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Prevalence of Activity Limitations and Association with Multimorbidity Among US Adults 50 to 64  Years Old
ConclusionsProblems with function are not limited to older adults and multimorbidity may be helpful for identifying middle-aged adults with a high prevalence of activity limitations.
Source: Journal of General Internal Medicine - August 20, 2019 Category: Internal Medicine Source Type: research

New Biomarkers for Atherothrombosis in Antiphospholipid Syndrome: Genomics and Epigenetics Approaches
Conclusions In recent years, there have been many advances in the understanding of the molecular basis for vascular involvement in APS, but many areas need to be further investigated, in particular the association between altered genetic/epigenetic profiles, autoantibodies and clinical manifestations, and the effectiveness of new therapeutic strategies. It would be interesting to apply next generation sequencing technologies like RNA-Seq along with GWAS to screen both, the gene profile and the whole transcriptome of large cohorts of primary APS patients, in order to reveal the mutations/polymorphisms, post-transcriptiona...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Gender differences and burden of chronic conditions: impact on quality of life among the elderly in Taiwan.
CONCLUSIONS: Our findings suggest that women tend to report that their physical health-related QoL is poorer than that of men, and such a difference does not seem to be attributable to the distribution of chronic conditions. Elderly men and women may perceive health-related QoL differently. PMID: 30604210 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - January 2, 2019 Category: Geriatrics Authors: Yu T, Enkh-Amgalan N, Zorigt G, Hsu YJ, Chen HJ, Yang HY Tags: Aging Clin Exp Res Source Type: research

Can Fish Oil Help Reading?
Discussion Fats and fatty acids are essential for good human health. Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet. Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature. Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Source: PediatricEducation.org - November 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Obesity Prevention Resources for Special Populations
From the NLM Outreach and Special Populations Branch: Obesity is a major health issue in the United States, and the Centers for Disease Control and Prevention (CDC) offer some alarming facts about obesity in both adults and children in the US: Obesity affects about 1 in 6 children in the US. More than 1/3 of US adults are obese. The highest age-adjusted rates of obesity impact African Americans (48.1%) followed by Hispanic Americans (42.5%). Obesity can put an individual at increased risk for diabetes, heart disease, stroke, arthritis, and some cancers. Changes in nutrition and exercise habits can help to prevent obes...
Source: NN/LM Middle Atlantic Region Blog - July 5, 2017 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Consumer Health Education Public Health Source Type: news

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