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Total 128 results found since Jan 2013.
Do we have to age?
The biologist Andrew Steele thinks ageing is a disease that can be treated. But if we had a cure for getting old, what would that mean for us?When the biologist Andrew Steele tells people his thoughts on ageing – that we might one day cure it as if it were any other disease – they are often incredulous and sometimes hostile. Once, at a friend’s wedding, he left a group of guests mildly incensed for suggesting that near-future humans might live well into their 100s. A similar thing happens at dinner p arties, where the responses are more polite but no less sceptical. He understands the reaction. We think of ageing as ...
Source: Guardian Unlimited Science - January 3, 2021 Category: Science Authors: Alex Moshakis Tags: Ageing Life and style Science Source Type: news
Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations Biophysics and Computational Biology
The voltage-gated Hv1 proton channel is a ubiquitous membrane protein that has roles in a variety of cellular processes, including proton extrusion, pH regulation, production of reactive oxygen species, proliferation of cancer cells, and increased brain damage during ischemic stroke. A crystal structure of an Hv1 construct in a putative...
Source: Proceedings of the National Academy of Sciences - June 15, 2020 Category: Science Authors: Andrew D. Geragotelis, Mona L. Wood, Hendrik Goddeke, Liang Hong, Parker D. Webster, Eric K. Wong, J. Alfredo Freites, Francesco Tombola, Douglas J. Tobias Tags: Biological Sciences Source Type: research
How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer.
My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true.
Seven years ...
Source: TIME: Science - November 20, 2019 Category: Science Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news
Air pollution kills five people in Bristol each week, study shows
Toxic air contributes to health conditions such as asthma, cancer and stroke, say expertsFive people die each week in Bristol as a result of high levels of air pollution, a study has revealed.Researchers at King ’s College London examined the combined impact of PM2.5, which is mainly from domestic wood and coal burning and industrial combustion and nitrogen dioxide, which mainly comes from older polluting vehicles.Continue reading...
Source: Guardian Unlimited Science - November 18, 2019 Category: Science Authors: Sandra Laville Tags: Air pollution Bristol Environment UK news Science King's College London Education Higher education Cities Source Type: news
The Director of the NIH Lays Out His Vision of the Future of Medical Science
Our world has never witnessed a time of greater promise for improving human health. Many of today’s health advances have stemmed from a long arc of discovery that begins with strong, steady support for basic science. In large part because of fundamental research funded by the National Institutes of Health (NIH), which traces its roots to 1887, Americans are living longer, healthier lives. Life expectancy for a baby born in the U.S. has risen from 47 years in 1900 to more than 78 years today. Among the advances that have helped to make this possible are a 70% decline in the U.S. death rate from cardiovascular disease ...
Source: TIME: Science - October 24, 2019 Category: Science Authors: Dr. Francis S. Collins Tags: Uncategorized Healthcare medicine Source Type: news
In vitro antioxidant, 𝛼-amylase and 𝛼-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Olubunmi Adenike Akinwunmi Source Type: research
In vitro antioxidant, α-amylase and α-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Oubunmi Adenike Akinwunmi Source Type: research
Heavily processed food like ready meals and ice-cream linked to early death
Two major studies add to body of evidence against foods made with industrial ingredientsPeople who eat large amounts of heavily processed foods, from breakfast cereals and ready meals to muffins and ice-cream, have a greater risk of heart attack, stroke and early death, according to two major studies.The findings, from separate teams in France and Spain, add to a growing body of evidence that foods made in factories with industrial ingredients may have a hand in an array of medical disorders such as cancer, obesity and high blood pressure.Continue reading...
Source: Guardian Unlimited Science - May 30, 2019 Category: Science Authors: Ian Sample Science editor Tags: Science Health Diets and dieting Food Obesity Heart disease Life and style Source Type: news
PAC, an evolutionarily conserved membrane protein, is a proton-activated chloride channel
Severe local acidosis causes tissue damage and pain, and is one of the hallmarks of many diseases including ischemia, cancer, and inflammation. However, the molecular mechanisms of the cellular response to acid are not fully understood. We performed an unbiased RNA interference screen and identified PAC (TMEM206) as being essential for the widely observed proton-activated Cl– (PAC) currents (ICl,H). Overexpression of human PAC in PAC knockout cells generated ICl,H with the same characteristics as the endogenous ones. Zebrafish PAC encodes a PAC channel with distinct properties. Knockout of mouse Pac abolished ICl,H i...
