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Specialty: Cancer & Oncology
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Total 129106 results found since Jan 2013.
Risk-Directed Ambulatory Thromboprophylaxis in Lung and Gastrointestinal Cancers: The TARGET-TP Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of individuals with lung and gastrointestinal cancers who were stratified by risk score according to thrombosis risk, risk-directed thromboprophylaxis reduced thromboembolism with a desirable number needed to treat, without safety concerns, and with reduced mortality. Individuals at low risk avoided unnecessary intervention. The findings suggest that biomarker-driven, risk-directed primary thromboprophylaxis is an appropriate approach in this population.TRIAL REGISTRATION: ANZCTR Identifier: ACTRN12618000811202.PMID:37733336 | DOI:10.1001/jamaoncol.2023.3634
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Marliese Alexander Sam Harris Craig Underhill Javier Torres Sharad Sharma Nora Lee HuiLi Wong Richard Eek Michael Michael Jeanne Tie Jennifer Rogers Alexander G Heriot David Ball Michael MacManus Rory Wolfe Benjamin J Solomon Kate Burbury Source Type: research
Brain-computer interface relieves chronic chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial
CONCLUSIONS: BCI is a promising treatment for CIPN and may have a longer lasting effect than placebo (nonspecific BCI), which is an important consideration for long-term symptom relief. Although scientifically interesting, the ability to separate real from placebo treatment may not be as important as understanding the placebo effects differently from effects of the intervention.PLAIN LANGUAGE SUMMARY: Chemotherapy-induced nerve pain (neuropathy) can be disabling for cancer survivors; however, the way symptoms are felt depends on how the brain interprets the signals from nerves in the body. We determined that the perception...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sarah Prinsloo Ted J Kaptchuk Dirk De Ridder Randall Lyle Eduardo Bruera Diane Novy Carlos H Barcenas Lorenzo G Cohen Source Type: research
Determinants of physical activity maintenance and the acceptability of a remote coaching intervention following supervised exercise oncology rehabilitation: a qualitative study
CONCLUSIONS: Cancer survivors considered remote coaching acceptable to stimulate PA maintenance following supervised rehabilitation. Interventions should focus on increasing accountability, self-efficacy, forming habits, and helping cancer survivors to overcome barriers.IMPLICATIONS FOR CANCER SURVIVORS: The ability to maintain PA beyond supervised exercise oncology programs depends on many determinants. Remote coaching interventions have potential to target individually relevant determinants following exercise programs in cancer survivors.PMID:37733263 | DOI:10.1007/s11764-023-01455-5
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Anouk T R Weemaes Judith M Sieben Milou Beelen Louisa T M A Mulder Antoine F Lenssen Source Type: research
CD4 levels and NSCLC metastasis: the benefits of maintaining moderate levels
CONCLUSIONS: A threshold effect is shown to exist between the peripheral blood CD4 and distant metastasis in NSCLC patients. It was revealed that the risk of distant metastasis is lower when CD4 is maintained between 32 and 44%, whereas low (< 32%) or high (> 44) levels of CD4 are associated with an increased risk of distant metastasis in NSCLC patients.PMID:37733240 | DOI:10.1007/s00432-023-05418-2
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Ying Bai Yafeng Liu Jing Wu Rui Miao Zhi Xu Chunxiao Hu Jiawei Zhou Jianqiang Guo Jun Xie Zilun Shi Xuansheng Ding Yingru Xing Dong Hu Source Type: research
Transcriptomics Meta-Analysis Reveals Phagosome and Innate Immune System Dysfunction as Potential Mechanisms in the Cortex of Alzheimer's Disease Mouse Strains
J Mol Neurosci. 2023 Sep 21. doi: 10.1007/s12031-023-02152-9. Online ahead of print.ABSTRACTImmune-related pathways can affect the immune system directly, such as the chemokine signaling pathway, or indirectly, such as the phagosome pathway. Alzheimer's disease (AD) is reportedly associated with several immune-related pathways. However, exploring its underlying mechanism is challenging in animal studies because AD mouse strains differentially express immune-related pathway characteristics. To overcome this problem, we performed a meta-analysis to identify significant and consistent immune-related AD pathways that are expre...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Michael Anekson Widjaya Chia-Hsin Liu Shin-Da Lee Wei-Chung Cheng Source Type: research
Compliance with public health recommendations of cancer-free female research volunteers: the French Seintinelles study
CONCLUSIONS: This study allowed to identify the need to increase the level of knowledge on modifiable risk factors for cancer among the general population and to better clarify the content of prevention messages.PMID:37733136 | DOI:10.1007/s10552-023-01788-7
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Alexandra-Cristina Paunescu Cyrille Delpierre Guillemette Jacob Lidia Delrieu Myriam Pannard Marie Pr éau Marina Kvaskoff Source Type: research
Household cooking fuel and gallbladder cancer risk: a multi-centre case-control study in India
CONCLUSION: Biomass burning was associated with a high-risk for GBC and should be considered as a modifiable risk factor for GBC. Clean cooking fuel can potentially mitigate, and a healthy diet can partially reduce the risk among women.PMID:37733135 | DOI:10.1007/s10552-023-01787-8
