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Total 212 results found since Jan 2013.

First In Vivo Potassium-39 K) MRI at 9.4 T Using Conventional Copper Radio Frequency Surface Coil Cooled to 77 K
Potassium-39 ( 39K) magnetic resonance imaging (MRI) is a noninvasive technique which could potentially allow for detecting intracellular physiological variations in common human pathologies such as stroke and cancer. However, the low signal-to-noise ratio (SNR) achieved in 39K-MR images hampered data acquisition with sufficiently high spatial and temporal resolution in animal models so far. Full wave electromagnetic (EM) simulations were performed for a single-loop copper (Cu) radio frequency (RF) surface resonator with a diameter of 30 mm optimized for rat brain imaging at room temperature (RT) and at liquid nitrogen (LN...
Source: IEEE Transactions on Biomedical Engineering - February 1, 2014 Category: Biomedical Engineering Source Type: research

First In Vivo Potassium-39 $(^{bf 39}$K) MRI at 9.4 T Using Conventional Copper Radio Frequency Surface Coil Cooled to 77 K
Potassium-39 ($^{39}$K) magnetic resonance imaging (MRI) is a noninvasive technique which could potentially allow for detecting intracellular physiological variations in common human pathologies such as stroke and cancer. However, the low signal-to-noise ratio (SNR) achieved in $^{39}$K-MR images hampered data acquisition with sufficiently high spatial and temporal resolution in animal models so far. Full wave electromagnetic (EM) simulations were performed for a single-loop copper (Cu) radio frequency (RF) surface resonator with a diameter of 30 mm optimized for rat brain imaging at room temperature (RT) and at liq...
Source: IEEE Transactions on Biomedical Engineering - January 17, 2014 Category: Biomedical Engineering Source Type: research

Dementia research funding should be on same footing as cancer, says charity
This article was amended on Wednesday 11 December 2013. Alzheizmer's Research Trust is now called Alzheimer's Research UK. This has been corrected.DementiaMental healthMedical researchHaroon Siddiquetheguardian.com © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds
Source: Guardian Unlimited Science - December 11, 2013 Category: Science Authors: Haroon Siddique Tags: The Guardian Mental health News Medical research Society Dementia UK news Science Source Type: news

Scan could detect those on brink of heart attack
Conclusion This is a valuable study which shows the promise of using PET-CT with radioactively labelled sodium fluoride (NaF) as a way of identifying fatty deposits in the heart arteries that could be at risk of rupturing and causing a heart attack. The results confirmed that the marker used in this study (NaF) was better than the chemical marker normally used in PET-CT scans (FDG). The technique has the principal value of being a non-invasive technique compared with coronary angiography, which is the standard method used to look at blockages in heart arteries. As it does not involve surgical intervention, this could ha...
Source: NHS News Feed - November 11, 2013 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

A nationwide population-based retrospective cohort study: increased risk of acute coronary syndrome in patients with ankylosing spondylitis.
Conclusions: AS patients are at higher risk of ACS compared with non-AS subjects. Management of CV risk factors should be taken into account for the treatment of patients with AS, especially for patients with co-morbidities of hypertension, DM, and cancer. PMID: 24134400 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - October 18, 2013 Category: Rheumatology Authors: Chou CH, Lin MC, Peng CL, Wu YC, Sung FC, Kao CH, Liu SH Tags: Scand J Rheumatol Source Type: research

Autoimmune gabab antibody encephalitis associated with non-malignant lung lesion
GABAb receptor autoimmune encephalitis is a potentially treatable disorder characterised by seizures, memory deficits, increased anxiety and mood dysregulation. In some patients it is associated with small–cell lung cancer and with other autoantibodies. We are presenting a case of GABAb receptor autoimmune encephalitis which was associated with non–malignant lung lesion, likely inflammatory in nature. A 62 year old woman presented with recent onset depression and tonic–clonic seizures. CT head showed patchy white matter changes particularly in the left frontal lobe. Initial treatment for suspected infecti...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Wysota, B., Teare, L., Karim, A., Jacob, S. Tags: Immunology (including allergy), Epilepsy and seizures, Infection (neurology), Stroke, Drugs: psychiatry, Memory disorders (psychiatry), Radiology, Drugs: musculoskeletal and joint diseases, Radiology (diagnostics) Association of British Neurologists (AB Source Type: research

