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Condition: Hemorrhagic Stroke

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Total 19785 results found since Jan 2013.

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review Clinical Sciences
Background and Purpose—In patients with transient ischemic attack/ischemic stroke, microbleed burden predicts intracerebral hemorrhage (ICH), and ischemic stroke, but implications for antiplatelet treatment are uncertain. Previous cohort studies have had insufficient follow-up to assess the time course of risks, have not stratified risks by antithrombotic use, and have not reported extracranial bleeds or functional outcome of ICH versus ischemic stroke.Methods—In 2 independent prospective cohorts with transient ischemic attack/ischemic stroke (Oxford Vascular Study/mainly white; University of Hong Kong/mainly Chinese),...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Kui Kai Lau, Caroline E. Lovelock, Linxin Li, Michela Simoni, Sergei Gutnikov, Wilhelm Kuker, Henry Ka Fung Mak, Peter M. Rothwell Tags: Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Stroke-Related Early Tracheostomy Versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): A Randomized Pilot Trial Original Contributions
Conclusions— Early tracheostomy in ventilated intensive care stroke patients is feasible, and safe, and presumably reduces sedation need. Whether the suggested benefits in mortality and outcome truly exist has to be determined by a larger multicenter trial. Clinical Trial Registration— http://www.clinicaltrials.gov. Unique identifier: NCT01261091.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Bosel, J., Schiller, P., Hook, Y., Andes, M., Neumann, J.-O., Poli, S., Amiri, H., Schonenberger, S., Peng, Z., Unterberg, A., Hacke, W., Steiner, T. Tags: Other Treatment, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Other Stroke Treatment - Surgical Original Contributions Source Type: research

Subarachnoid Hemorrhage in a Multimodal Approach Heavily Weighted Toward Mechanical Thrombectomy With Solitaire Stent in Acute Stroke Original Contributions
Conclusions— SAH on post-therapeutic computerized tomography scans were not uncommon after primary mechanical thrombectomy with a Solitaire stent, but they seemed to be benign. Rescue angioplasty and unidentified, small vessel ruptures due to mechanical stretch during stent retrieval might give rise to these lesions.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Yoon, W., Jung, M. Y., Jung, S. H., Park, M. S., Kim, J. T., Kang, H. K. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Intracerebral Hemorrhage Original Contributions Source Type: research

High-density Lipoprotein-based Therapy Reduces the Hemorrhagic Complications Associated With Tissue Plasminogen Activator Treatment in Experimental Stroke Clinical Sciences
Conclusions— HDL injection decreased tPA-induced hemorrhagic transformation in rat models of MCAO. Both in vivo and in vitro results support the vasculoprotective action of HDLs on BBB under ischemic conditions.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Lapergue, B., Dang, B. Q., Desilles, J.-P., Ortiz-Munoz, G., Delbosc, S., Loyau, S., Louedec, L., Couraud, P.-O., Mazighi, M., Michel, J.-B., Meilhac, O., Amarenco, P. Tags: Lipids, Animal models of human disease, Acute Cerebral Infarction, Emergency treatment of Stroke, Neuroprotectors, Thrombolysis, Endothelium/vascular type/nitric oxide Clinical Sciences Source Type: research

Systolic Blood Pressure After Intravenous Antihypertensive Treatment and Clinical Outcomes in Hyperacute Intracerebral Hemorrhage: The Stroke Acute Management With Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study Clinical Sciences
Conclusions— High achieved SBP after standardized antihypertensive therapy in hyperacute intracerebral hemorrhage was independently associated with poor clinical outcomes. Aggressive antihypertensive treatment may ameliorate clinical outcomes.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Sakamoto, Y., Koga, M., Yamagami, H., Okuda, S., Okada, Y., Kimura, K., Shiokawa, Y., Nakagawara, J., Furui, E., Hasegawa, Y., Kario, K., Arihiro, S., Sato, S., Kobayashi, J., Tanaka, E., Nagatsuka, K., Minematsu, K., Toyoda, K., for the SAMURAI Study Inv Tags: Cerebrovascular disease/stroke, CT and MRI, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Prospective, Multicenter, Single-Arm Study of Mechanical Thrombectomy Using Solitaire Flow Restoration in Acute Ischemic Stroke Clinical Sciences
Conclusions— In this single-arm study, treatment with the Solitaire Flow Restoration device in intracranial anterior circulation occlusions results in high rates of revascularization, low risk of clinically relevant procedural complications, and good clinical outcomes in combination with low mortality at 90 days. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01327989.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Pereira, V. M., Gralla, J., Davalos, A., Bonafe, A., Castano, C., Chapot, R., Liebeskind, D. S., Nogueira, R. G., Arnold, M., Sztajzel, R., Liebig, T., Goyal, M., Besselmann, M., Moreno, A., Schroth, G. Tags: Emergency treatment of Stroke Clinical Sciences Source Type: research

THRIVE Score Predicts Ischemic Stroke Outcomes and Thrombolytic Hemorrhage Risk in VISTA Clinical Sciences
Conclusions— The THRIVE score is a simple-to-use tool to predict clinical outcome, mortality, and risk of hemorrhage after thrombolysis in patients with ischemic stroke. Despite its simplicity, the THRIVE score performs better than several other outcome prediction tools. A free Web calculator for the THRIVE score is available at http://www.thrivescore.org.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Flint, A. C., Faigeles, B. S., Cullen, S. P., Kamel, H., Rao, V. A., Gupta, R., Smith, W. S., Bath, P. M., Donnan, G. A., on behalf of the VISTA Collaboration, VISTA Steering Committee (VISTA-Acute) members, Lees, Alexandrov, Bath, Bluhmki, Bornstein, Cla Tags: Emergency treatment of Stroke Clinical Sciences Source Type: research

