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Epidemiology of cardiovascular disease in Japan: An overview study
J Cardiol. 2023 Aug 15:S0914-5087(23)00200-9. doi: 10.1016/j.jjcc.2023.08.006. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs), such as heart disease and stroke, have a significant impact on life expectancy, healthy life expectancy, and medical costs in Japan. Each prefecture is currently promoting measures in accordance with the Japanese National Plan for Promotion of Measures Against Cerebrovascular and Cardiovascular Disease, which was established by the government. In recent years, the crude mortality rate of heart disease in Japan has been increasing year by year with the aging population. Meanwhile, the ...
Source: Journal of Cardiology - August 17, 2023 Category: Cardiology Authors: Tetsuya Ohira Eri Eguchi Fumikazu Hayashi Minako Kinuta Hironori Imano Source Type: research

Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials
CONCLUSION: Despite challenges, observational methods and real-world data can be leveraged in certain important situations for a more timely evaluation of drug effectiveness and safety in more diverse and representative patient populations.PMID:37589143 | DOI:10.1177/17407745231193137
Source: Clinical Trials - August 17, 2023 Category: Research Authors: Joshua D Wallach Yihong Deng Eric C Polley Sanket S Dhruva Jeph Herrin Kenneth Quinto Charu Gandotra William Crown Peter Noseworthy Xiaoxi Yao Molly Moore Jeffery Timothy D Lyon Joseph S Ross Rozalina G McCoy Source Type: research

Epidemiology of cardiovascular disease in Japan: An overview study
J Cardiol. 2023 Aug 15:S0914-5087(23)00200-9. doi: 10.1016/j.jjcc.2023.08.006. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs), such as heart disease and stroke, have a significant impact on life expectancy, healthy life expectancy, and medical costs in Japan. Each prefecture is currently promoting measures in accordance with the Japanese National Plan for Promotion of Measures Against Cerebrovascular and Cardiovascular Disease, which was established by the government. In recent years, the crude mortality rate of heart disease in Japan has been increasing year by year with the aging population. Meanwhile, the ...
Source: Journal of Cardiology - August 17, 2023 Category: Cardiology Authors: Tetsuya Ohira Eri Eguchi Fumikazu Hayashi Minako Kinuta Hironori Imano Source Type: research

Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials
CONCLUSION: Despite challenges, observational methods and real-world data can be leveraged in certain important situations for a more timely evaluation of drug effectiveness and safety in more diverse and representative patient populations.PMID:37589143 | DOI:10.1177/17407745231193137
Source: Clinical Trials - August 17, 2023 Category: Research Authors: Joshua D Wallach Yihong Deng Eric C Polley Sanket S Dhruva Jeph Herrin Kenneth Quinto Charu Gandotra William Crown Peter Noseworthy Xiaoxi Yao Molly Moore Jeffery Timothy D Lyon Joseph S Ross Rozalina G McCoy Source Type: research

Identification of immune-related biomarkers co-occurring in acute ischemic stroke and acute myocardial infarction
ConclusionUsing comprehensive bioinformatics analyses, we identified five immune-related biomarkers that significantly contributed to the pathophysiological mechanisms of both AIS and AMI. These biomarkers can be used to monitor and prevent AIS after AMI, or vice versa.
Source: Frontiers in Neurology - August 17, 2023 Category: Neurology Source Type: research

Associations of MAFLD and MAFLD subtypes with the risk of the incident myocardial infarction and stroke
In conclusion, a diagnosis of MAFLD is associated with an increased risk of MI or stroke, and the assessment of MAFLD and its subtypes should be a component of the cardiovascular risk assessment.PMID:37586479 | DOI:10.1016/j.diabet.2023.101468
Source: Diabetes and Metabolism - August 16, 2023 Category: Endocrinology Authors: Shen Chen Hongliang Xue Rong Huang Ke Chen Haoyang Zhang Xu Chen Source Type: research