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Condition: Hemorrhagic Stroke

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Total 19785 results found since Jan 2013.

Recurrent Ischemic Lesions After Acute Atherothrombotic Stroke: Clopidogrel Plus Aspirin Versus Aspirin Alone Clinical Sciences
Conclusions— Clopidogrel plus aspirin might not be superior to aspirin alone for preventing new ischemic lesion and clinical vascular events in patients with acute ischemic stroke caused by large artery atherosclerosis. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00814268.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Hong, K.-S., Lee, S.-H., Kim, E. G., Cho, K.-H., Chang, D. I., Rha, J.-H., Bae, H.-J., Lee, K. B., Kim, D. E., Park, J.-M., Kim, H.-Y., Cha, J.-K., Yu, K.-H., Lee, Y.-S., Lee, S. J., Choi, J. C., Cho, Y.-J., Kwon, S. U., Kim, G.-M., Sohn, S.-I., Park, K.- Tags: Ischemic Stroke Clinical Sciences Source Type: research

Development of a Mobile Tool That Semiautomatically Screens Patients for Stroke Clinical Trials Brief Reports
Conclusions— We created a semiautomated electronic screening tool that uses branch logic to screen patients for stroke clinical trials. The tool has improved efficiency and efficacy of screening, and it could be adapted for use at other sites and in other medical fields.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Spokoyny, I., Lansberg, M., Thiessen, R., Kemp, S. M., Aksoy, D., Lee, Y., Mlynash, M., Hirsch, K. G. Tags: Clinical Studies, Health Services, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Neurorestorative Responses to Delayed Human Mesenchymal Stromal Cells Treatment of Stroke in Type 2 Diabetic Rats Basic Sciences
Conclusions—In T2DM stroke rats, delayed hMSC treatment significantly improves neurological functional outcome and increases neurorestorative effects and M2 macrophage polarization. Increasing brain platelet-derived growth factor expression may contribute to hMSC-induced neurorestoration.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Yan, T., Venkat, P., Chopp, M., Zacharek, A., Ning, R., Roberts, C., Zhang, Y., Lu, M., Chen, J. Tags: Cell Therapy, Stem Cells, Diabetes, Type 2, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke Basic Sciences
Conclusions—In addition to its benefits in infarct size reduction, 12/15-LOX inhibition also may independently reduce HT in warfarin-treated mice. ML351 should be further evaluated as stroke treatment in anticoagulated patients suffering a stroke, either alone or in conjunction with tissue-type plasminogen activator.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Yu Liu, Yi Zheng, Hulya Karatas, Xiaoying Wang, Christian Foerch, Eng H. Lo, Klaus van Leyen Tags: Blood-Brain Barrier, Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Association Between Acute Kidney Disease and Intravenous Dye Administration in Patients With Acute Stroke Clinical Sciences
Conclusions—Although 22% of patients in the Greater Cincinnati/Northern Kentucky stroke population had unsuspected kidney disease, the incidence of new or worsening kidney disease was low, and AKI was not associated with dye administration. These findings confirm single-center reports that the risk of severe renal complications after contrast dye is small.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Stacie L. Demel, Aaron W. Grossman, Jane C. Khoury, Charles J. Moomaw, Kathleen Alwell, Brett M. Kissela, Daniel Woo, Matthew L. Flaherty, Simona Ferioli, Jason Mackey, Felipe De Los Rios la Rosa, Sharyl Martini, Opeolu Adeoye, Dawn O. Kleindorfer Tags: Epidemiology, Computerized Tomography (CT), Imaging, Complications, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Delays in Door-to-Needle Times and Their Impact on Treatment Time and Outcomes in Get With The Guidelines-Stroke Clinical Sciences
Conclusions—Hospital and eligibility delays such as delay diagnosis and inability to determine eligibility were associated with longer door-to-needle times. Improved stroke recognition and management of acute comorbidities may help to reduce door-to-needle times.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Noreen Kamal, Shubin Sheng, Ying Xian, Roland Matsouaka, Michael D. Hill, Deepak L. Bhatt, Jeffrey L. Saver, Mathew J. Reeves, Gregg C. Fonarow, Lee H. Schwamm, Eric E. Smith Tags: Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—We found no evidence for effect modification of intra-arterial treatment by admission serum glucose in patients with acute ischemic stroke.Clinical Trial Registration—URL: www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Elizabeth Osei, Heleen M. den Hertog, Olvert A. Berkhemer, Puck S.S. Fransen, Yvo B.W.E.M. Roos, Debbie Beumer, Robert J. van Oostenbrugge, Wouter J. Schonewille, Jelis Boiten, Adrienne A.M. Zandbergen, Peter J. Koudstaal, Diederik W.J. Dippel Tags: Revascularization, Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis Clinical Sciences
Background and Purpose—Significance and management of blood pressure (BP) changes in acute stroke care are unclear. Here, we aimed to investigate the impact of 24-hour BP variability (BPV) on outcome in patients with acute ischemic stroke treated with intravenous thrombolysis.Methods—From the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis registry, 28 976 patients with documented pre-treatment systolic BP at 2 and 24 hours were analyzed. The primary measure of BP variability was successive variability. Data were preprocessed using coarsened exact matching. We assessed early neurological ...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Lars Kellert, Christian Hametner, Niaz Ahmed, Geraldine Rauch, Mary J. MacLeod, Francesco Perini, Kennedy R. Lees, Peter A. Ringleb Tags: Ischemic Stroke Original Contributions Source Type: research

