Filtered By:
Specialty: Cancer & Oncology
This page shows you your search results in order of date. This is page number 18.
Order by Relevance | Date
Total 129106 results found since Jan 2013.
Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer
J Transl Med. 2023 Sep 19;21(1):635. doi: 10.1186/s12967-023-04498-5.ABSTRACTA large body of evidence indicates the existence of a complex pathophysiological relationship between cardiovascular diseases and cancer. Mitochondria are crucial organelles whose optimal activity is determined by quality control systems, which regulate critical cellular events, ranging from intermediary metabolism and calcium signaling to mitochondrial dynamics, cell death and mitophagy. Emerging data indicate that impaired mitochondrial quality control drives myocardial dysfunction occurring in several heart diseases, including cardiac hypertrop...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Carmine Rocca Teresa Soda Ernestina Marianna De Francesco Marco Fiorillo Francesco Moccia Giuseppe Viglietto Tommaso Angelone Nicola Amodio Source Type: research
Larval therapy vs conventional silver dressings for full-thickness burns: a randomized controlled trial
CONCLUSIONS: Our findings revealed that MDT has a favorable superiority over conventional regimen for the treatment of grade-III burns, and thus further clinical trials with larger sample size are warranted to confirm these results.PMID:37726738 | DOI:10.1186/s12916-023-03063-7
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Jasem Gaffari Kamran Akbarzadeh Mozhgan Baniardalani Reza Hosseini Safdar Masoumi Zahra Sadat Amiri Razieh Shabani Kordshouli Javad Rafinejad Mostafa Dahmardehei Source Type: research
Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain)
This study identifies an association of long-term exposure to THMs in drinking water, at concentrations below the regulatory thresholds and WHO guidelines, and swimming pool attendance, with chronic lymphocytic leukemia (CLL). These unprecedented findings are highly relevant since CLL is an incurable cancer with still unknown etiology and because the widespread exposure to chlorination by-products that remain in drinking and recreational water worldwide. Despite the demonstrated carcinogenicity in animals of several chlorination by-products, little is known about their potential risks on human health. This study makes a si...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Carolina Donat-Vargas Manolis Kogevinas Yolanda Benavente Laura Costas Elias Campo Gemma Casta ño-Vinyals Guillermo Fernandez-Tardon Javier Llorca In és Gómez-Acebo Nuria Aragon és Marina Pollan Delphine Casabonne Cristina M Villanueva Source Type: research
Analysing potent biomarkers along phytochemicals for breast cancer therapy: an in silico approach
CONCLUSION: The target-ligand complex of green tea active compound Epigallocatechin gallate with NOTCH (1-4) had the potential to become potent anti-breast cancer therapeutic candidates following further research involving wet-lab experiments.PMID:37726449 | DOI:10.1007/s10549-023-07107-7
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Nivruthi Shekar Paton Vuong Parwinder Kaur Source Type: research
Preventive effect of teriparatide on medication-related osteonecrosis of the jaw in rats
In conclusion, TPD administration before tooth extraction helped reduce the occurrence of MRONJ in rats treated with zoledronic acid, confirming its preventative effects.PMID:37726385 | DOI:10.1038/s41598-023-42607-y
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Kyeong-Mee Park Namkwon Lee Jaeyeon Kim Hyun Sil Kim Wonse Park Source Type: research
Effect of functional resistance training on the structure and function of the heart and liver in patients with non-alcoholic fatty liver
Sci Rep. 2023 Sep 19;13(1):15475. doi: 10.1038/s41598-023-42687-w.ABSTRACTThe current study is of the quasi-experimental type, with a pre-and post-test design, and subjects were randomly assigned to one of two groups: control (n = 8) and experimental (test) (n = 8). Based on the patient's self-report and using daily diet control tables, the patient's diet planning percentage of energy supply was managed and controlled for 3 days. The protocol for functional resistance training for these circular exercises, including the squat, lunge, bear crawl, rock press, jumping jack, and back fly lunge, was performed three times per we...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Ramin Jafarikhah Arsalan Damirchi Farhad Rahmani Nia Seyyed Mohammad Taghi Razavi-Toosi Afshin Shafaghi Mostafa Asadian Source Type: research
Endometrial adenocarcinoma recurring in the lung: impact of molecular profile and role of local therapies on prognosis
CONCLUSION: Although few patients will benefit from local treatment (stereotactic body radiation therapy or resection) after a recurrence involving the lung, local therapies might be considered as an option in oligometastatic lung recurrences as they achieve high local control rates and better oncological outcomes than systemic treatment alone.PMID:37726197 | DOI:10.1136/ijgc-2023-004534
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Ana Luzarraga Aznar Vicente Bebia Carlos L ópez-Gil Alexandra Giraldo M P Montoya Ramona Verges Alberto Jauregui Josep Castellvi Assumpci ó Pérez-Benavente Eva Col ás Antonio Gil-Moreno Silvia Cabrera Source Type: research
Effect of invitation letter in language of origin on screening attendance: randomised controlled trial in BreastScreen Norway
