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Cardiovascular disease and risk factors in adults with diabetes mellitus in Hungary: a population-based study
The objective of this study was to estimate the prevalence of CVD in individuals with DM and to investigate the association between potential risk factors and the presence of CVD among individuals with DM in a population-based sample.MethodsThe study was based on data from three waves of the European Health Interview Surveys (EHIS) conducted in Hungary in 2009, 2014, and 2019.ResultsThe prevalence of CVD among patients with DM decreased during the study period and that socioeconomic factors, cardiometabolic risk factors including high blood pressure and high cholesterol, and depression are major contributors to CVD burden ...
Source: Frontiers in Endocrinology - September 14, 2023 Category: Endocrinology Source Type: research

Neuroendocrine regulation in stroke
Trends Endocrinol Metab. 2023 Mar 13:S1043-2760(23)00036-X. doi: 10.1016/j.tem.2023.02.005. Online ahead of print.ABSTRACTThe neuroendocrine system, a crosstalk between the central nervous system and endocrine glands, balances and controls hormone secretion and their functions. Neuroendocrine pathways and mechanisms often get dysregulated following stroke, leading to altered hormone secretion and aberrant receptor expression. Dysregulation of the hypothalamus-pituitary-thyroid (HPT) axis and hypothalamus-pituitary-adrenal (HPA) axis often led to severe stroke outcomes. Post-stroke complications such as cognitive impairment...
Source: Trends in Endocrinology and Metabolism: TEM - March 15, 2023 Category: Endocrinology Authors: Aishika Datta Chandrima Saha Pratiksha Godse Muskaan Sharma Deepaneeta Sarmah Pallab Bhattacharya Source Type: research

Screening for obstructive sleep apnoea in high-risk patients with mood disorders
CONCLUSIONS: This pilot study showed an increased risk of OSA in patients with mood disorders. Psychiatric patients with identified risk factors should be routinely screened for obstructive sleep apnoea and referred to proper treatment.PMID:36528884
Source: Neuroendocrinology Letters - December 18, 2022 Category: Endocrinology Source Type: research

Sex differences in the blood-brain barrier: implications for mental health
Front Neuroendocrinol. 2022 Mar 7:100989. doi: 10.1016/j.yfrne.2022.100989. Online ahead of print.ABSTRACTPrevalence of mental disorders, including major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies. Growing evidence points toward major sex differences in these conditions, and high rates of treatment resistance support the need to consider novel biological mechanisms outside of neuronal function to gain mechanistic insights that could lead to innovative therapies. Blood-brain barrier alterations have been reported in MDD, BD and SZ. Here, we provi...
Source: Frontiers in Neuroendocrinology - March 10, 2022 Category: Endocrinology Authors: Laurence Dion-Albert Luisa Bandeira Binder Beatrice Daigle Amandine Hong-Minh Manon Lebel Caroline Menard Source Type: research

Prediabetes and risk of mortality, diabetes-related complications and comorbidities: umbrella review of meta-analyses of prospective studies
Conclusions/interpretationPrediabetes was positively associated with risk of all-cause mortality and the incidence of cardiovascular outcomes, CHD, stroke, chronic kidney disease, cancer and dementia. Further high-quality studies, particularly on HbA1c-defined prediabetes and other relevant health outcomes (e. g. neuropathy) are required to support the evidence.Graphical abstract
Source: Diabetologia - January 23, 2022 Category: Endocrinology Source Type: research

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