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Safety outcomes of ticagrelor among patients with STE-ACS post streptokinase therapy-a retrospective observational study
Conclusion: In real practice, ticagrelor swi tching among patients with STE-ACS post streptokinase therapy did not differ regarding safety outcomes and composite of efficacy outcomes compared with clopidogrel.
Source: PLoS One - August 4, 2023 Category: Biomedical Science Authors: Phornpaka Ueapornpanith Source Type: research

Safe and effective thrombolysis in free flap salvage: Intra-arterial urokinase infusion
by Jun Hyeok Kim, Sungyeon Yoon, Heeyeon Kwon, Deuk Young Oh, Young-Joon Jun, Suk-Ho Moon Despite the high success rate in reconstruction using free tissue transfer, flap failure is often caused by microvascular thrombosis. In a small percentage of cases with complete flap loss, a salvage procedure is performed. In the present study, the effectiveness of intra-arterial urokinase infusi on through the free flap tissue was investigated to develop a protocol to prevent thrombotic failure. The retrospective study evaluated the medical records of patients who underwent salvage procedure with intra-arterial urokinase infusion a...
Source: PLoS One - March 13, 2023 Category: Biomedical Science Authors: Jun Hyeok Kim Source Type: research

Causes of death of patients with non-valvular atrial fibrillation in Asians
ConclusionDeath due to ischemic stroke was responsible for only 4.7% of all deaths in Asian AF patients. Non-CV death, such as infection/sepsis or malignancy, was more far more prevalent than CV death in Asian AF patients. An improved integrated care approach is needed to reduce the prevalence of non-CV death in Asian AF patients.
Source: PLoS One - March 1, 2023 Category: Biomedical Science Authors: Rungroj Krittayaphong Source Type: research

Prognostic impact of catheter ablation in patients with asymptomatic atrial fibrillation
ConclusionsIn the post-hoc analysis of the matched AF cohort, catheter ablation as compared with conservative management was associated with better long-term clinical outcomes among asymptomatic AF patients only when the previous AF-related complications were present.
Source: PLoS One - December 15, 2022 Category: Biomedical Science Authors: Tetsuma Kawaji Source Type: research

Venous thromboembolism: Why is it still a significant health problem?
CONCLUSIONS: Understanding the interaction between environmental and genetic factors appears to be crucial in the diagnostic process. It can provide insight into the pathophysiology of VTE, potentially identifying options for targeted prevention and treatment. However, due to differences in clinical presentation, diagnosing pulmonary embolism may not be an easy task which perfectly illustrates the scale and complexity of the disease.PMID:36368288 | DOI:10.1016/j.advms.2022.10.002
Source: Advances in Medical Sciences - November 11, 2022 Category: Biomedical Science Authors: Monika Oleksiuk-B ójko Anna Lisowska Source Type: research

Determinants for a low dose of alteplase and its relationship to a lower intracerebral bleeding risk in acute ischemic stroke
Conclusions: Patients with increasing age, a higher baseline systolic blood pressure, and previous ischemic stroke were at a higher odd of receiving a low-dose of alteplase. The low-dose was associated with a lower risk of developing symptomatic intracranial hemorrhage.PMID:36313231 | PMC:PMC9608043 | DOI:10.7150/ijms.76105
Source: International Journal of Medical Sciences - October 31, 2022 Category: Biomedical Science Authors: Jie Chen Hangfeng Li Hanhan Lei Shuangfang Fang Qilin Yuan Yangui Chen Dongping Chen Ronghua Chen Yixian Zhang Jin Wei Guangliang Chen Zhiting Chen Nan Liu Hou-Wei Du Source Type: research

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