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Condition: Epilepsy
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Total 100 results found since Jan 2013.
Scientists Are Just Beginning to Understand COVID-19 ’ s Effect On the Brain
Early in the COVID-19 pandemic, doctors started to notice something striking. For what was originally described as a respiratory virus, SARS-CoV-2 seemed to have a strong effect on the brain, causing everything from loss of taste and smell and brain fog to, in serious cases, stroke.
NYU Langone Health, a New York city research hospital, started collating those anecdotes in hopes of better understanding how the virus affects the brain and nervous system. Years later, the project has morphed from focusing solely on acute symptoms to also tracking the long-term neurologic issues that some people with Long COVID experience, sa...
Source: TIME: Health - July 17, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
Neural circuit changes in neurological disorders: Evidence from in vivo two-photon imaging
Ageing Res Rev. 2023 Apr 13;87:101933. doi: 10.1016/j.arr.2023.101933. Online ahead of print.ABSTRACTNeural circuits, such as synaptic plasticity and neural activity, are critical components of healthy brain function. The consequent dynamic remodeling of neural circuits is an ongoing procedure affecting neuronal activities. Disruption of this essential process results in diseases. Advanced microscopic applications such as two-photon laser scanning microscopy have recently been applied to understand neural circuit changes during disease since it can visualize fine structural and functional cellular activation in living anim...
Source: Ageing Research Reviews - April 15, 2023 Category: Genetics & Stem Cells Authors: Huan Xiong Fei Tang Yujie Guo Ruxiang Xu Peng Lei Source Type: research
Neural Circuit Changes in Neurological Disorders: Evidence from in vivo Two-photon Imaging
Ageing Res Rev. 2023 Apr 13:101933. doi: 10.1016/j.arr.2023.101933. Online ahead of print.ABSTRACTNeural circuits, such as synaptic plasticity and neural activity, are critical components of healthy brain function. The consequent dynamic remodeling of neural circuits is an ongoing procedure affecting neuronal activities. Disruption of this essential process results in diseases. Advanced microscopic applications such as two-photon laser scanning microscopy have recently been applied to understand neural circuit changes during disease since it can visualize fine structural and functional cellular activation in living animals...
Source: Ageing Research Reviews - April 15, 2023 Category: Genetics & Stem Cells Authors: Huan Xiong Fei Tang Yujie Guo Ruxiang Xu Peng Lei Source Type: research
Tracers progress for positron emission tomography imaging of glial-related disease
J Biomed Res. 2022 Jun 28:1-15. doi: 10.7555/JBR.36.20220017. Online ahead of print.ABSTRACTGlial cells play an essential part in the neuron system. They can not only serve as structural blocks in the human brain but also participate in many biological processes. Extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. Positron emission tomography is a functional imaging technique providing molecular-level information before anatomic ch...
Source: Biomed Res - September 22, 2022 Category: Research Authors: Haoran Jia Tianwu Xie Source Type: research
011 Progressive myoclonic epilepsy due to rare mitochondrial ND6 mutation, m.14487T>C
We report the case of a 43-year old man with adult-onset drug-resistant epilepsy, cortical myoclonus and bilateral optic neuropathies. Serial MRI scans over a two year period demonstrated the interval devel- opment of bihemispheric stroke-like lesions. Giant somatosensory evoked potentials and short-duration myoclonic jerks with craniocaudal spread on surface-EMG were consistent with cortical myoclonus. Optical coherence tomography showed bilateral symmetric thinning of the nerve fibre layer in the pap- illomacular bundles. Muscle biopsy was non-diagnostic, however next-generation whole mitochondrial gene sequencing identi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 27, 2022 Category: Neurosurgery Authors: Khoo, A., Naidu, S., Wijayendran, S., Merve, A., Bremner, F., Sidhu, M. Tags: Live Poster, 13 May Poster Session 1 Source Type: research
60 Years of Achievements by KSNM in Neuroimaging Research
Nucl Med Mol Imaging. 2022 Feb;56(1):3-16. doi: 10.1007/s13139-021-00727-1. Epub 2022 Jan 15.ABSTRACTNuclear medicine neuroimaging is able to show functional and molecular biologic abnormalities in various neuropsychiatric diseases. Therefore, it has played important roles in the clinical diagnosis and in research on the normal and pathological states of the brain. More than 400 outstanding studies have been conducted by Korean researchers over the past 60 years. In the 1990s, when multiheaded single-photon emission computed tomography (SPECT) scanners were first introduced in South Korea, stroke research using brain perfu...
Source: Molecular Medicine - February 21, 2022 Category: Molecular Biology Authors: Jae Seung Kim Hye Joo Son Minyoung Oh Dong Yun Lee Hae Won Kim Jungsu Oh Source Type: research
A woman in her sixties with epilepsy and syncope
Tidsskr Nor Laegeforen. 2022 Jan 24;142(2). doi: 10.4045/tidsskr.21.0152. Print 2022 Feb 1.ABSTRACTBACKGROUND: A woman in her sixties had been diagnosed with generalised epilepsy twenty years earlier. The diagnosis was confirmed by EEG, and an MRI scan revealed hippocampal sclerosis, which is not uncommon in patients with epilepsy. Treatment with carbamazepine was initiated.CASE PRESENTATION: Due to a rise in the patient's cholesterol, carbamazepine was replaced with oxcarbazepine. At a follow-up, the patient reported a recent episode with loss of consciousness. Unstable epilepsy was suspected and the oxcarbazepine dose in...
Source: Tidsskrift for den Norske Laegeforening - February 2, 2022 Category: General Medicine Authors: Jana Midelfart-Hoff Gregorz Gradek Øystein Wendelbo Bernt Andreas Engelsen Source Type: research