CLOTBUST-Hands Free: Pilot Safety Study of a Novel Operator-Independent Ultrasound Device in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions— Sonothrombolysis using a novel, operator-independent device, in combination with systemic tPA, seems safe, and recanalization rates warrant evaluation in a phase III efficacy trial. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: CLOTBUST-HF NCT01240356.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Barreto, A. D., Alexandrov, A. V., Shen, L., Sisson, A., Bursaw, A. W., Sahota, P., Peng, H., Ardjomand-Hessabi, M., Pandurengan, R., Rahbar, M. H., Barlinn, K., Indupuru, H., Gonzales, N. R., Savitz, S. I., Grotta, J. C. Tags: Acute Cerebral Infarction, Doppler ultrasound, Transcranial Doppler etc., Thrombolysis, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Impact of Pretreatment Noncontrast CT Alberta Stroke Program Early CT Score on Clinical Outcome After Intra-Arterial Stroke Therapy Clinical Sciences
Conclusions— NCCT seems useful for excluding patients with the greatest burden of ischemic damage from futile intra-arterial treatment, which is unlikely to result in patient functional independence and increases the risk of hemorrhage.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Yoo, A. J., Zaidat, O. O., Chaudhry, Z. A., Berkhemer, O. A., Gonzalez, R. G., Goyal, M., Demchuk, A. M., Menon, B. K., Mualem, E., Ueda, D., Buell, H., Sit, S. P., Bose, A., on behalf of the Penumbra Pivotal and Penumbra Imaging Collaborative Study (PICS Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Different Doses of Recombinant Tissue-Type Plasminogen Activator for Acute Stroke in Chinese Patients Clinical Sciences
Conclusions— These results did not support the dose of 0.9 mg/kg of r-tPA being optimal for all patients in the East Asian population. In elderly patients (71–80 years), a lower dose of 0.6 mg/kg is associated with a better outcome. Confirmation of the results through randomized trial is required.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Chao, A.-C., Liu, C.-K., Chen, C.-H., Lin, H.-J., Liu, C.-H., Jeng, J.-S., Hu, C.-J., Chung, C.-P., Hsu, H.-Y., Sheng, W.-Y., Hu, H.-H., on behalf of the Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group Tags: Thrombolysis Clinical Sciences Source Type: research

Hemorrhagic Stroke and Cerebral Paragonimiasis Brief Reports
Conclusions— Hemorrhagic stroke typically occurred during the acute stage and in the early stages of further Paragonimus migration. Delay of treatment increased the risk of initial and recurrent stroke.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Xia, Y., Ju, Y., Chen, J., You, C. Tags: Acute Cerebral Hemorrhage, Computerized tomography and Magnetic Resonance Imaging, Primary and Secondary Stroke Prevention, Risk Factors for Stroke Brief Reports Source Type: research

Influence of Age on Clinical and Revascularization Outcomes in the North American Solitaire Stent-Retriever Acute Stroke Registry Clinical Sciences
Conclusion— Greater than 80 years of age is predictive of poor clinical outcome and increased mortality compared with younger patients in the NASA registry. However, intravenous tissue-type plasminogen activator use, lower NIHSS, and shorter revascularization time are associated with better outcomes. Further studies are needed to understand the endovascular therapy role in this cohort compared with medical therapy.
Source: Stroke - November 24, 2014 Category: Neurology Authors: Castonguay, A. C., Zaidat, O. O., Novakovic, R., Nguyen, T. N., Taqi, M. A., Gupta, R., Sun, C.-H. J., Martin, C., Holloway, W. E., Mueller-Kronast, N., E. English, J., Linfante, I., Dabus, G., Malisch, T. W., Marden, F. A., Bozorgchami, H., Xavier, A., R Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Relevance of Blood-Brain Barrier Disruption After Endovascular Treatment of Ischemic Stroke: Dual-Energy Computed Tomographic Study Clinical Sciences
Conclusions— Blood–brain barrier disruption, defined as CS and BH on dual-energy CT, was associated with poor clinical outcomes in patients with stroke treated with endovascular therapies. Moreover, isolated CS was associated with delayed hemorrhagic transformation. These results support the clinical relevance of blood–brain barrier disruption in acute stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Renu, A., Amaro, S., Laredo, C., Roman, L. S., Llull, L., Lopez, A., Urra, X., Blasco, J., Oleaga, L., Chamorro, A. Tags: Cerebrovascular disease/stroke, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
Conclusions— Intracerebral hemorrhage remains a serious condition for which early aggressive care is warranted. These guidelines provide a framework for goal-directed treatment of the patient with intracerebral hemorrhage.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Hemphill, J. C., Greenberg, S. M., Anderson, C. S., Becker, K., Bendok, B. R., Cushman, M., Fung, G. L., Goldstein, J. N., Macdonald, R. L., Mitchell, P. H., Scott, P. A., Selim, M. H., Woo, D., on behalf of the American Heart Association Stroke Council, Tags: AHA Statements and Guidelines AHA/ASA Guideline Source Type: research

Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke-Full Dose Regimen Stroke Trial Clinical Sciences
Conclusions— These results demonstrate comparable safety of full-dose r-tPA plus eptifibatide with historical rates of sICH with r-tPA alone and support proceeding with a phase 3 trial evaluating full-dose r-tPA combined with eptifibatide to improve outcomes after AIS.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Adeoye, O., Sucharew, H., Khoury, J., Vagal, A., Schmit, P. A., Ewing, I., Levine, S. R., Demel, S., Eckerle, B., Katz, B., Kleindorfer, D., Stettler, B., Woo, D., Khatri, P., Broderick, J. P., Pancioli, A. M. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research