Real-World Setting Comparison of Nonvitamin-K Antagonist Oral Anticoagulants Versus Vitamin-K Antagonists for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Conclusions—This meta-analysis confirms the main findings of the randomized controlled trials of dabigatran, rivaroxaban, and apixaban in the real-world setting and, hence, strengthens their validity.
Source: Stroke - August 28, 2017 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, Gregory Y.H. Lip Tags: Arrhythmias, Secondary Prevention, Meta Analysis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke Brief Report
Conclusions—Mechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Kunakorn Atchaneeyasakul, Thabele Leslie-Mazwi, Kathleen Donahue, Anne-Katrin Giese, Natalia S. Rost Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

PROMIS GH (Patient-Reported Outcomes Measurement Information System Global Health) Scale in Stroke Clinical Sciences
The objective of this study was to evaluate the psychometric properties of PROMIS GH in patients with ischemic stroke and intracerebral hemorrhage.Methods—PROMIS GH and 6 PROMIS domain scales measuring same/similar constructs were electronically collected on 1102 patients with ischemic and hemorrhagic strokes at various stages of recovery from their stroke who were seen in a cerebrovascular clinic from October 12, 2015, through June 2, 2017. Confirmatory factor analysis was performed to evaluate the adequacy of 2-factor structure of component scores. Test–retest reliability and convergent validity of PROMIS GH items an...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Irene L. Katzan, Brittany Lapin Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Taurine Reduces tPA (Tissue-Type Plasminogen Activator)-Induced Hemorrhage and Microvascular Thrombosis After Embolic Stroke in Rat Basic Sciences
Conclusions—Our results suggest that taurine in combination with tPA may be a clinically feasible approach toward future attempts at combination stroke therapy.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Shan Liu, Min Wang, Guohong Li Tags: Animal Models of Human Disease, Ischemic Stroke Original Contributions Source Type: research

Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage Clinical Sciences
Conclusions— This pathway analysis demonstrates association between common genetic variants within OXPHOS genes and stroke. The associations for small vessel stroke and deep ICH suggest that genetic variation in OXPHOS influences small vessel pathobiology. Further studies are needed to identify culprit genetic variants and assess their functional consequences.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Anderson, C. D., Biffi, A., Nalls, M. A., Devan, W. J., Schwab, K., Ayres, A. M., Valant, V., Ross, O. A., Rost, N. S., Saxena, R., Viswanathan, A., Worrall, B. B., Brott, T. G., Goldstein, J. N., Brown, D., Broderick, J. P., Norrving, B., Greenberg, S. M Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Brain Circulation and Metabolism, Genetics of Stroke Clinical Sciences Source Type: research

External Validation of the SEDAN Score for Prediction of Intracerebral Hemorrhage in Stroke Thrombolysis Clinical Sciences
Conclusions— In this very large data set, the predictive and discriminatory performances of the SEDAN score were only moderate for SICH per ECASS II and low for SICH per SITS–Monitoring Study.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Mazya, M. V., Bovi, P., Castillo, J., Jatuzis, D., Kobayashi, A., Wahlgren, N., Ahmed, N. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research