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Vaccination: Swine Flu (H1N1) Vaccine

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Total 733 results found since Jan 2013.

Impact of prior infection and repeated vaccination on post-vaccination antibody titers of the influenza A(H1N1)pdm09 strain in Taiwan schoolchildren: Implications for public health
CONCLUSION: This study supports the implementation of annual mass-vaccination with A(H1N1)pdm09 in schoolchildren for three consecutive influenza seasons when vaccine and circulating strains were well matched, and found that prior infection and pre-vaccination HI-Ab levels positively impacted post-vaccination HI-Ab responses.PMID:35525727 | DOI:10.1016/j.vaccine.2022.03.047
Source: Vaccine - May 7, 2022 Category: Allergy & Immunology Authors: Wei Liu Yu-Hui Lien Ping-Ing Lee Ta-Chien Chan Lih-Chiann Wang Chin-Rur Yang Mei-Shang Ho Juine-Ruey Chen Chia-Chi Ku Chwan-Chuen King Source Type: research

Optimization of A(H1N1)pdm09 vaccine seed viruses: the source of PB1 and HA vRNA as a major determinant for antigen yield
Virus Res. 2022 Apr 30:198795. doi: 10.1016/j.virusres.2022.198795. Online ahead of print.ABSTRACTVaccination prevents and reduces the severity of influenza virus infections. Continuous evolution of influenza hemagglutinin (HA) and neuraminidase (NA) supports the virus to evade pre-existing immunity, which demands vaccines to be reformulated every year. Incorporation of polymerase basic protein 1 (PB1) viral RNA (vRNA) of the same origin of HA and NA vRNA has been observed in previous pandemic viruses and occasionally reported for influenza A vaccine prototype strains of prior seasons. At this point, it remains to be explo...
Source: Virus Research - May 3, 2022 Category: Virology Authors: Filipe Almeida Lu ís A Santos Jo ão M Trigueiro-Louro Helena RebelodeAndrade Source Type: research

Optimization of A(H1N1)pdm09 vaccine seed viruses: The source of PB1 and HA vRNA as a major determinant for antigen yield
Virus Res. 2022 Apr 30;315:198795. doi: 10.1016/j.virusres.2022.198795. Online ahead of print.ABSTRACTVaccination prevents and reduces the severity of influenza virus infections. Continuous evolution of influenza hemagglutinin (HA) and neuraminidase (NA) supports the virus to evade pre-existing immunity, which demands vaccines to be reformulated every year. Incorporation of polymerase basic protein 1 (PB1) viral RNA (vRNA) of the same origin of HA and NA vRNA has been observed in previous pandemic viruses and occasionally reported for influenza A vaccine prototype strains of prior seasons. At this point, it remains to be e...
Source: Virus Research - May 3, 2022 Category: Virology Authors: Filipe Almeida Lu ís A Santos Jo ão M Trigueiro-Louro Helena Rebelo-de-Andrade Source Type: research

Optimization of A(H1N1)pdm09 vaccine seed viruses: the source of PB1 and HA vRNA as a major determinant for antigen yield
Virus Res. 2022 Apr 30:198795. doi: 10.1016/j.virusres.2022.198795. Online ahead of print.ABSTRACTVaccination prevents and reduces the severity of influenza virus infections. Continuous evolution of influenza hemagglutinin (HA) and neuraminidase (NA) supports the virus to evade pre-existing immunity, which demands vaccines to be reformulated every year. Incorporation of polymerase basic protein 1 (PB1) viral RNA (vRNA) of the same origin of HA and NA vRNA has been observed in previous pandemic viruses and occasionally reported for influenza A vaccine prototype strains of prior seasons. At this point, it remains to be explo...
Source: Virus Research - May 3, 2022 Category: Virology Authors: Filipe Almeida Lu ís A Santos Jo ão M Trigueiro-Louro Helena RebelodeAndrade Source Type: research

Optimization of A(H1N1)pdm09 vaccine seed viruses: The source of PB1 and HA vRNA as a major determinant for antigen yield
Virus Res. 2022 Apr 30;315:198795. doi: 10.1016/j.virusres.2022.198795. Online ahead of print.ABSTRACTVaccination prevents and reduces the severity of influenza virus infections. Continuous evolution of influenza hemagglutinin (HA) and neuraminidase (NA) supports the virus to evade pre-existing immunity, which demands vaccines to be reformulated every year. Incorporation of polymerase basic protein 1 (PB1) viral RNA (vRNA) of the same origin of HA and NA vRNA has been observed in previous pandemic viruses and occasionally reported for influenza A vaccine prototype strains of prior seasons. At this point, it remains to be e...
Source: Virus Research - May 3, 2022 Category: Virology Authors: Filipe Almeida Lu ís A Santos Jo ão M Trigueiro-Louro Helena Rebelo-de-Andrade Source Type: research

Modulation of Immune Responses Against HA1 Influenza Vaccine Candidate by B-lymphocyte Stimulator Cytokine in Mice
Iran J Allergy Asthma Immunol. 2022 Apr 11;21(2):207-214. doi: 10.18502/ijaai.v21i2.9228.ABSTRACTUtilizing subunit vaccines is one of the strategies to address influenza infection. Recent innovations have focused on high doses of vaccine antigens and immune enhancers or adjuvant to induce more robust and long-lasting immune responses. Here, an effect of the B cell-activating factor receptor (BAFF-R) to increase the magnitude and durability of immune responses of the recombinant HA1 (rHA1) protein against the H1N1 influenza virus was studied. The HA1 protein and the effector domain of BAFF-R were expressed in the pET-28a (+...
Source: Iranian Journal of Allergy, Asthma and Immunology - May 1, 2022 Category: Allergy & Immunology Authors: Seyedeh Mahsa Bagheri Yazdi Shahla Shahsavandi Fatemeh Fotouhi Majid Tebianian Mohammad Majid Ebrahimi Source Type: research

The determination of haemagglutinin influenza antibodies in the Polish population in the epidemic season 2020/2021 during the SARS-CoV-2 pandemic
Acta Biochim Pol. 2022 Apr 28. doi: 10.18388/abp.2020_6015. Online ahead of print.ABSTRACTThe aim of the study was to prove the level of antibodies against haemagglutinin in the sera of people from seven age groups in the epidemic season 2020/2021 in Poland to determine the differentiation of the antibody level and the protection rate depending on age. The level of anti-haemagglutinin antibodies was established by haemagglutinin inhibition test (HAI). A total of 700 randomly selected sera from people belonging to 7 different age groups were tested. The results confirmed the presence of antibodies against the following infl...
Source: Acta Biochim Pol - April 29, 2022 Category: Biochemistry Authors: Ma łgorzata Niedzielak Ewelina Hallmann Katarzyna Kondratiuk Karol Szyma ński Adam Kolondra Anna Pozna ńska Lidia Brydak Source Type: research