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Condition: Heatstroke

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Total 1318 results found since Jan 2013.

Treating exertional heat stroke: Limited understanding of the female response to cold water immersion
According to an expansive body of research and best practice statements, whole-body cold water immersion is the gold standard treatment for exertional heat stroke. However, as this founding evidence was predominantly drawn from males, the current guidelines for treatment are being applied to women without validation. Given the recognised differences in thermal responses experienced by men and women, all-encompassing exertional heat stroke treatment advice may not effectively protect both sexes. In fact, recent evidence suggests that hyperthermic women cool faster than hyperthermic men during cold water immersion. This rais...
Source: Frontiers in Physiology - November 25, 2022 Category: Physiology Source Type: research

Immersive Cooling in the Prehospital Setting for Heat Stroke: A Case Report
Prehosp Emerg Care. 2023 Apr 11:1-5. doi: 10.1080/10903127.2023.2201515. Online ahead of print.ABSTRACTNon-exertional heat stroke is defined as exposure to high outdoor temperatures, core body temperature >40 °C, and alteration of mentation. Early identification and treatment are imperative to reduce morbidity and mortality in these patients. Cold water immersion therapy is the most efficient and efficacious modality in treating heat stroke, yet it is rarely initiated in the prehospital setting. We outline a case of an 82-year-old man found unconscious outside during a regional heat wave with a temperature >107F. He...
Source: Prehospital Emergency Care - April 11, 2023 Category: Endocrinology Authors: Douglas Young Bryan Everitt Brandon Fine David Miramontes Source Type: research

Association between cooling temperature and outcomes of patients with heat stroke
This study explored the relationship between body temperature and adverse outcomes in patients with heat stroke to identify the optimal target body temperature within the first 24  h. This retrospective, multicentre study enrolled 143 patients admitted to the emergency department and diagnosed with heat stroke. The primary outcome was the in-hospital mortality rate, while secondary outcomes included the presence and number of damaged organs and neurological sequelae at disch arge. A body temperature curve was built using a generalized additive mixed model, and the association between body temperatures and outcomes was est...
Source: Internal and Emergency Medicine - May 3, 2023 Category: Emergency Medicine Source Type: research

Xuebijing injection alleviates liver injury by inhibiting secretory function of Kupffer cells in heat stroke rats.
CONCLUSION: XBJ can alleviate HS-induced systemic inflammatory response syndrome and liver injury in rats, and improve outcomes. These protective effects may be due to the ability of XBJ to inhibit cytokine secretion by KCs. PMID: 23789225 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - April 1, 2013 Category: Complementary Medicine Authors: Chen Y, Tong H, Zhang X, Tang L, Pan Z, Liu Z, Duan P, Su L Tags: J Tradit Chin Med Source Type: research

Research By The Montana Center For Work Physiology And Exercise Metabolism Proves Heat Stroke Death Can Occur Even When Properly Hydrated
Prevention starts with recognizing one's own limits Each year, more than 1,000 people die from heat stroke in the United States. Long thought to be the product of dehydration, traditional prevention and treatment of heat related illness has been to drink more water. More recent research by the University of Montana's Center for Work Physiology and Exercise Metabolism (Montana WPEM) has proven that, while proper hydration is important, the key step to preventing heat stroke is to recognize when one is working too hard for the given environment and slowing down or stopping...
Source: Health News from Medical News Today - June 28, 2013 Category: Consumer Health News Tags: Public Health Source Type: news

Heat-stroke in an epileptic patient treated by topiramate: Follow-up by magnetic resonance imaging including diffusion-weighted imaging with apparent diffusion coefficient measure
Heat stroke is the most severe form of heat-related illnesses, i.e. a life-threatening condition characterized by profound central nervous system abnormalities (including delirium, seizures, or coma) associated with severe hyperthermia (a core temperature typically but not always>40°C). Recently, clinical and experimental evidence suggested a complex interplay between heat cytotoxicity, coagulation, and cytokine-mediated systemic inflammatory response syndrome which finally may result in multi-organ system failure which is the ultimate cause of mortality . Exposure to high environmental temperatures is classified as passi...
Source: Clinical Neurology and Neurosurgery - February 13, 2013 Category: Neurosurgery Authors: Carmine Franco Muccio, Elvio De Blasio, Maria Venditto, Gennaro Esposito, Rossana Tassi, Alfonso Cerase Tags: Case reports Source Type: research

Selective anterograde amnesia associated with hippocampal and splenial damage after heat stroke
Heat stroke (HS) occurs after exposure to high environmental temperatures, causing thermoregulatory failure characterized by a core body temperature above 40°C, loss of sweating, tachycardia, hypotension, altered mentality and confusion . There are two forms of HS, classic or nonexertional HS resulted from exposure to high environmental temperatures and exertional HS from strenuous physical exercise . Generalized circulatory collapse and multiorgan dysfunction involving the central nervous system (CNS) can also be associated with HS unless treated at an early stage. The cerebellum is the most frequently affected area of t...
Source: Clinical Neurology and Neurosurgery - April 22, 2013 Category: Neurosurgery Authors: Seong-Yi Cha, Tae-Ho Kang, Seong-Jang Kim, Hyo-Young Lee, Hak-Jin Kim, Dae-Soo Jung, Eun-Joo Kim Tags: Case reports Source Type: research

Exertional heat stroke, rhabdomyolysis and susceptibility to malignant hyperthermia
We report a case of exertional heat stroke and rhabdomyolysis in a man later determined to have the malignant hyperthermia phenotype. We review the existing literature regarding this association and suggest future research that could address areas of remaining clinical uncertainty.
Source: Internal Medicine Journal - September 4, 2013 Category: Internal Medicine Authors: J. Thomas, T. Crowhurst Tags: Brief Communication Source Type: research

Increased cytokine and chemokine gene expression in the CNS of mice during heat stroke recovery.
Abstract Heat stroke (HS) is characterized by a systemic inflammatory response syndrome (SIRS) consisting of profound core temperature (Tc) changes in mice. Encephalopathy is common at HS collapse, but inflammatory changes occurring in the brain during the SIRS remain unidentified. We determined the association between inflammatory gene expression changes in the brain with Tc disturbances during HS recovery in mice. Gene expression changes of heat shock protein (HSP)72, heme-oxygenase (hmox1), cytokines (IL-1β, IL-6, TNFα), cyclooxygenase enzymes (COX-1, COX-2), chemokines (MCP-1, MIP-1α, MIP-1β, CX3CR1), and ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 11, 2013 Category: Physiology Authors: Biedenkapp JC, Leon LR Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research