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The association between obstructive sleep apnea and stroke in sickle-cell disease children
ConclusionPatients who had OSA had a higher prevalence of stroke compared to non-OSA patients by 16% with almost three times higher odds. The difference was statistically significant in bivariant but not multivariant analysis. The rate of hospitalization, emergency visit, and blood transfusion were not affected by OSA status. Screening for OSA in high-risk patients such as SCD children and early management could prevent the risk of SCD complications.
Source: European Archives of Oto-Rhino-Laryngology - January 29, 2022 Category: ENT & OMF Source Type: research

Soluble P-selectin levels in patients with obstructive sleep apnea: a systematic review and meta-analysis
ConclusionThe pooled results reveal that OSA patients have higher sP-selectin levels than non-OSA controls. This conclusion remains unaltered in all subgroups other than the subgroup of mild OSA patients. Additional studies are warranted to better identify the role of sP-selectin as a potential biomarker in OSA patients.
Source: European Archives of Oto-Rhino-Laryngology - May 5, 2021 Category: ENT & OMF Source Type: research

Functional Rhinoplasty and Uvuloplasty for Sleep-Disordered Breathing: A Step-by-Step Guide
Sleep-disordered breathing (SDB) represents a wide range of sleep-related breathing abnormalities including snoring, upper airway resistance syndrome, respiratory event –related arousal, obstructive sleep apnea (OSA), and obstructive sleep apnea syndrome.1 It has been established in the literature that SDB is associated with hypertension, stroke, hyperlipidemia, cardiac dysrhythmias, and excessive daytime sleepiness (EDS).1,2 The therapeutic resolution of these m edical maladies has proven nonlinear and less than optimal by most treatment approaches for OSA.
Source: Journal of Oral and Maxillofacial Surgery - March 30, 2021 Category: ENT & OMF Authors: Omar AbdelBaky, John Brothers, Richard Finn Tags: Resident corner Source Type: research

Association of Obstructive Sleep Apnea With the Risk of Repeat Adverse Cardiovascular Events in Patients With Newly Diagnosed Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.
CONCLUSION: Patients with preexisting OSA are at greater risk of subsequent cardiovascular events after onset of ACS. Further studies should investigate the treatment of OSA in patient with ACS. PMID: 33570429 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - February 11, 2021 Category: ENT & OMF Authors: Yang SH, Xing YS, Wang ZX, Liu YB, Chen HW, Ren YF, Chen JL, Li SB, Wang ZF Tags: Ear Nose Throat J Source Type: research

Discussion Related to “Maxillomandibular Advancement for Obstructive Sleep Apnea Is Associated with Very Long-Term Overall Sleep-Related Quality-of-Life Improvement.”
Obstructive sleep apnea (OSA) is a common chronic disease resulting from repetitive collapse of the airway during sleep, causing hypoxemia and sleep fragmentation. Untreated OSA at varying severity levels has been linked to hypertension, cardiac arrhythmias, stroke, diabetes, decreased work performance, decreased quality of life (QOL), and increased all-cause mortality. It is a costly global health concern as the increasing prevalence of OSA parallels the rising rates of obesity. OSA affects approximately 22% of men and 17% of women, while severe OSA is present in 2-4% of the adult population1.
Source: Journal of Oral and Maxillofacial Surgery - January 28, 2020 Category: ENT & OMF Authors: Jennifer M. Dolan, Ashleigh M. Weyh, Juliana Gomez, Salam O. Salman Source Type: research

Commentary - “Maxillomandibular Advancement for Obstructive Sleep Apnea Is Associated with Very Long-Term Overall Sleep-Related Quality-of-Life Improvement”
Obstructive sleep apnea (OSA) is a common chronic disease resulting from repetitive collapse of the airway during sleep, causing hypoxemia and sleep fragmentation. Untreated OSA at varying severity levels has been linked to hypertension, cardiac arrhythmias, stroke, diabetes mellitus, decreased work performance, decreased quality of life, and increased all-cause mortality. OSA is a costly global health concern because the increasing prevalence of OSA has paralleled the increasing rates of obesity.
Source: Journal of Oral and Maxillofacial Surgery - January 28, 2020 Category: ENT & OMF Authors: Jennifer M. Dolan, Ashleigh M. Weyh, Juliana Gomez, Salam O. Salman Tags: Resident corner Source Type: research

