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Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

Stroke in mitral valve prolapse: risk factors and left atrial function in cryptogenic versus non-cryptogenic ischemic subtypes
ConclusionsMVP-related MR may be protective against stroke despite abnormal LA function. Risk of NC-stroke in MVP is related to common stroke risk factors rather than mitral valve leaflet thickness. The etiology of C-stroke in MVP warrants further studies.
Source: Frontiers in Neurology - July 25, 2023 Category: Neurology Source Type: research

Mind the gap: trajectory of cognitive development in young individuals with sickle cell disease: a cross-sectional study
ConclusionAge-related cognitive trajectories of CYA-SCD may not be impaired but may progress more slowly. Longitudinal studies are required, using tests unaffected by practice. In addition to initiation of medical treatment, including measures to improve arterial oxygen content, early cognitive intervention, educational support, and delivery of extracurricular activities could support cognitive development for CYA-SCD.Graphical Abstract
Source: Frontiers in Neurology - July 25, 2023 Category: Neurology Source Type: research

Editorial: Outcomes of stroke: prediction and improvement
Source: Frontiers in Neurology - July 25, 2023 Category: Neurology Source Type: research

Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists – the RIC-ICH study
ConclusionThese results, based on data from routine clinical practice, suggest that in-hospital mortality after idarucizumab treatment is comparable to that in patients pretreated with VKA. Due to the low precision of estimates, the results must be interpreted with caution.
Source: Frontiers in Neurology - July 24, 2023 Category: Neurology Source Type: research

Combining convolutional attention mechanism and residual deformable Transformer for infarct segmentation from CT scans of acute ischemic stroke patients
ConclusionThe strong correlation between the infarct segmentation obtained via our method and the ground truth allows us to conclude that our method could accurately segment infarcts from NCCT images.
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research

Factors influencing the prognosis of acute basilar artery occlusion patients treated endovascularly: the impact of treatment time window and preoperative symptoms
ConclusionEndovascular intervention for BAO appears to be safe and effective, with greater likelihood of a favorable prognosis in patients treated within ≤6 h. The chances of favorable prognosis could potentially be linked to the severity of the patient's preoperative symptoms.
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research

High posterior cerebral artery flow predicts ischemia recurrence in patients with internal carotid artery occlusion
Recurrent stroke is a dreaded complication of symptomatic internal carotid artery occlusion (ICAO). Transcranial Duplex (TCD)-derived increased flow velocity in the ipsilateral posterior cerebral artery (PCA)-P2 segment indicates activated leptomeningeal collateral recruitment and hemodynamic impairment. Leptomeningeal collaterals are pial vascular connections between the anterior and posterior vascular territories. These secondary collateral routes are activated when primary collaterals via the Circle of Willis are insufficient. Our goal was to test the TCD parameter PCA-P2 flow for prediction of ipsilateral ischemia recu...
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research

Recombination of the right cerebral cortex in patients with left side USN after stroke: fNIRS evidence from resting state
ConclusionThe functional network architecture of the right cerebral cortex exhibits significant topological alterations in individuals with USN following stroke, and the sensitivity index based on the small-world property AUC may be utilized to identify these patients accurately.
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research

Brain network characteristics between subacute and chronic stroke survivors in active, imagery, passive movement task: a pilot study
ConclusionSubacute stroke survivors were characterized by higher transfer efficiency of the entire brain network and weak local nodal effects. Transfer efficiency was reduced, the local nodal role was strengthened, and more neural resources needed to be mobilized to perform motor tasks for chronic survivors. Overall, these results may help to understand the remodeling pattern of the brain network for different post-stroke stages on task conditions and the mechanism of spontaneous recovery.
Source: Frontiers in Neurology - July 19, 2023 Category: Neurology Source Type: research

Comparative study of ultrasonic-guided betamethasone local injection and extracorporeal shock wave therapy in post-stroke hemiplegic shoulder pain: a randomized clinical trial
ConclusionThe ultrasonic-guided betamethasone local injection and extracorporeal shock wave both can improve hemiplegic shoulder pain. However, the UGLI can induce a more cytokine expression level.
Source: Frontiers in Neurology - July 19, 2023 Category: Neurology Source Type: research

Estimation of minimal detectable change in the 10-meter walking test for patients with stroke: a study stratified by gait speed
ConclusionSince the MDC of gait speed and gait time differ depending on the participant’s gait speed, it is necessary to interpret the results according to the participant’s gait speed when judging the effectiveness of therapeutic interventions.
Source: Frontiers in Neurology - July 19, 2023 Category: Neurology Source Type: research

Association between intracranial vessel calcifications, structural brain damage, and cognitive impairment after minor strokes: a prospective study
ConclusionOur findings suggest that the ICCS, which is a simple and readily available imaging marker on NCCT, is associated with brain atrophy, microstructural damage, the extent of SVD, and may predict PSCI. This finding has implications for identifying individuals at risk for PSCI and implementing targeted interventions to mitigate this risk.
Source: Frontiers in Neurology - July 18, 2023 Category: Neurology Source Type: research

Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis
ConclusionsMore research is needed to study health issues in adults with MD. Adults with CP or SB deal with a variety of health issues. More attention for the mental health of these adults is needed. There also is a need for accessible and adequate screening, preventive measures and clinical follow-up.
Source: Frontiers in Neurology - July 18, 2023 Category: Neurology Source Type: research

Identification of a miRNA –mRNA regulatory network for post-stroke depression: a machine-learning approach
ConclusionThe study highlighted gene signatures for PSD with three genes (SPATA2, ZNF208, and YTHDC1) and four upstream miRNAs (miR-6883-5p, miR-6873-3p, miR-4776-3p, and miR-6738-3p). These biomarkers could further our understanding of the pathogenesis of PSD.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research

Feasibility of challenging treadmill speed-dependent gait and perturbation-induced balance training in chronic stroke patients with low ambulation ability: a randomized controlled trial
ConclusionChallenging treadmill speed-dependent gait and treadmill perturbation-induced balance training is feasible and effective to improve ambulation function in chronic stroke patients with low ambulation ability.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research