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Valve-in-valve transcatheter aortic valve implantation versus repeat surgical aortic valve replacement in patients with a failed aortic bioprosthesis
CONCLUSIONS: ViV TAVI was associated with lower in-hospital mortality but higher 30-day and 6-month all-cause readmission. However, there was no difference in risk of in-hospital stroke, post-procedure pacemaker implantation, MACE, and mortality during 30-day and 6-month readmission compared with repeat SAVR, suggesting that ViV TAVI can be performed safely in carefully selected patients.PMID:34521614 | DOI:10.4244/EIJ-D-21-00472
Source: EuroIntervention - September 15, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Monil Majmundar Rajkumar Doshi Ashish Kumar Douglas Johnston James Brockett Anmar Kanaa'N Joseph A Lahorra Lars G Svensson Amar Krishnaswamy Grant W Reed Rishi Puri Samir R Kapadia Ankur Kalra Source Type: research

EP44* Nimbus geometric clot extractor for tough clots - Real world clinical experience and clot composition
ConclusionsNimbus is effective in removing tough clots markedly rich in fibrin and platelets in challenging real world situations.ReferenceJens Fiehler. Failed thrombectomy in acute ischemic stroke: return of the stent? Stroke 2018;49:811–812. https://doi.org/10.1161/STROKEAHA.118.020541DisclosureThis series has emanated from research supported in part by a grant from Science Foundation Ireland (SFI) and the European Regional Development Fund (ERDF) under grant number 13/RC/2073_P2. It is the independent clinical practice of the authors. Cerenovus provided support for post hoc data collection and analysis.
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Nordmeyer, H., Doyle, K., Gralla, J., Phung, T., Molina Gil, S., Belachew, N., Neuhaus, S., Douglas, A., Mordasini, P. Tags: Treatment Source Type: research

EP58 Procedural and functional outcomes for aspiration thrombectomy in acute ischemic stroke patients with differing clot dwell times: A subset analysis from the COMPLETE registry
ConclusionsPatients with longer clot dwell times were associated with more attempts and longer time to achieve reperfusion, more post-procedure complications, and lower likelihood of functional recovery.DisclosureOsama O. Zaidat: Grant/research support from Genentech, Medtronic Neurovascular, Stryker. Consultant for Codman, Medtronic Neurovascular, National Institutes of Health StrokeNet, Penumbra, Stryker. Honoraria from Codman, Medtronic Neurovascular, Penumbra, Stryker. Serves as an expert witness. Ownership interest in Galaxy Therapeutics, Inc. Johanna T. Fifi: Grant/research support: Microvention, Penumbra, Stryker. C...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Zaidat, O., Hassan, A., Abdul Kareem, S., Fifi, J. Tags: Treatment Source Type: research

NODDI highlights recovery mechanisms in white and gray matter in ischemic stroke following human stem cell treatment
CONCLUSIONS: NODDI compliments DTI metrics, enhances interpretation of tissue outcome in ischemic stroke following hMSC application, and may be useful in evaluating or predicting therapeutic response.PMID:34355818 | DOI:10.1002/mrm.28929
Source: Magnetic Resonance in Medicine - August 6, 2021 Category: Radiology Authors: F Andrew Bagdasarian Xuegang Yuan Jacob Athey Bruce A Bunnell Samuel C Grant Source Type: research

Characterizing Intraoperative Vasopressor Use in Total Knee Arthroplasty: A Retrospective Cohort Study
In conclusion, nearly 59% of patients undergoing TKA received intraoperative vasopressor support. History of stroke and older age were significantly associated with increased intraoperative vasopressor use. As the first study to examine vasopressor usage in a TKA patient population, we believe that understanding the association between patient characteristics and intraoperative vasopressor support will help orthopaedic surgeons select the appropriate surgical setting during preoperative optimization. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Ta...
Source: Journal of Knee Surgery - August 4, 2021 Category: Orthopaedics Authors: Lentine, Brandon Vaickus, Max Shewmaker, Grant Niu, Ruijia Son, Sung Jun Mustafa, Wissam Reist, Hailee Smith, Eric L. Tags: Original Article Source Type: research

E-105 Analysis of clinical associations of serum SCFAs taken at the time of thrombectomy in AIS patients
ConclusionsThe evaluation of SCFAs in the serum at the time of stroke provides novel insight into the potential role of SCFAs during stroke in human patients. Age remains a significant factor to SCFA concentrations in stroke patients. The length of time following stroke also contributes to the levels of SCFAs. Previous studies have shown that increased levels of SCFAs is associated with decreased severity of stroke, however our data did not detect any such effect. This observation may be due to the acute time of the blood collection following stroke and analyzing serum instead of fecal samples. Furthermore, acquiring infor...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Henry, N., Frank, J., Fraser, J., Trout, A., Morris, A., Chen, J., Stowe, A., McLouth, C., Pennypacker, K. Tags: Electronic poster abstracts Source Type: research

O-032 Treatment outcomes for ARUBA eligible brain arteriovenous malformations: a comparison of real world data from the NVQI-QOD AVM registry to the ARUBA trial
ConclusionARUBA eligible patients from the NVQI-QOD registry demonstrate a significantly lower risk of stroke or death with intervention of 8.0% (N=174) compared to the 30.7% (N=114) ARUBA trial interventional risk, and is nearly equivalent to the ARUBA trial medical management risk of 10.1% (N=109) over 33 months.Disclosures N. Moore: 1; C; SNIS Joe Niekro Research Grant. R. Abdalla: None. T. Patterson: None. Y. Moazeni: None. P. Rasmussen: 2; C; Blockade Medical, Covidien/Medtronic, Stryker Neurovascular, Perflow Medical. 4; C; Perflow Medical. G. Toth: None. M. Bain: 2; C; Stryker Neurovascular. S. Ansari: None. S. Huss...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Moore, N., Abdalla, R., Patterson, T., Moazeni, Y., Rasmussen, P., Toth, G., Bain, M., Ansari, S., Hussain, S. Tags: Oral abstracts Source Type: research

P-026 Aqua embolic system: evaluating the performance of a new liquid embolic system using a swine AVM model
ConclusionsAES, which is a DMSO free, non-adhesive polysaccharides based LEM, may be used as an embolic material for the treatment of hemorrhagic stroke caused by cerebrovascular diseases, such as brain AVM.A: common carotid artery injection (AP view) shows left ascending pharyngeal artery (APA) and left rete mirabile (red arrow). B: AES is injected from the microcatheter. The AES reflux is reaching the tip of the microcatheter. C: With continuous injection of AES, the microcotheter tip is embedded ¡n the cost of AES. D. Post treatment angiogram shows complete occlusion of the left rete mirabile and APADisclosures I....
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Yuki, I., Ohkawa, K., Li, S., Steward, E., Nguyen, B., Hsu, F., Xu, J., Suzuki, S. Tags: Oral poster abstracts Source Type: research

Disentangling the Psycholinguistic Loci of Anomia with Cognitive Psychometric Models
This article reviews advanced statistical techniques for measuring impairments in object naming, particularly in the context of stroke-induced aphasia. Traditional testing strategies can be challenged by the multifaceted nature of impairments that arise due to the complex relationships between localized brain damage and disruption to the cognitive processes required for successful object naming. Cognitive psychometric models can combine response-type analysis with item-response theory to yield accurate estimates of multiple abilities using data collected from a single task. The models also provide insights about how the te...
Source: Seminars in Speech and Language - July 14, 2021 Category: Speech-Language Pathology Authors: Grant M Walker Source Type: research