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Krithiga Shridhar Manigreeva Krishnatreya Ranjit Kumar Dimple Kondal Mouchumee Bhattacharyya Banti Kalita Prakriti Snehil Amulya K Singh Amal Chandra Kataki Ashok Ghosh None D Prabhakaran Poornima Prabhakaran Preet K Dhillon Source Type: research
TikToks Lead to Higher Knowledge and Perceived Severity of Sexual Violence among Adolescent Men
J Youth Adolesc. 2023 Sep 21. doi: 10.1007/s10964-023-01867-7. Online ahead of print.ABSTRACTSocial media communication is a promising way to deliver important health messages about sexual violence to a key population of adolescent men. The researchers conducted an online, between-participants experiment to examine the impact of personal narrative TikToks about sexual violence on adolescent men. Participants were adolescent men (n = 580) aged 15 to 19 (M = 17.3, SD = 1.43). Participants were randomly assigned to treatment (personal narrative TikToks about sexual violence) or control (hair braiding TikTok tutorials) conditi...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sydney Nicolla Allison J Lazard Lucinda L Austin Deen Freelon Heathe Luz McNaughton Reyes Kathryn E Moracco Source Type: research
M < sup > 6 < /sup > A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathway
Discov Oncol. 2023 Sep 21;14(1):175. doi: 10.1007/s12672-023-00786-0.ABSTRACTHuman Hox genes (Homeobox) play a crucial role in embryonic development and cancer. The HOXC10 gene, a member of the HOX family, has been reported abnormally expressed in several cancers. However, the association between HOXC10 and hepatocellular carcinoma (HCC) remains to be elucidated. In the present study, tissue microarray cohort data showed that high levels of HOXC10 expression predicted a poor survival in HCC patients. Meanwhile, HOXC10 was significantly upregulated in the Huh7 cell line compared with the well differentiated cell line HepG2 ...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Miao Li Qianwen Guo Qian Shi Yanzhi Rao Yixin Dong Fangjie Chen Xun Qi Source Type: research
Is triggering receptor expressed on myeloid cell 1 (TREM-1) protein a new marker of serious infectious complications in colorectal surgery?: case-matched pilot study
CONCLUSION: TREM-1 measurements might become a helpful predictive marker in the early diagnosis of serious infectious complications in patients following laparoscopic colorectal surgery.PMID:37733081 | DOI:10.1007/s00423-023-03103-z
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Magdalena Pisarska-Adamczyk Anna Rzepa Maria Kapusta Karolina Zawadzka Beata Ku śnierz-Cabala Micha ł Wysocki Piotr Ma łczak Piotr Major Anna Zub-Pokrowiecka Mateusz Wierdak Micha ł Pędziwiatr Source Type: research
Extended duration of treatment using reduced-frequency dosing of anti-PD-1 therapy in patients with advanced melanoma and Merkel cell carcinoma
CONCLUSIONS: ICI administration at RFD can allow extension of treatment duration, while preserving efficacy and reducing logistical and financial burden. RFD approach deserves further exploration in prospective clinical trials.PMID:37733060 | DOI:10.1007/s00262-023-03539-8
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lisa May Ling Tachiki Daniel S Hippe Karly Williams Silva Evan Thomas Hall William McCamy Dane Fritzsche Andrea Perdue Julia Majovski Thomas Pulliam Daniel A Goldstein Joshua Veatch Joel Ho Paul T Nghiem John A Thompson Shailender Bhatia Source Type: research
Mucormycosis: update on clinical presentation, diagnosis, and treatment
Curr Opin Infect Dis. 2023 Sep 22. doi: 10.1097/QCO.0000000000000976. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Mucormycosis (MCR) is a common opportunistic mold infection, and Mucorales were recently designated by WHO as priority pathogens. The interest in this infection has risen significantly since the major outbreak of MCR in the context of the COVID-19 pandemic, particularly in India. Herein, we summarize recently (last 24 months) published information regarding clinical aspects of MCR.RECENT FINDINGS: The disease remains protean in its clinical presentation, difficult to diagnose, and challenging to treat. In ...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Natalie J M Dailey Garnes Dimitrios P Kontoyiannis Source Type: research
Changes in the proportion of lymphocyte subsets and the expression of surface receptors in peripheral blood of patients with colorectal cancer
Conclusion There are differences in the proportion of NK cell subsets and the expression profile of surface receptors in peripheral blood of patients with colorectal cancer.PMID:37732579
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Yihua Hui Haina Wang Yani Cui Yijun Duan Laifeng Ren Wen Su Source Type: research
Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon diagnosed by molecular pathology: A case report and literature review
CONCLUSION: Based on pathological and genetic analysis, surgery combined with chemotherapy or chemoradiotherapy may have good therapeutic effects for collision tumor.PMID:37731579 | PMC:PMC10507543 | DOI:10.12998/wjcc.v11.i26.6289
Source: Clinical Colorectal Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Meng Jiang Xiao-Ping Yuan Source Type: research
Large colonic lipoma with a laterally spreading tumor treated by endoscopic submucosal dissection: A case report
CONCLUSION: ESD is effective and safe for treating a large colonic lipoma with an LST by minimizing electrical thermal injury.PMID:37731566 | PMC:PMC10507559 | DOI:10.12998/wjcc.v11.i26.6194
Source: Clinical Colorectal Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Jun Yong Bae Hun Kyu Kim Yee Jin Kim Se Woong Kim Youngeun Lee Chang Beom Ryu Moon Sung Lee Source Type: research
