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Specialty: Cardiology
Condition: Asthma
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Total 29 results found since Jan 2013.
Noncardiac comorbidities and intensive up ‐titration of oral treatment in patients recently hospitalized for heart failure: insights from the STRONG‐HF trial
ConclusionsIn the STRONG-HF trial, non-cardiac comorbidities neither limited the rapid up-titration of HF-therapies, nor attenuated the benefit of HIC on primary endpoint.In the context of a clinical trial, the benefit-risk ratio favors the rapid up-titration of HF-therapies even in patients with multiple NCCsThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - September 21, 2023 Category: Cardiology Authors: Ovidiu Chioncel,
Beth Davison,
Marianna Adamo,
Laura E Antohi,
Mattia Arrigo,
Marianela Barros,
Jan Biegus,
Kamil ė Čerlinskaitė‐Bajorė,
Jelena Celutkiene,
Alain Cohen‐Solal,
Albertino Damasceno,
Rafael Diaz,
Christopher Edwards,
Gera Tags: Research Article Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
Impact of age on characteristics, performance measures and outcomes of inpatients for heart failure in Beijing, China
ConclusionsHF patients aged ≥75 years had distinct clinical profiles, received worse in-hospital therapies and experienced higher in-hospital and 1 year mortality.
Source: ESC Heart Failure - August 2, 2023 Category: Cardiology Authors: Cong Yuan,
Liu He,
Xin Du,
Chao Jiang,
Shi ‐Jun Xia,
Xin Zhao,
Song‐Nan Li,
Cai‐Hua Sang,
De‐Yong Long,
Jian‐Zeng Dong,
Chang‐Sheng Ma Tags: Original Article Source Type: research
ICAM-1 and VCAM-1: gatekeepers in various inflammatory and cardiovascular disorders
Clin Chim Acta. 2023 Jul 11:117487. doi: 10.1016/j.cca.2023.117487. Online ahead of print.ABSTRACTLeukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular space are caused by cellular stimulation and local expression of adhesion molecules. Intercellular adhesion molecule 1 (ICAM-1) and Vascular cell adhesion molecule 1 (VCAM-1) belong to the immunoglobulin superfamily of cell adhesion molecules with a crucial role in mediating t...
Source: Atherosclerosis - July 13, 2023 Category: Cardiology Authors: Varinder Singh Rupinder Kaur Pratima Kumari Chirag Pasricha Ravinder Singh Source Type: research
Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization study
Respir Investig. 2023 Jan 20;61(2):149-152. doi: 10.1016/j.resinv.2022.12.004. Online ahead of print.ABSTRACTInterleukin-5 (IL-5) inhibitors have revolutionized the management of eosinophilic asthma. However, IL-5 is thought to play a protective role in atherosclerosis, and cardiovascular safety data for IL-5i are scarce. We used population-level data to examine the association between genetically proxied IL-5i and the risk of cardiovascular diseases. Genetic instruments for IL-5i were selected from a genome-wide association study of eosinophil count in 563,946 individuals. Genetic association data for coronary artery dise...
Source: Atherosclerosis - January 22, 2023 Category: Cardiology Authors: Philip Alton David M Hughes Sizheng Steven Zhao Source Type: research
Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study
CONCLUSIONS AND RELEVANCE: Our results suggest that joint inhibition of CETP and PCSK9 has additive effects on lipid traits and disease risk, including a lower risk of CAD. Further research may explore whether a combination of CETP- and PCSK9-related therapeutics can benefit high-risk patients who are unable to reach treatment targets with existing options.PMID:35921096 | DOI:10.1001/jamacardio.2022.2333
Source: Atherosclerosis - August 3, 2022 Category: Cardiology Authors: Arjen J Cupido Laurens F Reeskamp Aroon D Hingorani Chris Finan Folkert W Asselbergs G Kees Hovingh Amand F Schmidt Source Type: research
Allergies and the Heart; Tai Chi After Stroke; Viagra for Congenital Heart Disease?
(MedPage Today) -- Study finds that people with allergies and asthma were more likely to have high blood pressure and coronary heart disease, the American College of Cardiology announced.
The American Heart Association reviews the cardiovascular...
