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Condition: Bleeding
Education: Academia

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Total 422 results found since Jan 2013.

Association Between Atrial High-Rate Episodes and Ischemic/Major Bleeding Events in Patients With a Cardiac Implantable Electronic Device  - A 10-Year, Single-Center Historical Cohort Study
CONCLUSIONS: Longer AHRE duration is associated with a high number of major bleeding and ischemic events. Monitoring these bleeding risks is mandatory when clinicians are considering anticoagulation therapy for such patients.PMID:33867407 | DOI:10.1253/circj.CJ-20-1269
Source: Circulation Journal - April 19, 2021 Category: Cardiology Authors: Hironori Ishiguchi Akihiko Shimizu Masahiro Ishikura Masaaki Yoshida Koji Imoto Kazuhiko Sonoyama Tetsuya Kawabata Takashi Sugamori Masaya Ogawa Tomoyuki Uchida Tsukasa Nakamura Takeshi Morimoto Yu Yasuda Kazuaki Tanabe Yasuhiro Yoshiga Takayuki Okamura S Source Type: research

Effects of Acute Coronary Syndrome and Stable Coronary Artery Disease on Bleeding and Ischemic Risk After Percutaneous Coronary Intervention
CONCLUSIONS: Bleeding risk after PCI depended on both ACS presentation and HBR, with a significant effect of ACS within 30 days.PMID:33907052 | DOI:10.1253/circj.CJ-21-0016
Source: Circulation Journal - April 28, 2021 Category: Cardiology Authors: Masahiro Natsuaki Takeshi Morimoto Hiroki Shiomi Kazushige Kadota Tomohisa Tada Yasuaki Takeji Yukiko Matsumura-Nakano Yusuke Yoshikawa Hirotoshi Watanabe Ko Yamamoto Kazuaki Imada Takenori Domei Kyohei Yamaji Kazuhisa Kaneda Ryoji Taniguchi Natsuhiko Eha Source Type: research

Evaluation of Prescribing Practices and Outcomes Using Direct-Acting Oral Anticoagulants After Cardiac Surgery
Clin Ther. 2021 May 30:S0149-2918(21)00203-4. doi: 10.1016/j.clinthera.2021.04.009. Online ahead of print.ABSTRACTPURPOSE: Cardiac surgery patients frequently require anticoagulation. Warfarin remains the preferred agent, and a few trials have reported negative outcomes with the use of direct-acting oral anticoagulants (DOACs) in these patients. Therefore, limited literature exists that supports the dosing, safety, and efficacy of DOACs within the cardiac surgery population.METHODS: This single-center, retrospective analysis was conducted at a tertiary academic medical center. All data were extrapolated from electronic med...
Source: Clinical Therapeutics - June 3, 2021 Category: Drugs & Pharmacology Authors: Dareen M Kanaan Bryan M Cook Julie Kelly Rhynn Malloy Source Type: research

Outcomes of Vascular Closure Device Use After Transfemoral Coronary Intervention: Insights From the EXCEL Trial
CONCLUSION: In the EXCEL trial, LM-CAD PCI via TFA using VCD was associated with similar 30-day rates of bleeding and comparable early and late major adverse cardiovascular events compared with manual compression.PMID:34170842
Source: The Journal of Invasive Cardiology - June 25, 2021 Category: Cardiology Authors: Toshiki Kuno Bimmer E Claessen Paul Guedeney Patrick W Serruys Joseph F Sabik Charles A Simonton David E Kandzari Marie-Claude Morice Zixuan Zhang Ovidiu Dressler Roxana Mehran Ori Ben-Yehuda Arie Pieter Kappetein Gregg W Stone Source Type: research

Incidence and Risk Factors for Antiplatelet Therapy –Related Bleeding Complications Among Elderly Patients After Coronary Stenting: A Multicenter Retrospective Observation
Conclusion: A higher PRECISE-DAPT score of 33 might be a more reasonable cutoff value for predicting BARC ≥2 type bleeding risk in CAD patients (≥75 years). In addition, the history of hemorrhagic stroke, peptic ulcer, and myocardial infarction were identified as the risk factors of BARC ≥2 type bleeding events.
Source: Frontiers in Pharmacology - July 30, 2021 Category: Drugs & Pharmacology Source Type: research

Abbreviated Antiplatelet Therapy in Patients at High Bleeding Risk With or Without Oral Anticoagulant Therapy After Coronary Stenting: An Open-Label, Randomized, Controlled Trial
Conclusions: Rates of NACE and MACCE did not differ with abbreviated APT in high bleeding risk patients with or without an OAC indication and resulted in lower bleeding rates in patients without an OAC indication. Clinical Trial Registration: URL: https://www.clinicaltrials.gov Unique identifier:NCT03023020.PMID:34455849 | DOI:10.1161/CIRCULATIONAHA.121.056680
Source: Circulation - August 30, 2021 Category: Cardiology Authors: Pieter C Smits Enrico Frigoli Jan Tijssen Peter J üni Pascal Vranckx Yukio Ozaki Marie-Claude Morice Bernard Chevalier Yoshinobu Onuma Stephan Windecker Pim A L Tonino Marco Roffi Maciej Lesiak Felix Mahfoud Jozef Bartunek David Hildick-Smith Antonio Col Source Type: research