A stroke mimic; focal neurological deficits in benign hereditary chorea?
Conclusion This case highlights the difficulties in assessing patients with new focal neurological symptoms in the presence of known, pre existing, neurological disease. It also serves to highlight how often erroneously progressive weakness is mislabelled as a ‘stroke’. Neurologists working together with acute physicians in liaison posts in MAU, provides a unique opportunity to improve overall recognition of neurological disease, and for patients potentially provides a more timely diagnostic work–up and the opportunity for early treatment.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Maw, K., Johnston, J., Rowntree, C., Kalhan, A. Tags: Immunology (including allergy), Headache (including migraine), Movement disorders (other than Parkinsons), Neurooncology, Pain (neurology), Stroke, CNS cancer, Neuropathology, Radiology, Surgical diagnostic tests, Surgical oncology Association of Britis Source Type: research

Systemic treatments for the prevention of venous thrombo-embolic events in paediatric cancer patients with tunnelled central venous catheters.
CONCLUSIONS: We found no significant effects of systemic treatments compared with no intervention in preventing (a)symptomatic VTE in paediatric oncology patients with CVCs. However, this could be a result of the low number of included participants, which resulted in low power. In one CCT, which compared one systemic treatment with another systemic treatment, we identified a significant reduction in symptomatic VTE with the addition of LMWH to AT supplementation.All studies investigated the prevalence of major and/or minor bleeding episodes, and none found a significant difference between study groups. None of the studies ...
Source: Cochrane Database of Systematic Reviews - September 11, 2013 Category: Journals (General) Authors: Schoot RA, Kremer LC, van de Wetering MD, van Ommen CH Tags: Cochrane Database Syst Rev Source Type: research

MR compatible positioning device for guiding a focused ultrasound system for the treatment of brain deseases
ConclusionA simple, cost effective, portable positioning device has been developed which can be used in virtually any clinical MRI scanner since it can be placed on the table of the MRI scanner. This system can be used to treat in the future patients with brain cancer and ischemic stroke. Copyright © 2013 John Wiley & Sons, Ltd.
Source: The International Journal of Medical Robotics and Computer Assisted Surgery - June 7, 2013 Category: Surgery Authors: N. Mylonas, C. Damianou Tags: Original Article Source Type: research

Biomedical applications of sodium MRI in vivo
In this article we present an up‐to‐date overview of the potential biomedical applications of sodium magnetic resonance imaging (MRI) in vivo. Sodium MRI is a subject of increasing interest in translational imaging research as it can give some direct and quantitative biochemical information on the tissue viability, cell integrity and function, and therefore not only help the diagnosis but also the prognosis of diseases and treatment outcomes. It has already been applied in vivo in most human tissues, such as brain for stroke or tumor detection and therapeutic response, in breast cancer, in articular cartilage, in muscl...
Source: Journal of Magnetic Resonance Imaging - May 30, 2013 Category: Radiology Authors: Guillaume Madelin, Ravinder R. Regatte Tags: Review Source Type: research

Secondhand smoke linked to dementia
Conclusion Secondhand or passive smoking is known to be detrimental to health and has been associated with increased risk of cardiovascular diseases and cancer. However, it is not yet certain whether it is linked to dementia. Though this large study finds a significant link between secondhand smoke exposure and severe dementia syndromes there are several important limitations to be aware of. Problems with measuring dementia diagnoses The method for diagnosis of dementia used by this study was unusual. Though the researchers assessed each individual using a mental state examination, they went on to diagnose them using a com...
Source: NHS News Feed - January 11, 2013 Category: Consumer Health News Tags: Neurology Source Type: news

GMC invests $1.7M in 128-slice CT scanner
Gwinnett Medical Center has invested $1.7 million in a computed tomography (CT) scanner at its Lawrenceville hospital. The 128-slice CT scanner will be used in GMC Lawrenceville's emergency room, which is a Level II trauma center. The CT scanner boasts lower radiation levels than conventional x-ray devices, and allows physicians to see what was previously unseen, a hospital spokeswoman noted. The device will be used for bariatric, cancer, stroke and cardiac patients because it offers 4-D imaging,…
Source: bizjournals.com Health Care:Biotechnology headlines - January 4, 2013 Category: Biotechnology Authors: Urvaksh Karkaria Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function.  >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news