Source: MedPage Today Cardiovascular - April 12, 2022 Category: Cardiology Source Type: news
Oral tolerance: an updated review
Immunol Lett. 2022 Apr 5:S0165-2478(22)00041-4. doi: 10.1016/j.imlet.2022.03.007. Online ahead of print.ABSTRACTOral tolerance (OT) has classically been defined as the specific suppression of cellular and/or humoral immune responses to an antigen by prior administration of the antigen through the oral route. Multiple mechanisms have been proposed to explain the induction of OT including T cell clonal depletion and anergy when high doses of antigens are fed, and regulatory T (Treg) cell generation following oral administration of low and repeated doses of antigens. Oral antigen administration suppresses the immune response ...
Source: Atherosclerosis - April 8, 2022 Category: Cardiology Authors: Rafael M Rezende Howard L Weiner Source Type: research
Leukotriene receptor antagonists role in recuding the cardiovascular and cerebrovascular risk: A case-control study in southern Spain
Background and Aims: Leukotriene receptor antagonists (LTRAs) are used in asthmatic patients, however different studies indicate that LTRAs can decrease intimal hyperplasia after vascular injury, and have a protective role in cerebral ischemia. The aim of our study was to assess the role of LTRAs in reducing myocardial infarction (MI) and ischemic stroke (IS) risk in patients from two Primary Health Care Centers of Granada.
Source: Atherosclerosis - December 1, 2020 Category: Cardiology Authors: M. Hoxha, V. Malaj, C. Rivilla Doce, A.B. Cavanillas Source Type: research
Hypertension and comorbidities in rural and urban Chinese older people: an epidemiological sub-analysis from the SAGE study.
CONCLUSIONS: Our study implies that health promotion policies targeting older people should be developed. Rural areas should be a priority, and investment in the quality of healthcare in rural areas is urgently needed.
PMID: 32886761 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - September 3, 2020 Category: Cardiology Authors: Li H, Hu YJ, Lin H, Xia H, Guo Y, Wu F Tags: Am J Hypertens Source Type: research
Prognostic role of bronchial asthma in patients with heart failure
AbstractThere are few reports investigating the relationship between bronchial asthma (BA) and heart failure (HF). We hypothesized BA may have impact on prognosis in patients with HF. Among 323 consecutive outpatients with HF, 191 patients without chronic obstructive pulmonary disease were analyzed. Twenty patients had BA, most of whom (80.0%) had preserved left ventricular ejection fraction (LVEF ≥ 50%). The use of β-blockers was less frequent (55.0% vs 83.0%.p = 0.01), systolic blood pressure (133 ± 22 vs 120 ± 17 mmHg,p = 0.003), and heart rate (83 ± 14 vs 74 ± 15 bpm,p = 0.02) ...
Source: Heart and Vessels - January 21, 2020 Category: Cardiology Source Type: research
Pre ‐hospital management protocols and perceived difficulty in diagnosing acute heart failure
ConclusionsThe prevalence of AHF protocols is rather high but the contents seem to vary. Difficulty of diagnosing suspected AHF seems to be moderate compared with other pre ‐hospital conditions.
Source: ESC Heart Failure - November 7, 2019 Category: Cardiology Authors: Pia Harjola, Òscar Miró,
Francisco J. Martín‐Sánchez,
Xavier Escalada,
Yonathan Freund,
Andrea Penaloza,
Michael Christ,
David C. Cone,
Said Laribi,
Markku Kuisma,
Tuukka Tarvasmäki,
Veli‐Pekka Harjola,
on behalf of the EMS‐AHF Study Tags: Original Research Article Source Type: research
Associations between statins and coronary artery disease and stroke risks in patients with asthma –chronic obstructive pulmonary disease overlap syndrome: A time-dependent regression study
To determine the effects of statin use on coronary artery disease (CAD) and stroke risks in patients with asthma –chronic obstructive pulmonary disease overlap syndrome (ACOS).
Source: Atherosclerosis - February 11, 2019 Category: Cardiology Authors: Jun-Jun Yeh, Cheng-Li Lin, Chung Y. Hsu, Zonyin Shae, Chia-Hung Kao Source Type: research
