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Deep brain stimulation for movement disorders after stroke: a systematic review of the literature
CONCLUSIONS: This is the first systematic review of DBS for poststroke movement disorders. Overall, most studies to date have been case reports and small series reporting heterogeneous patients and surgical strategies. This review suggests that DBS for movement disorders after a stroke has the potential to be effective and safe for diverse patients, and DBS may be a feasible option to improve function even years after a stroke.PMID:36308482 | DOI:10.3171/2022.8.JNS221334
Source: Journal of Neurosurgery - October 29, 2022 Category: Neurosurgery Authors: Mitch R Paro Michal Dyrda Srinath Ramanan Grant Wadman Stacey-Ann Burke Isabella Cipollone Cory Bosworth Sarah Zurek Patrick B Senatus Source Type: research
Neurogenic cardiac outcome in patients after acute ischemic stroke: The brain and heart connection
This study aims to identify the association between cardiac outcomes and middle cerebral artery (MCA) ischemic stroke, with or without insular cortex involvement, as well as the impact of new-onset atrial fibrillation (AF) after AIS on recurrent stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2022 Category: Neurology Authors: Jiangyong Min, Grant Young, Abdullah Umar, Andrew Kampfschulte, Asad Ahrar, Malgorzata Miller, Nadeem Khan, Nabil Wees, Nagib Chalfoun, Muhib Khan Tags: Review Article Source Type: research
Corrigendum to ‘Predictive value of the combination between the intracranial arterial culprit plaque characteristics and the Essen Stroke Risk Score for short-term stroke recurrence’ Journal of Stroke and Cerebrovascular Diseases Volume 31, Issue 9, September 2022, 106624
This study was funded by grants from the Nantong Municipal Science and Technology Plan Project (Nos. MS12020041, MS12021101, HS2019002) and Nantong Municipal Health Commission Youth Project (No. MB2020001).
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2022 Category: Neurology Authors: Kaixuan Ren, Huayun Jiang, Tiantian Li, Chengqun Qian, Shenchu Gong, Tianle Wang, Li Zhu Tags: Corrigendum Source Type: research
Feasibility of Sentinel Cerebral Embolic Protection Device Deployment During Transfemoral Transcatheter Aortic Valve Replacement
Cerebral embolic protection has emerged as a preventive measure for procedural stroke in transcatheter aortic valve replacement (TAVR).1 The Sentinel System (Boston Scientific Corp. Boston, Massachusetts), a 2-filter debris-capturing system, has been the only commercially available protection device in the United States since its approval by the Food and Drug Administration in 2017. In the Sentinel trial, the largest randomized trial (n = 363) so far, the device was successfully deployed in 94.7% of patients.
Source: The American Journal of Cardiology - October 1, 2022 Category: Cardiology Authors: Toshiaki Isogai, Husitha Reddy Vanguru, Amar Krishnaswamy, Ankit Agrawal, Nikolaos Spilias, Shashank Shekhar, Anas M. Saad, Beni Rai Verma, Rishi Puri, Grant W. Reed, Zoran B. Popovi ć, Shinya Unai, James J. Yun, Ken Uchino, Samir R. Kapadia Source Type: research
Brain bioenergetics in chronic hypertension: Risk factor for acute ischemic stroke
Biochem Pharmacol. 2022 Sep 28;205:115260. doi: 10.1016/j.bcp.2022.115260. Online ahead of print.ABSTRACTChronic hypertension is one of the key modifiable risk factors for acute ischemic stroke, also contributing to determine greater neurological deficits and worse functional outcome when an acute cerebrovascular event would occur. A tight relationship exists between cerebrovascular autoregulation, neuronal activity and brain bioenergetics. In chronic hypertension, progressive adaptations of these processes occur as an attempt to cope with the demanding necessity of brain functions, creating a new steady-state homeostatic ...
