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A Comparison of Three Different Bioinformatics Analyses of the 16S –23S rRNA Encoding Region for Bacterial Identification
Conclusion The higher resolution at the species level identification provided by 16S–23S rRNA encoding region NGS makes its use in routine diagnostic microbiology potentially attractive. Particularly, data analysis is one of the most important steps of a diagnostic workflow, which requires an optimal pipeline for the interpretation of the sequencing data in a short time. This study demonstrates that de novo assembly and subsequent BLASTN analysis using an in-house developed database compared to OTU clustering and mapping approaches is the most accurate and fastest approach for identification of bacterial pathogens....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Clinical - microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India.
CONCLUSIONS: This study reiterates the persistent dominance of rheumatic heart disease in the population studied and α - hemolytic Streptococci as the commonest responsible microorganism. PMID: 29716704 [PubMed - in process]
Source: Indian Heart J - March 1, 2018 Category: Cardiology Authors: Subbaraju P, Rai S, Morakhia J, Midha G, Kamath A, Saravu K Tags: Indian Heart J Source Type: research

Infective Endocarditis at a Hospital in Saudi Arabia: Epidemiology, Bacterial Pathogens and Outcome
CONCLUSION: Native valve endocarditis is the predominant type of endocarditis. The patients were older adults and the most common organisms wereSaureus, E faecalis and viridans streptococci. Ann Saudi Med 2009; 29(6): 433-436
Source: Annals of Saudi Medicine - November 18, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Ischemic stroke and ST-elevation myocardial infarction revealing infective endocarditis.
Authors: Joliat GR, Halkic N, Pantet O, Ben-Hamouda N Abstract In this clinical scenario, we report the case of a patient who presented multiple embolic complications due to mitral infective endocarditis (IE). A 68-year-old woman had extended right hepatectomy for hilar cholangiocarcinoma. Unfortunately, she had multiple postoperative complications and had to be transferred to the Intensive Care Unit. During this stay, we have diagnosed an Enterococcus faecium IE after the occurrence of multiple embolic complications (myocardial infarction, ischemic stroke, digital emboli, splenic emboli, and renal emboli). The cas...
Source: European Review for Medical and Pharmacological Sciences - November 14, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Clinical – microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India
CONCLUSIONS This study reiterates the persistent dominance of rheumatic heart disease in the population studied and α − haemolytic Streptococci as the commonest responsible microorganism.
Source: Indian Heart Journal - August 17, 2017 Category: Cardiology Source Type: research