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Primary Aldosteronism
Am Fam Physician. 2023 Sep;108(3):273-277.ABSTRACTPrimary aldosteronism is the underlying cause of hypertension in primary care settings in approximately 6% of cases, and it is even more common in patients with resistant hypertension. However, it is estimated that only about 2% of patients who have risk factors for primary aldosteronism have been formally tested or diagnosed. The first step in the diagnosis of primary aldosteronism is case detection and involves testing patients who are at risk, including individuals with resistant hypertension, as well as those with well-controlled hypertension and a first-degree relative...
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Keith B Quencer J B Rugge Olga Senashova Source Type: research

Relationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke
Conclusion: Our findings indicate a relationship between coronary atherosclerotic burden measured by the CAC score and the severity of sleep apnea. Performing polysomnography could be useful for investigating the severity of hidden coronary artery disease among these patients.
Source: Frontiers in Neurology - July 30, 2019 Category: Neurology Source Type: research

Stroke Volume Predicts Nocturnal Hypoxemia in the Acute Ischemic Stroke after Intravenous Thrombolysis
The Goal: The aim of the study was to investigate whether stroke volume or the presence of ischemic stroke lesion on follow-up computed tomography 1 day after admission had association with sleep apnea among ischemic stroke patients undergoing thrombolysis. Materials and Methods: We prospectively recruited 110 consecutive ischemic stroke patients and performed computed tomography on admission and after 24 hours after intravenous thrombolysis. Stroke volume was measured from post-thrombolysis computed tomography scans.
Source: Journal of Stroke and Cerebrovascular Diseases - July 1, 2019 Category: Neurology Authors: Jaana K. Huhtakangas, Tarja Saaresranta, Michaela K. Bode, Risto Bloigu, Juha Huhtakangas Source Type: research

Poor Sleep Linked To Dangerous Plaque Buildup In Arteries
By Sandee LaMotte, CNN (CNN) — Here’s another reason why getting a good night’s sleep should be on your must-do list: Sleeping fewer than six hours a night or waking frequently raises your risk of developing damaging plaque in arteries throughout your body, not just your heart. Previous research has shown poor sleep to be strongly associated with coronary heart disease, but “This is the first study to show that objectively measured sleep is independently associated with atherosclerosis throughout the body,” José Ordovás, director of nutrition and genomics at the Jean Mayer USDA Human Nutriti...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Heart Disease Sleep Tufts University Source Type: news

Relationship between sleep disordered breathing and coronary artery calcium in ischemic stroke patients
Introduction: Obstructive Sleep Apnea (OSA) is associated with increased risk of stroke and cardiovascular mortality. In ischemic patients, the major cause of death during follow-up is coronary artery disease. Coronary calcium score (CAC) is a score measured from quantification of calcified plaques with chest computed tomography. CAC has been shown to be associated with future risk of myocardial infarction and cardiovascular mortality. Several studies showed the positive correlation between sleep apnea and CAC in normal population, which may be contributed by progressive worsening of atherosclerosis.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: Y.H. Choi, S.H. Yim, K.H. Cho, Y.-J. Cho, K. Heo, Y.D. Kim Tags: Sleep Breathing Disorders Source Type: research

Computational tools could change the way sleep apnea is treated
Imagine that before performing surgery, doctors could consult software that would determine the actual effectiveness of the procedure before even lifting a scalpel. With the use of a computational model of the human airway being developed by Jeff Eldredge, a professor at the Henry Samueli School of Engineering and Applied Sciences at UCLA, people who suffer from sleep apnea may one day benefit from such a scenario. Previously, Eldredge, a professor of mechanical and aerospace engineering, had been working on creating models that simulated the interactions between blood and vessel walls with Shao-Ching Huang, an expert in h...
Source: UCLA Newsroom: Health Sciences - February 10, 2016 Category: Universities & Medical Training Source Type: news