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Total 202 results found since Jan 2013.

Evaluation After a First Seizure in Adults
Am Fam Physician. 2022 May 1;105(5):507-513.ABSTRACTSeizures are transient signs and symptoms of abnormal, excessive, or synchronous neuronal activity in the brain. Up to 10% of adults have a seizure during their lifetime, with increasing incidence in people older than 55 years. One-third of people have a recurrent seizure within one year of an initial unprovoked seizure. Acute symptomatic (provoked) seizures recur less often, especially when provoking factors are addressed. After confirming a probable seizure, evaluation focuses on identifying provoking factors such as tumor, metabolic derangement, infectious disease, str...
Source: American Family Physician - May 13, 2022 Category: Primary Care Authors: Kate Rowland Carl Earl Lambert Source Type: research

Imaging subtle leaks in the blood –brain barrier in the aging human brain: potential pitfalls, challenges, and possible solutions
AbstractRecent studies using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with gadolinium-based contrast agents (GBCA) have demonstrated subtle blood –brain barrier (BBB) leaks in the human brain during normal aging, in individuals with age-related cognitive dysfunction, genetic risk for Alzheimer’s disease (AD), mild cognitive impairment, early AD, cerebral small vessel disease (SVD), and other neurodegenerative disorders. In these neurologi cal conditions, the BBB leaks, quantified by the unidirectional BBB GBCA tracer’s constantKtrans maps, are typically orders of magnitude lower than in brain tu...
Source: AGE - April 25, 2022 Category: Geriatrics Source Type: research

Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation for Post-stroke Vascular Cognitive Impairment: A Prospective Pilot Study
ConclusionsHigh-frequency rTMS on the ipsilesional DLPFC may exert immediate efficacy on cognition with the anti-inflammatory response and changes in brain network in PSCI, lasting at least 3 months.
Source: Frontiers in Neurology - March 22, 2022 Category: Neurology Source Type: research

Verbal and memory deficits caused by aphasic status epilepticus after resection of a left temporal lobe glioma
CONCLUSION: Prolonged ASE can induce verbal and memory deficits. Early intervention with intravenous anesthetics is required to obtain a favorable neurological prognosis.PMID:34992930 | PMC:PMC8720448 | DOI:10.25259/SNI_1120_2021
Source: Surgical Neurology International - January 7, 2022 Category: Neurosurgery Authors: Misaki Kamogawa Naoki Ikegaya Yohei Miyake Takahiro Hayashi Hidetoshi Murata Kensuke Tateishi Tetsuya Yamamoto Source Type: research