICI) scoring after thrombectomy
Conclusions Eloquent PMC-tissue reperfusion is a key determinant of functional outcome, with a greater impact than volume-based (TICI) degree of partial reperfusion alone. PMC-targeted revascularization among patients with partial reperfusion may further diminish post-stroke disability after EVT.
Source: Journal of NeuroInterventional Surgery - October 15, 2021 Category: Neurosurgery Authors: Raychev, R., Saber, H., Saver, J. L., Hinman, J. D., Brown, S., Vinuela, F., Duckwiler, G., Jahan, R., Tateshima, S., Szeder, V., Nour, M., Colby, G. P., Restrepo, L., Kim, D., Bahr-Hosseini, M., Ali, L., Starkman, S., Rao, N., Nogueira, R. G., Liebeskind Tags: Open access, Ischemic stroke Source Type: research

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