Severe Obstructive Sleep Apnea with Imaged Carotid Plaque Significantly Associated with Systemic Inflammation
Persons with obstructive sleep apnea (OSA) are at heightened risk of myocardial infarction (MI) and stroke caused by adiposity and intermittent hypoxia which provoke proinflammatory cytokines to induce systemic/vascular inflammation resulting in endothelial dysfunction and development of atherosclerotic plaque. We aim to compare the levels of systemic inflammation between groups of patients having severe OSA with and without carotid artery calcified plaque (CACP+/CACP –) on their panoramic image (PI) as indexed by the neutrophil-lymphocyte ratio (NLR).
Source: Journal of Oral and Maxillofacial Surgery - February 12, 2019 Category: ENT & OMF Authors: Urie K. Lee, Stanley Yung Liu, Michelle R. Zeidler, Hoang-Anh Tran, Tina I. Chang, Arthur H. Friedlander Source Type: research

Severe Obstructive Sleep Apnea With Imaged Carotid Plaque Is Significantly Associated With Systemic Inflammation
This study compared levels of systemic inflammation between groups of patients with severe OSA with and without carotid artery calcified plaque (CACP+ and CACP −, respectively) on their panoramic image (PI) as indexed by the neutrophil-to-lymphocyte ratio (NLR).
Source: Journal of Oral and Maxillofacial Surgery - February 11, 2019 Category: ENT & OMF Authors: Urie K. Lee, Stanley Yung Liu, Michelle R. Zeidler, Hoang-Anh Tran, Tina I. Chang, Arthur H. Friedlander Tags: Pathology Source Type: research

Severity of Obstructive Sleep Apnea is Positively Associated with the Presence of Carotid Artery Atheromas
Hypoxemia and hypertension caused by obstructive sleep apnea (OSA) often results in atherosclerosis of the carotid and coronary vessels, and heightened risk of stroke and myocardial infarction (MI). Therefore, we sought to determine if severity of OSA, based on the apnea-hypopnea index (AHI), is associated with the presence of calcified carotid artery (atherosclerotic) plaque (CCAP) seen on panoramic images (PIs).
Source: Journal of Oral and Maxillofacial Surgery - August 20, 2018 Category: ENT & OMF Authors: Tina I. Chang, Urie K. Lee, Michelle R. Zeidler, Stanley Yung Liu, John C. Polanco, Arthur H. Friedlander Source Type: research

Hypercoagulability, Obstructive Sleep Apnea, and Pulmonary Embolism
To the Editor We read with great interest the article written by Hong et al. They found that prothrombin time in patients with obstructive sleep apnea (OSA) was shorter compared with controls, concluding that OSA might lead to a prothrombotic state, a probable contributing factor to the increase in cardiovascular complications in OSA, including ischemic heart disease and stroke. Observational studies suggest that suppression of apneas by continuous positive airway pressure (CPAP) may improve cardiovascular outcomes. Nevertheless, recent data from a large randomized clinical trial did not prevent cardiovascular events in pa...
Source: JAMA Otolaryngology - Head and Neck Surgery - March 22, 2018 Category: ENT & OMF Source Type: research

Sleep apnea and risk of vertigo: A nationwide population ‐based cohort study
ConclusionThis is the first nationwide population‐based cohort study to investigate the association between sleep apnea and vertigo. The findings strongly support that sleep apnea is an independent risk factor for vertigo. Based on the study results, physicians should be aware of potential vertigo occurrence following sleep apnea. Level of Evidence4. Laryngoscope, 2017
Source: The Laryngoscope - August 3, 2017 Category: ENT & OMF Authors: Ming ‐Shao Tsai, Li‐Ang Lee, Yao‐Te Tsai, Yao‐Hsu Yang, Chia‐Yen Liu, Meng‐Hung Lin, Cheng‐Ming Hsu, Chin‐Kuo Chen, Hsueh‐Yu Li Tags: Laryngology Source Type: research

Pressure monitoring of the Mueller maneuver. Our experience in twenty ‐five Obstructive Sleep Apnea Hypopnoea Syndrome patients with oropharyngeal obstruction
This article is protected by copyright. All rights reserved.
Source: Clinical Otolaryngology - July 31, 2016 Category: ENT & OMF Authors: Jacopo Cambi, Paola Staffa, Maria Carla Spinosi Tags: Our Experience Source Type: research