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Condition: Hemorrhagic Stroke
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Total 297 results found since Jan 2013.

An analysis of after hours MRI scans in a busy tertiary hospital neuro intensive care unit-Does your patient safety is at jeopardy? (P7.326)
CONCLUSIONS: Based on the above results we are in the process of developing selective patient defined criteria for performing after hours MRI scan in the ICU as an important quality measure to improve patient's safety.We highly recommend all hospitals to take such initiatives to improve patient's safety especially in the ICU setting Study Supported by: Disclosure: Dr. Nattanmai Chandrasekaran has nothing to disclose. Dr. Shutter has received personal compensation for activities with Johnson & Johnson/Codman and UCB Pharma as a consultant and/or speaker.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nattanmai Chandrasekaran, P., Shutter, L. Tags: Practice, Policy, and Ethics Source Type: research

Predictors of Poor Outcome in Bacterial Meningitis: Retrospective Analysis of Nationwide Inpatient Sample (P5.046)
CONCLUSIONS: In this retrospective study, every decade increase in age, teaching hospital status and development of complications like hydrocephalus, ischemic stroke, seizures, intracranial abscess and respiratory failure were predictors of poor outcome. Every calendar year increase was a negative predictor of poor outcome. Study Supported by:Disclosure: Dr. Dharaiya has nothing to disclose. Dr. Modi has nothing to disclose. Dr. Maraka has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dharaiya, D., Modi, S., Maraka, S. Tags: Neuroepidemiology: Headache, Global Health, and Infectious Disease Source Type: research

Mortality Predictors in Bacterial Meningitis Patients who developed Hydrocephalus (P5.050)
CONCLUSIONS: In this retrospective analysis, we found that every decade increase in age, ischemic stroke, respiratory failure and requirement of ventriculostomy were significant predictors of mortality in patients of bacterial meningitis who developed hydrocephalus. Study Supported by:Disclosure: Dr. Irshad has nothing to disclose. Dr. Modi has nothing to disclose. Dr. Naqvi has nothing to disclose. Dr. Dharaiya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Irshad, K., Modi, S., Naqvi, I., Dharaiya, D. Tags: Neuroepidemiology: Headache, Global Health, and Infectious Disease Source Type: research

Safety of intravenous thrombolysis for acute ischaemic stroke including concomitant neoplastic disease sufferers – experience from Poland
ConclusionIntravenous thrombolysis performed in Caucasian stroke patients with past or current neoplastic diseases, but not in the course of chemo‐ and radiotherapy, can be a safe and effective method of treatment. In making decision on the thrombolytic treatment, the risk of bleeding complications and the life expectancy should be assessed.
Source: International Journal of Clinical Practice - February 27, 2015 Category: Internal Medicine Authors: P. Sobolewski, W. Brola, W. Szczuchniak, M. Fudala, A. Sobota Tags: Original Paper Source Type: research

In-hospital outcomes of thrombolysis for acute ischemic stroke in patients with primary brain tumors
Publication date: March 2015 Source:Journal of Clinical Neuroscience, Volume 22, Issue 3 Author(s): Santosh B. Murthy , Yogesh Moradiya , Shreyansh Shah , Aditi Shastri , Eric M. Bershad , Jose I. Suarez Data on thrombolysis outcomes in patients with primary brain tumors are limited. Our aim was to study stroke outcomes following thrombolysis in these patients in a population-based study. Patients with acute ischemic stroke who received thrombolysis were identified from the 2002–2011 USA Nationwide Inpatient Sample. We compared demographics, comorbidities, and outcomes between primary brain tumor-associated strokes (BT...
Source: Journal of Clinical Neuroscience - February 16, 2015 Category: Neuroscience Source Type: research

5 Scary Symptoms That Are Usually Harmless
SPECIAL FROM Next Avenue By Linda Melone After 50, aches, pains and the occasional muscle twinge become a fact of life. But some symptoms that may seem frightening or serious turn out to be far less than they appear. While you should always see a doctor if you experience something out of the ordinary, these signs generally are more smoke than fire: A Bloody Nose Nosebleeds can be particularly frightening due to the suddenness in which they occur and the sometimes large amount of blood involved. “People worry that it’s internal bleeding, but almost every time it’s not,” says Dr. Carlo Reyes, emergency room...
Source: Healthy Living - The Huffington Post - February 5, 2015 Category: Consumer Health News Source Type: news

Intratumoral Hemorrhage in a Patient with Malignant Meningioma under Anticoagulant Therapy
We report the case of an elderly woman with malignant meningioma and atrial fibrillation who started taking anticoagulants after an ischemic stroke and subsequently developed intratumoral hemorrhage. Further studies are required to confirm whether a particular anticoagulant agent is suitable for patients with brain tumor and atrial fibrillation.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2015 Category: Neurology Authors: Yasuyuki Ito, Makoto Nakajima, Mari Watari, Tetsuro Sakamoto, Yoichiro Hashimoto, Seiji Tajiri, Akira Takada, Yukio Ando Tags: Case Report Source Type: research