CONCLUSIONS: No difference in attendance was observed between immigrant women invited to BreastScreen Norway in their language of origin and in Norwegian compared with Norwegian only. Several barriers to cancer screening may exist among immigrants, and translating the invitation is probably only a part of a complex explanation.TRIAL REGISTRATION: NCT04672265.CLINICALTRIALS: gov NCT04672265.PMID:37726122 | DOI:10.1136/bmj-2023-075465
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Solveig Hofvind Nadia Iqbal Jonas E Thy Gunhild Mangerud Sameer Bhargava Sophia Zackrisson Paula Berstad Source Type: research
A real-world retrospective study to evaluate the reliability of cetuximab plus capecitabine versus capecitabine as maintenance therapy in patients with RAS and BRAF wild-type metastatic colorectal cancer
CONCLUSION: A maintenance therapy using cetuximab plus capecitabine improved survival in patients with metastatic CRC and is well tolerated by patients.PMID:37725905 | DOI:10.1159/000533528
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Jun Li Hang Zhang Xuli Guo Shaoting Dong Yi Li Weizhen Huang Xia Yuan Source Type: research
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
Cell Res. 2023 Sep 19. doi: 10.1038/s41422-023-00874-4. Online ahead of print.ABSTRACTGlycolytic intermediary metabolites such as fructose-1,6-bisphosphate can serve as signals, controlling metabolic states beyond energy metabolism. However, whether glycolytic metabolites also play a role in controlling cell fate remains unexplored. Here, we find that low levels of glycolytic metabolite 3-phosphoglycerate (3-PGA) can switch phosphoglycerate dehydrogenase (PHGDH) from cataplerosis serine synthesis to pro-apoptotic activation of p53. PHGDH is a p53-binding protein, and when unoccupied by 3-PGA interacts with the scaffold pro...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Yu-Qing Wu Chen-Song Zhang Jinye Xiong Dong-Qi Cai Chen-Zhe Wang Yu Wang Yan-Hui Liu Yu Wang Yiming Li Jian Wu Jianfeng Wu Bin Lan Xuefeng Wang Siwei Chen Xianglei Cao Xiaoyan Wei Hui-Hui Hu Huiling Guo Yaxin Yu Abdul Ghafoor Changchuan Xie Yaying Wu Zhen Source Type: research
Induction immunochemotherapy followed by radiotherapy for patients with unresectable locally advanced or metastatic esophageal cancer: A propensity score-matched analysis
CONCLUSION: Induction immunochemotherapy followed by RT might improve locoregional control and survival outcomes for patients with unresectable locally advanced or metastatic esophageal cancer.PMID:37725845 | DOI:10.1016/j.intimp.2023.110955
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Wei Deng Xiao Chang Xin Dong Yuting Zhao Dan Yang Leilei Jiang Anhui Shi Huiming Yu Rong Yu Zefen Xiao Weihu Wang Source Type: research
A 3 mm Port Reduces Postoperative Pain After Laparoscopic Colon Cancer Surgery: A Case-control Matched Study
CONCLUSIONS: The use of 3 mm trocars and instruments in laparoscopic colon cancer surgery can effectively reduce postoperative pain while maintaining perioperative safety.PMID:37725815 | DOI:10.1097/SLE.0000000000001218
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Jin Sun Choi Hyo Jun Kim Han-Ki Lim Min Jung Kim Rumi Shin Ji Won Park Seung-Bum Ryoo Kyu Joo Park Hyeree Park Aesun Shin Seung-Yong Jeong Source Type: research
Proteomic landscape of primary and metastatic brain tumors for heterogeneity discovery
CONCLUSIONS AND CLINICAL RELEVANCE: We characterized an extensive proteomic landscape of BrMs and gliomas. These findings have promising implications for the development of targeted therapies for BrMs and gliomas.PMID:37726528 | DOI:10.1002/prca.202300010
Source: Clinical Colorectal Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Shuang Yang Chengbin Zhou Lei Zhang Yueting Xiong Yongtao Zheng Liuguan Bian Xiaohui Liu Source Type: research
Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-associated Immunity in Lynch Syndrome
CONCLUSIONS: Together these data have important implications for cancer interception in LS, and document for the first-time biological effects of exercise in the immune system of a target organ in patients at-risk for cancer.PMID:37724990 | DOI:10.1158/1078-0432.CCR-23-0088
Source: Clinical Colorectal Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Nan Deng Laura Reyes-Uribe Johannes F Fahrmann Whittney S Thoman Mark F Munsell Jennifer B Dennison Eunice Murage Ranran Wu Ernest T Hawk Selvi Thirumurthi Patrick M Lynch Christina M Dieli-Conwright Alexander J Lazar Sonali Jindal Khoi Chu Manoj Chelvana Source Type: research
Evaluating Prognostic Value of Dynamics of Circulating Lactate Dehydrogenase in Colorectal Cancer Using Modeling and Machine Learning
Clin Pharmacol Ther. 2023 Sep 19. doi: 10.1002/cpt.3052. Online ahead of print.ABSTRACTPre-treatment serum lactate dehydrogenase (LDH) levels have been associated with poor prognosis in several types of cancer, including metastatic colorectal cancer (mCRC). However, very few models link survival to longitudinal LDH measured repeatedly over time during treatment. We investigated the prognostic value of on-treatment LDH dynamics in mCRC. Using data from two large Phase III studies (2L and 3L+ mCRC settings, n = 824 and 210, respectively), we found that integrating longitudinal LDH data with baseline risk factors significantl...
Source: Clinical Colorectal Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Haolun Ding Min Yuan Yaning Yang Manish Gupta Xu Steven Xu Source Type: research
