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Specialty: Cancer & Oncology

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Total 129106 results found since Jan 2013.

Association between ultra-processed food consumption and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies
CONCLUSION: Our results indicate that higher consumption of UPF is slightly related to a higher risk of breast cancer. Further studies in particular of large prospective cohort studies are warranted to confirm these results.PMID:37731393 | PMC:PMC10507475 | DOI:10.3389/fnut.2023.1250361
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Long Shu Xiaoyan Zhang Qin Zhu Xiaoling Lv Caijuan Si Source Type: research

Down-regulation of interleukin-2 predicts poor prognosis and associated with immune escape in lung adenocarcinoma
Conclusion: Our results indicate that down-regulation of IL2 predicts poor prognosis and is associated with immune escape in LUAD, and IL2 could serve as a potential novel prognostic biomarker of LUAD.PMID:37731383 | DOI:10.1177/03946320231202748
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Yongwang Hou Baoli Xiang Zhicong Yang Jiangmin Liu Dandan Xu Lina Geng Minghua Zhan Yuhuan Xu Bin Zhang Source Type: research

Tetrahydrobiopterin from cyanide-degrading bacterium Bacillus pumilus strain SVD06 induces apoptosis in human lung adenocarcinoma cell (A549)
Biotechnol Appl Biochem. 2023 Sep 20. doi: 10.1002/bab.2509. Online ahead of print.ABSTRACTTetrahydrobiopterin (BH4) is an essential biological cofactor and a derivative of pterin which is considered potent anticancer agents. In continuation of our previous study on the identification of BH4 from cyanide-degrading Bacillus pumilus, the present study focuses on evaluating the anticancer properties of BH4 on A549, a human lung adenocarcinoma. Anticancer activity analysis shows that BH4 inhibited A549 cell growth after 24 h of incubation with 0.02 mg/mL. In acridine orange/ethidium bromide staining, BH4-treated A549 cells sho...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Ramasamy Mahendran Sanjay Prasad Selvaraj Anand Raj Dhanapal Sabna Bhaskaran Sarasa Beutline Malgija Mathias Bency Thankappan Daniel Raja Femil Selta Palanivel Naveen Rhenghachar Poorani Navaneethan Sundhar Mamatha M Pillai Rajendran Selvakumar Chih-Yang Source Type: research

Palliative care in colorectal and anal malignancies from diagnosis to death
This article will review the palliative needs of patients diagnosed with CRC and discuss how PC as a specialty is well poised to support these needs.PMID:37731305 | DOI:10.21037/apm-22-1390
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Mohana Karlekar Khaldoun Almhanna Dana Guyer Source Type: research

A randomized trial to evaluate the preventive effect of lafutidine on chemotherapy-induced peripheral neuropathy in patients treated with carboplatin and paclitaxel for lung cancer
CONCLUSIONS: Although the preventive effect of lafutidine on CIPN could not be demonstrated statistically, lafutidine FACT/GOG-Ntx scores showed a trend toward decreased neurotoxicity as chemotherapy proceeded. More reliable studies using lafutidine on the prevention of CIPN should be conducted.TRIAL REGISTRATION: Japan Registry of Clinical Trials identifier: jRCTs021200031.PMID:37731302 | DOI:10.21037/apm-23-90
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Katsuya Cho Hirotaka Saikawa Tatsuya Hashimoto Hiroshi Katagiri Yoshihiro Owada Kazuhiro Yakuwa Itaru Fujimura Yu Utsumi Masachika Akiyama Hiromi Nagashima Fumiaki Takahashi Makoto Maemondo Source Type: research

Randomised controlled trial of Jiandu granule in preventing chemoradiotherapy-induced oral mucositis
CONCLUSION: Jiandu granule reduced the incidence of severe oral mucositis in nasopharyngeal carcinoma patients during concurrent chemoradiotherapy and had an acceptable safety profile.PMID:37731218 | DOI:10.1111/odi.14745
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Huakang Li Jianlong Ke Xiaoyan Wang Bo Xu Qiang Li Ziliang Wu Yue Wang Bing Lin Source Type: research

Oral mucosal disease recognition based on dynamic self-attention and feature discriminant loss
CONCLUSIONS: Convolutional neural networks can effectively capture the visual features of the oral mucosal disease lesions, and the distinguished visual features of different oral lesions can be extracted better using dynamic self-attention and feature discrimination loss function, which is conducive to the auxiliary diagnosis of oral mucosal diseases.PMID:37731172 | DOI:10.1111/odi.14732
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Fei Xie Pengfei Xu Xinyi Xi Xiaokang Gu Panpan Zhang Hexu Wang Xuemin Shen Source Type: research

Automated Reminders Enhance Mailed Fecal Immunochemical Test Completion Among Veterans: a Randomized Controlled Trial
CONCLUSIONS: Automated reminders increased colorectal cancer screening completion among average-risk veterans. An automated phone call or text message was equally effective. VHA facilities seeking to implement a mailed FIT program should consider using phone or text reminders, depending on available resources.PMID:37731137 | DOI:10.1007/s11606-023-08409-8
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Stefanie Deeds Linnaea Schuttner Chelle Wheat Eric Gunnink John Geyer Lauren Beste Anders Chen Jason A Dominitz Karin Nelson Ashok Reddy Source Type: research

