Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain)

This study identifies an association of long-term exposure to THMs in drinking water, at concentrations below the regulatory thresholds and WHO guidelines, and swimming pool attendance, with chronic lymphocytic leukemia (CLL). These unprecedented findings are highly relevant since CLL is an incurable cancer with still unknown etiology and because the widespread exposure to chlorination by-products that remain in drinking and recreational water worldwide. Despite the demonstrated carcinogenicity in animals of several chlorination by-products, little is known about their potential risks on human health. This study makes a significant contribution to the search for environmental factors involved in the etiology of CLL and to the evidence of the health impact of these high prevalent water contaminants.PMID:37726507 | DOI:10.1038/s41370-023-00600-7

Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Carolina Donat-Vargas Manolis Kogevinas Yolanda Benavente Laura Costas Elias Campo Gemma Casta ño-Vinyals Guillermo Fernandez-Tardon Javier Llorca In és Gómez-Acebo Nuria Aragon és Marina Pollan Delphine Casabonne Cristina M Villanueva Source Type: research