Source: ScienceNOW - April 24, 2019 Category: Science Authors: Yang, J., Chen, J., del Carmen Vitery, M., Osei-Owusu, J., Chu, J., Yu, H., Sun, S., Qiu, Z. Tags: Cell Biology reports Source Type: news
Lowering Your Blood Pressure Could Reduce Alzheimer ’s Risk, New Research Shows
Margaret Daffodil Graham tries to live a healthy life, particularly since she has a health issue that requires constant attention. Like more than 100 million other Americans, the 74-year-old from Winston-Salem, N.C., has high blood pressure, and she has been taking medication to control it since she was in her 30s. So when she read that her nearby hospital, Wake Forest Baptist Medical Center, was looking for people with hypertension to volunteer for a study, she quickly signed up, knowing the doctors would monitor her blood pressure more intensively and hopefully lower her risk of developing heart disease and stroke.
What...
Source: TIME: Science - August 9, 2018 Category: Science Authors: Alice Park Tags: Uncategorized Aging Alzheimer's Research Source Type: news
New 'unified theory' of childhood leukemia raises possibility of preventing the disease
Kids who develop acute lymphoblastic leukemia may be the victims of a triple-whammy stroke of bad luck, according to a provocative new theory from a respected British cancer researcher.If the explanation turns out to be correct, it would be good news for the most common type of childhood cancer:...
Source: Los Angeles Times - Science - May 23, 2018 Category: Science Authors: Melissa Healy Source Type: news
Tax sugar, alcohol and tobacco to help the poor, say experts
On the eve of the UK introduction of a sugary drinks levy, experts urge global adoption of ‘sin taxes’ to deter unhealthy habits and check the spread of diseaseSo called “sin taxes” on sugary drinks, alcohol and tobacco not only work, but will help rather than unduly penalise the poor, according to a major new international analysis.Just a day before the UK brings in a levy on sugary drinks, experts are urging every country in the world to use taxes to deter people from the eating, drinking and smoking habits that will damage their health. They warn of the urgent need to check the spread of cancers, diabetes, heart...
Source: Guardian Unlimited Science - April 4, 2018 Category: Science Authors: Sarah Boseley Health editor Tags: Sugar Science Obesity Health Society Source Type: news
Let us Break the Heart Attack Related Myths in Women on the Eve of International Women ’s Day
Several myths surrounding heart diseases state that heart diseases attract only elder people and more men than women are prone to heart attacks. Contrary to the belief, cardiovascular cases are on rise in women than men and it is deadlier than all forms of cancers combined. Both physiological and psychological factors are causing heart diseases and it affects people of all ages with no bias. Women that have suffered from mental illness are more susceptible to attract heart risks like stroke. Mental ill health like schizophrenia, anxiety disorders and bipolar disorders are mostly treated with antidepressants, antipsychotics...
Source: Sciences Blog - March 9, 2018 Category: Science Authors: srinivas_s at omicsgroup.co.in (OMICS Publishing Group) Tags: OMICS Anxiety Disorders bipolar disorders cardiovascular cases heart attacks heart diseases psychological factors Source Type: blogs
Does dry January work? We ask the experts
Millions pledge to start the new year alcohol-free, but how much difference can a month off booze make to our health or drinking behaviour in the long term?Read more:‘I now sleep straight through until my alarm rings’: your experiences of dry JanuaryMillions of people pledge to ditch the booze every January, but experts are divided over whether going dry for a month is the answer to the UK ’s troubled relationship with alcohol.According torecent figures, around four-fifths of adults drink in England, with 31% of all men and 16% of all women consuming more than therecommended limit of 14 units in a usual week. As well...
Source: Guardian Unlimited Science - January 19, 2018 Category: Science Authors: Nicola Davis Tags: Alcohol Alcoholism Health Society & wellbeing Life and style Source Type: news
