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Total 399 results found since Jan 2013.

Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research

Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study
Lancet Public Health. 2022 Aug 1:S2468-2667(22)00110-4. doi: 10.1016/S2468-2667(22)00110-4. Online ahead of print.ABSTRACTBACKGROUND: The improvement of life expectancy is one of the aims of the Healthy China 2030 blueprint. We aimed to investigate the extent to which healthy lifestyles are associated with life expectancy in Chinese adults.METHODS: We used the prospective China Kadoorie Biobank (CKB) study to examine the relative risk of mortality associated with individual and combined lifestyle factors (never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, an...
Source: Cancer Control - August 4, 2022 Category: Cancer & Oncology Authors: Qiufen Sun Dongmei Yu Junning Fan Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Xiaoming Yang Sam Sansome Yongming Wang Wenhua Zhao Junshi Chen Zhengming Chen Liyun Zhao Jun Lv Liming Li China Kadoorie Biobank Collaborative Group Source Type: research

Association of parental death and illness with offspring suicidal ideation: cross-sectional study in a large cohort of university students
ConclusionsStudents who experienced parental death and common parental illnesses were at risk of reporting suicidal ideation, especially if their family were perceived as an important source of support. As information on parental death or illness can be routinely collected during health visits, attention should be paid to students reporting such experiences.
Source: Social Psychiatry and Psychiatric Epidemiology - July 6, 2022 Category: Psychiatry Source Type: research

Alcohol Consumption and Long-Term Mortality in Men with or without a History of Myocardial Infarction
CONCLUSION: Alcohol consumption of 23-45 g/day was associated with a lower CHD mortality in MI survivors as so in men without MI.PMID:35781275 | DOI:10.5551/jat.63517
Source: Journal of Atherosclerosis and Thrombosis - July 5, 2022 Category: Cardiology Authors: Isao Muraki Hiroyasu Iso Hironori Imano Renzhe Cui Satoyo Ikehara Kazumasa Yamagishi Akiko Tamakoshi Source Type: research

Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review
Crit Rev Food Sci Nutr. 2022 Jun 16:1-66. doi: 10.1080/10408398.2022.2084600. Online ahead of print.ABSTRACTAge-related diseases are associated with increased morbidity in the past few decades and the cost associated with the treatment of these age-related diseases exerts a substantial impact on social and health care expenditure. Anti-aging strategies aim to mitigate, delay and reverse aging-associated diseases, thereby improving quality of life and reducing the burden of age-related pathologies. The natural dietary antioxidant supplementation offers substantial pharmacological and therapeutic effects against various dise...
Source: Atherosclerosis - June 16, 2022 Category: Cardiology Authors: Phaniendra Alugoju V K D Krishna Swamy Naga Venkata Anusha Anthikapalli Tewin Tencomnao Source Type: research

De Novo Sphingolipid Biosynthesis in Atherosclerosis
Adv Exp Med Biol. 2022;1372:31-46. doi: 10.1007/978-981-19-0394-6_3.ABSTRACTAtherosclerosis is the formation of fibrofatty lesions in the arterial wall, and this inflammatory state of the artery is the main cause of advanced pathological processes, including myocardial infarction and stroke. Dyslipidemic conditions with excess cholesterol accumulate within the arterial vessel wall and initiate atherogenic processes. Following vascular reaction and lipid accumulation, the vascular wall gradually thickens. Together with the occurrence of local inflammation, early atherosclerotic lesions lead to advanced pathophysiological ev...
Source: Atherosclerosis - May 3, 2022 Category: Cardiology Authors: Tae-Sik Park Shivani Devi Amitesh Sharma Goon-Tae Kim Kyung-Hee Cho Source Type: research

Prevalence and predictors of hypertension: Evidence from a study of rural India
CONCLUSION: Prevalence of hypertension in the rural population was high and most of the observed predictors were modifiable.PMID:35495805 | PMC:PMC9051678 | DOI:10.4103/jfmpc.jfmpc_967_21
Source: Cancer Control - May 2, 2022 Category: Cancer & Oncology Authors: None Vijna Chandra Pati Mishra Source Type: research

249 The association of comorbidities and survival after out-of-hospital cardiac arrest in Denmark
ConclusionComorbidities significantly influence survival of OHCA patients. Cardiovascular comorbidities constitute the major part of the disease burden. The influence of comorbidity should be included in future treatment guidelines of OHCA patients.Conflict of interestNone.FundingNone.
Source: BMJ Open - May 1, 2022 Category: General Medicine Authors: Sodergren, S., Moller, S., Pedersen, C., Folke, F., Ersboll, A. Tags: Open access Cardiac arrest Source Type: research

'Moderate' alcohol intake could cause peripheral neuropathy warns expert - key risks
THE RAMIFICATIONS of alcohol abuse have been studied at length, with research suggesting there is no healthy level of consumption. There is proof that prolonged drinking is a great cause of cancer, heart disease and stroke. Some lesser-known risks, such as peripheral neuropathy, may result from moderate alcohol intake.
Source: Daily Express - Health - April 30, 2022 Category: Consumer Health News Source Type: news

Fatal Adverse Events of Dabigatran Combined With Aspirin in Elderly Patients: An Analysis Using Data From VigiBase
Conclusion: The fatal adverse events associated with the combined use of dabigatran and aspirin in elderly patients were mainly serious bleeding events, which often occurred within 1 month. Most of these cases had medication errors and most of the patients had multiple diseases, medications, or other conditions at the same time that increase the risk of bleeding. It is suggested that prescription of dabigatran and aspirin in elderly patients should go along with alertness for medication errors, care for correct dose or control of other bleeding risk factors, and the combined medication time should be as short as possible ...
Source: Frontiers in Pharmacology - December 22, 2021 Category: Drugs & Pharmacology Source Type: research