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Total 508 results found since Jan 2013.
Impact of Comorbidities on Lung Cancer Screening Evaluation
CONCLUSION: Patient and procedure-level factors may alter the benefits of lung cancer screening. Data concerning individual risk factors and high-risk complications should therefore be incorporated into diagnostic algorithms to optimize clinical benefit and minimize harm. Further study and validation of the risk factors identified herein are warranted.PMID:35641376 | DOI:10.1016/j.cllc.2022.03.012
Source: Clinical Lung Cancer - May 31, 2022 Category: Cancer & Oncology Authors: Eric M Robinson Benjamin Y Liu Keith Sigel Chung Yin Juan Wisnivesky Minal S Kale Source Type: research
The global burden of disease attributable to ambient fine particulate matter in 204 countries and territories, 1990-2019: A systematic analysis of the Global Burden of Disease Study 2019
Ecotoxicol Environ Saf. 2022 May 4;238:113588. doi: 10.1016/j.ecoenv.2022.113588. Online ahead of print.ABSTRACTUnderstanding the spatio-temporal patterns of the disease burden attributable to ambient PM2.5 across the world is essential for the prevention of related diseases, as well as ambient PM2.5 control. Following the framework and methodology of the Global Burden of Disease Study (GBD) in 2019, the global, regional, and national data on ambient PM2.5-attributable death and disability-adjusted life years (DALYs), and the age-standardized rates of mortality (ASMR) and disability-adjusted life years (ASDR) were summariz...
Source: Cancer Control - May 7, 2022 Category: Cancer & Oncology Authors: Shaowei Sang Chong Chu Tongchao Zhang Hui Chen Xiaorong Yang Source Type: research
Protective Effects and Therapeutics of Ginsenosides for Improving Endothelial Dysfunction: From Therapeutic Potentials, Pharmaceutical Developments to Clinical Trials
Am J Chin Med. 2022;50(3):749-772. doi: 10.1142/S0192415X22500318. Epub 2022 Apr 13.ABSTRACTThe endothelium covers the internal lumen of the entire circulatory system and plays an important modulatory role in vascular homeostasis. Endothelium dysfunction, characterized by a vasoconstrictive, pro-inflammatory, and pro-coagulant state, usually manifests as a significant pathological process of vascular diseases, including hypertension, atherosclerosis (AS), stroke, diabetes mellitus, coronary artery disease, and cancer. Therefore, there is an urgent necessity to seek promising therapeutic drugs or remedies to ameliorate endo...
Source: The American Journal of Chinese Medicine - April 22, 2022 Category: Complementary Medicine Authors: Fang Yang Ming-Yue Yang Jing-Qing Le Bang-Yue Luo Meng-Die Yin None Chao-Li Jia-Li Jiang Yi-Fan Fang Jing-Wei Shao Source Type: research
IJERPH, Vol. 19, Pages 2666: Negative Self-Assessment of Health in Women: Association with Sociodemographic Characteristics, Physical Inactivity and Multimorbidity
Conclusion: The prevalence of NSAH was low. A strong association was found between this variable and multimorbidity. In addition, increased age, low schooling and physical inactivity were predictors of NSAH in women.
Source: International Journal of Environmental Research and Public Health - February 25, 2022 Category: Environmental Health Authors: Thays Ang élica de Pinho Santos Rafael Alves Guimar ães Val éria Pagotto Nat ália Del’ Angelo Aredes Isabela Silva Levindo de Siqueira Suiany Dias Rocha Clarissa Irineu de Sousa Carrijo Claci F átima Weirich Rosso Tags: Article Source Type: research
Heterogeneity of Treatment Effects for Intensive Blood Pressure Therapy by Individual Components of FRS: An Unsupervised Data-Driven Subgroup Analysis in SPRINT and ACCORD
CONCLUSION: Similar findings in patients with hypertensive with T2DM or without diabetes by multivariate subgrouping suggested that the individual components of the FRS could enrich or improve CVD risk assessment. Further research was required to clarify the potential mechanism.PMID:35187120 | PMC:PMC8850629 | DOI:10.3389/fcvm.2022.778756
Source: Cancer Control - February 21, 2022 Category: Cancer & Oncology Authors: Yaqian Wu Jianling Bai Mingzhi Zhang Fang Shao Honggang Yi Dongfang You Yang Zhao Source Type: research
Prospective Comparison of Plasma Biomarker and Traditional Risk Factor Profiles for Incident Isolated Atherosclerotic Disease and Incident Isolated Abdominal Aortic Aneurysm
Conclusions: The data supports the view that components of vascular inflammation and cardiovascular stress drives AAA development, whereas glycated cross-links in abdominal aortic wall tissue may have a plausible role in reducing AAA risk in individuals with DM.PMID:35097031 | PMC:PMC8790118 | DOI:10.3389/fcvm.2021.818656
Source: Atherosclerosis - January 31, 2022 Category: Cardiology Authors: Stefan Acosta Shahab Fatemi Olle Melander Gunnar Engstr öm Anders Gotts äter Source Type: research
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges
Trends Genet. 2022 Jan 27:S0168-9525(22)00005-1. doi: 10.1016/j.tig.2022.01.005. Online ahead of print.ABSTRACTIdentifying etiological risk factors is significant for preventing and treating patients with polycystic ovary syndrome (PCOS). Through genetic variation, Mendelian randomization (MR) assesses causal associations between PCOS risk and related exposure factors. This emerging technology has provided evidence of causal associations of anti-Müllerian hormone (AMH) levels, sex hormone-binding globulin (SHBG) levels, menopause age, adiposity, insulin resistance (IR), depression, breast cancer, ovarian cancer, obsessive...
Source: Trends in Genetics : TIG - January 31, 2022 Category: Genetics & Stem Cells Authors: Congying Wang Wei Wu Haiyan Yang Zhenhong Ye Yue Zhao Jun Liu Liangshan Mu Source Type: research
Prospective Comparison of Plasma Biomarker and Traditional Risk Factor Profiles for Incident Isolated Atherosclerotic Disease and Incident Isolated Abdominal Aortic Aneurysm
Conclusions: The data supports the view that components of vascular inflammation and cardiovascular stress drives AAA development, whereas glycated cross-links in abdominal aortic wall tissue may have a plausible role in reducing AAA risk in individuals with DM.PMID:35097031 | PMC:PMC8790118 | DOI:10.3389/fcvm.2021.818656
Source: Atherosclerosis - January 31, 2022 Category: Cardiology Authors: Stefan Acosta Shahab Fatemi Olle Melander Gunnar Engstr öm Anders Gotts äter Source Type: research