Cn-15 * adverse effects of bevacizumab in brain tumor patients
CONCLUSION: The range of toxicities was similar to other reports. Interestingly, hypertension was the most common adverse effect and was often not treated. The high incidence of lymphocytopenia may have implications for combination with immunotherapies. These findings underscore the need to develop predictive models to identify patients at high risk for serious treatment-related toxicities.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Pawar, T., Ladha, H., Mandel, J., Gilbert, M., O'Brien, B., Hamza, M., Armstrong, T. Tags: COMPLICATIONS OF THERAPY AND NEUROTOXICITY Source Type: research

Genetic deletion of calcium/calmodulin-dependent protein kinase kinase ß (CaMKK ß) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice
Conclusions: Inhibition of CaMKK signaling exacerbated stroke outcome and increased BBB impairment, transcriptional inactivation and inflammatory responses in females after stroke. Therefore, CaMKK signaling may be a potential target for stroke treatment in both males and females.
Source: BMC Neuroscience - October 21, 2014 Category: Neuroscience Authors: Lin LiuLouise McCulloughJun Li Source Type: research

Intracranial Pressure and Cerebral Perfusion Pressure Monitoring in Non-TBI Patients: Special Considerations
Abstract The effect of intracranial pressure (ICP) and the role of ICP monitoring are best studied in traumatic brain injury (TBI). However, a variety of acute neurologic illnesses e.g., subarachnoid hemorrhage, intracerebral hemorrhage, ischemic stroke, meningitis/encephalitis, and select metabolic disorders, e.g., liver failure and malignant, brain tumors can affect ICP. The purpose of this paper is to review the literature about ICP monitoring in conditions other than TBI and to provide recommendations how the technique may be used in patient management. A PubMed search between 1980 and September 2013 identifie...
Source: Neurocritical Care - September 11, 2014 Category: Neurology Source Type: research

Fatal Intracranial Hemorrhage after Intravenous Thrombolytic Therapy for Acute Ischemic Stroke Associated with Cancer-related Nonbacterial Thrombotic Endocarditis
Nonbacterial thrombotic endocarditis (NBTE) is associated with hypercoagulability in patients with inflammatory states such as cancer and autoimmune diseases. Cardiac vegetations caused by NBTE often lead to life-threatening systemic thromboembolism that most frequently affects the brain, spleen, and kidneys. A 54-year-old woman diagnosed with ovarian cancer suddenly developed back pain and left hemiparesis. Although intravenous alteplase (rt-PA) therapy was administered to treat hyperacute ischemic infarction detected by magnetic resonance imaging, intracranial hemorrhage occurred in the left hemisphere several hours late...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Takuya Yagi, Kie Takahashi, Mariko Tanikawa, Morinobu Seki, Takato Abe, Norihiro Suzuki Tags: Case Reports Source Type: research

The Case Files: Unusual Headache
By Al-Hashimi, Siddhartha DO; Leavens, John MD A 23-year-old woman with a history of migraine headaches presented to the emergency department for a different-than-usual headache. She had a six-day history of intermittent headaches. The onset was at rest, and there was no history of trauma.   The headache was located behind her left eye, and it radiated into the posterior portion of her head. She characterized it as being 8/10 in intensity. Bright lights were reported as an exacerbating factor. The headache was associated with nausea and multiple episodes of emesis. She had 10 episodes of vomiting the evening prior to arri...
Source: The Case Files - June 5, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Should they have a percutaneous endoscopic gastrostomy? The importance of assessing decision-making capacity and the central role of a multidisciplinary team.
Abstract Decisions about percutaneous endoscopic gastrostomy (PEG) can be clinically and ethically challenging, particularly when patients lack decision-making capacity. As the age of the UK population rises, with the associated increase in prevalence of dementias and neurodegenerative diseases, it is becoming an increasingly important issue for clinicians. The recent review and subsequent withdrawal of the Liverpool Care Pathway highlighted feeding as a particular area of concern. The authors undertook a 1-year retrospective review of individuals referred to the feeding issues multidisciplinary team (FIMDT) at Ad...
Source: Clinical Medicine - June 1, 2014 Category: Journals (General) Authors: Clarke G, Galbraith S, Woodward J, Holland A, Barclay S Tags: Clin Med Source Type: research

Inhibition of Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1) Increases Experimental Stroke Injury.
CONCLUSIONS:: We have demonstrated that MKP-1 signaling is an endogenous protective mechanism in stroke. Our data imply that MKP-1 possesses ant-apoptotic and anti-inflammatory properties by simultaneously controlling the activities of JNK and microglial p38. PMID: 24842488 [PubMed - as supplied by publisher]
Source: Experimental Neurology - May 16, 2014 Category: Neurology Authors: Liu L, Doran S, Xu Y, Manwani B, Ritzel R, Benashski S, McCullough L, Li J Tags: Exp Neurol Source Type: research

New Onset Seizures in Elderly:Clinical Presentation and Etiology of First Ever Seizure (P3.235)
CONCLUSIONS: The most common etiology of seizures in elderly was cerebro-vascular disease. Commonest presentation was focal seizureStudy Supported by: nilDisclosure: Dr. Shariff has nothing to disclose. Dr. Alhameed has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shariff, E., Alhameed, M. Tags: Epilepsy and Clinical Neurophysiology: Clinical Manifestations Source Type: research