Source: Biochemical Pharmacology - September 30, 2022 Category: Drugs & Pharmacology Authors: Federica Ferrari Roberto Federico Villa Source Type: research
Brain Bioenergetics in Chronic Hypertension: Risk Factor for Acute Ischemic Stroke
Biochem Pharmacol. 2022 Sep 27:115260. doi: 10.1016/j.bcp.2022.115260. Online ahead of print.ABSTRACTChronic hypertension is one of the key modifiable risk factors for acute ischemic stroke, also contributing to determine greater neurological deficits and worse functional outcome when an acute cerebrovascular event would occur. A tight relationship exists between cerebrovascular autoregulation, neuronal activity and brain bioenergetics. In chronic hypertension, progressive adaptations of these processes occur as an attempt to cope with the demanding necessity of brain functions, creating a new steady-state homeostatic cond...
Source: Biochemical Pharmacology - September 30, 2022 Category: Drugs & Pharmacology Authors: Ferrari Federica Villa Roberto Federico Source Type: research
O19 Late-window aspiration thrombectomy for anterior Acute Ischemic Stroke: subset analysis for COMPLETE Study
ConclusionsLate-window aspiration thrombectomy with Penumbra System is safe and effective for patients with anterior circulation stroke. Our study reports rates of good functional outcome that compare favorably to the DAWN and DEFUSE-3 medical management arms.ReferencesNogueira Rg et al. Dawn Trial Investigators. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 Jan 4;378(1):11–21. DOI: 10.1056/NEJMOA1706442. EPUB 2017 Nov 11. PMID: 29129157.Albers GW et al. Defuse 3 Investigators. Thrombectomy for Stroke at 6 To 16 Hours with Selection by Perfusion Imaging. N Eng...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Hassan, A., Fifi, J., Zaidat, O. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research
O20 Thrombectomy for medium vessel occlusions: treatment effect of successful recanalization on long term functional outcome
ConclusionTICI 2b recanalization in MeVO increased probability of good outcome from 27% to 58%, TICI 3 recanalization did not further improve prognosis. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep and Fabian Flottmann are consultants for Eppdata.Milani Deb-Chatterji has received research grants from the Werner Otto Stiftung.Götz Thomalla received fees as consultant from Acandis, Bayer, and Portola, and fees as lecturer from Acandis, Alexion, Amarin, Bayer, Boehringer-Ingelheim, BristolMyersSquibb, Daiichii Sankyo, Portola, and Stryker.Jens Fiehler received research...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Bechstein, M., Broocks, G., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Meyer, L., Hanning, U., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research
P46 How much of the improvement in functional outcome after successful recanalization is explained by follow-up infarct volume reduction?
Conclusions57% of the improvement of functional outcome after successful recanalization is explained by follow-up infarct volume reduction. Results reflect established pathophysiological assumptions and confirm the value of infarct volume as imaging endpoint in clinical trials.ReferencesBoers AMM, Jansen IGH, Brown S, et al. Mediation of the relationship between endovascular therapy and functional outcome by follow-up infarct volume in patients with acute ischemic stroke. Jama Neurology 2019;76:194–202. DOI: 10.1001/Jamaneurol.2018.3661 Do you have any conflict of interest to declare?: YesConflict of Interest Stateme...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Broocks, G., Austein, F., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Thomalla, G., Hanning, U., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research
P47 Optimal parameter for predicting final Infarct volume and outcome after complete recanalization of medium vessel stroke
ConclusionTMax>10sec volumeon baseline CTP predicts final-infarct-volume and progression as-well-as clinical outcome after MT recanalization for AIS with DMVO.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14.DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research
P62 Continuing early mTICI 2b reperfusion during mechanical thrombectomy is not beneficial for all patients
ConclusionContinuing MT after early mTICI2b might improve functional outcome of the patients who are successfully converted to mTICI2c/3 but an increase in complications due to further retrieval attempts may diminish the potential functional benefit.ReferencesGoyal M, Menon BK, Van Zwam WH, et al. Endovascular Thrombectomy after Large-vessel Ischaemic Stroke: A Meta-analysis of Individual Patient Data from Five Randomised Trials. Lancet. 2016;387(10029):1723–31.Flottmann F, Brekenfeld C, Broocks G, et al. Good Clinical Outcome Decreases with Number of Retrieval Attempts in Stroke Thrombectomy: Beyond the First-Pass E...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Steffen, P., van Horn, N., McDonough, R., Deb-Chatterji, M., Alegiani, A., Thomalla, G., Fiehler, J., Flottmann, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research