A Comparison of the effect of patient-specific vs. weight-based protocols to treat vaso-occlusive episodes (VOE) in the emergency department
CONCLUSIONS: We found a shorter ED length of stay for patients assigned to a PSP. Patients in both groups experienced good pain relief without significant side effects.PMID:37731093 | DOI:10.1111/acem.14805
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Paula Tanabe Stephanie Ibemere Ava E Pierce Caroline E Freiermuth Hayden B Bosworth Hongqui Yang Ifeyinwa Osunkwo James H Paxton John J Strouse Joseph Miller Judith A Paice Padmaja Veeramreddy Patricia L Kavanagh R Gentry Wilkerson Robert Hughes Huiman X Source Type: research

Optimizing process flow diagrams to guide implementation of a colorectal cancer screening intervention in new settings
CONCLUSION: Process maps can potentially support decision-making about the adoption, implementation, and adaptation of existing EBIs in new contexts. Given the complexities involved in deciding whether and how to implement EBIs, these diagrams serve as visual, easily understood tools to inform potential future adopters of the EBI about the activities, resources, and staffing needed for implementation.PMID:37731072 | DOI:10.1007/s10552-023-01769-w
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Meghan C O'Leary Kristen Hassmiller Lich Daniel S Reuland Alison T Brenner Alexis A Moore Shana Ratner Sarah A Birken Stephanie B Wheeler Source Type: research

Role of tissue markers associated with tumor microenvironment in the progression and immune suppression of oral squamous cell carcinoma
Med Oncol. 2023 Sep 20;40(10):303. doi: 10.1007/s12032-023-02169-5.ABSTRACTHead and neck cancers (HNC) continues to dominate major cancers contributing to mortality worldwide. Squamous cell carcinoma is the major type of HNC. Oral Squamous Cell Carcinoma grouped under HNC is a malignant tumor occurring in the oral cavity. The primary risk factors of OSCC are tobacco, alcohol consumption, etc. This review focuses on modulations, mechanisms, growth and differentiation of oral squamous cell carcinoma. Cancer cell surrounds itself with a group of elements forming a favorable environment known as tumor microenvironment (TME). I...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Suganya Ramalingam Sivaramakrishnan Shantha Susruthan Muralitharan Uma Sudhakar Harikrishnan Thamizhchelvan Venkatachalam Deepa Parvathi Source Type: research

Staging of colorectal cancer using lipid biomarkers and machine learning
CONCLUSION: Our findings demonstrate that correlating multiple disease related features with lipid changes could improve CRC prognosis. The identified signatures could be used as reference biomarkers to predict CRC prognosis and classify stages, and monitor therapeutic intervention.PMID:37731020 | DOI:10.1007/s11306-023-02049-z
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sanduru Thamarai Krishnan David Winkler Darren Creek Dovile Anderson Chandra Kirana Guy J Maddern Kevin Fenix Ehud Hauben David Rudd Nicolas Hans Voelcker Source Type: research

Design and synthesis of novel 1,2,3,4-tetrazines as new anti-leukemia cancer agents
Chem Biol Drug Des. 2023 Sep 20. doi: 10.1111/cbdd.14328. Online ahead of print.ABSTRACTA series of novel 1,2,3,4-tetrazines were designed and synthesized. 1 H-NMR spectroscopy, 13 C NMR spectroscopy, and HRMS were used to determine the structures of this novel compounds. Computational approaches suggested that DHFR is a putative target for the newly synthesized 11 compounds. Extensive molecular dynamics simulations followed by molecular docking simulations were employed to evaluate DHFR as a potential target protein. The anticancer activities of the compounds were evaluated against five different types of leukemia cell li...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Oznur Eyilcim Fulya Gunay Omer Tahir Gunkara Yuk Yin Ng Ozlem Ulucan Ihsan Erden Source Type: research

Albendazole induces an anti-tumor effect and potentiates PD-L1 blockade immunotherapy
CONCLUSION: ABZ inhibits melanoma growth and metastasis. Moreover, ABZ synergized with PD-L1 blockade mediates tumor regression.PMID:37730912 | DOI:10.1007/s00432-023-05415-5
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Weinan Zhang Zhiqiang He Fucheng Liang Jie Gong Liuchang Tan Juan Yang Siji Song Luoyingzi Xie Yuangang Lu Source Type: research

Identification of stromal cell-derived factor 4 as a liquid biopsy-based diagnostic marker in solid cancers
In conclusion, serum SDF4 levels could be a promising candidate for a novel diagnostic biomarker for GC and other malignancies.PMID:37730904 | DOI:10.1038/s41598-023-42201-2
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Takahiro Shinozuka Mitsuro Kanda Dai Shimizu Shinichi Umeda Hideki Takami Yoshikuni Inokawa Norifumi Hattori Masamichi Hayashi Chie Tanaka Goro Nakayama Yasuhiro Kodera Source Type: research