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Total 2071 results found since Jan 2013.
Stimulated myotube contractions regulate membrane-bound and soluble TLR4 to prevent LPS-induced signaling and myotube atrophy in skeletal muscle cells
Am J Physiol Cell Physiol. 2023 Jun 19. doi: 10.1152/ajpcell.00007.2023. Online ahead of print.ABSTRACTToll-like receptor 4 (TLR4) activation by lipopolysaccharides (LPS) increases pro-inflammatory cytokine production and upregulation of muscle atrophy signaling pathways. Muscle contractions can suppress LPS/TLR4 axis activation by reducing the protein expression of TLR4 on immune cells. However, the mechanism by which muscle contractions decreases TLR4 remains undefined. Moreover, it is not clear whether muscle contractions affect TLR4 expressed on skeletal muscle cells. The purpose of this study was to uncover the nature...
Source: Am J Physiol Cell Ph... - June 19, 2023 Category: Cytology Authors: Jeremy B Ducharme Zachary James Fennel Zachary J McKenna Roberto Nava Michael R Deyhle Source Type: research
Thermal Responsive Liquid Crystal Elastomer Foam-based Compressible and Omnidirectional Gripper
Chem Asian J. 2023 Jun 16:e202300340. doi: 10.1002/asia.202300340. Online ahead of print.ABSTRACTLiquid crystal elastomers (LCEs) are considered to be a promising material for the fabrication of soft grippers because of their large and reversible deformations, an LCE gripper with suitable compressibility and omnidirectionality has not yet been developed. To overcome these obstacles, this study utilizes salt template method to fabricate a rod-like LCE foam as gripper. The thickness of the compressible foam can be reduced by up to 77%, temporarily maintaining the deformation and enabling the gripper to pass through slits. Th...
Source: Chemistry, an Asian Journal - June 16, 2023 Category: Chemistry Authors: Xinyuhang Zhang Wei Liao Yunpeng Wang Zhongqiang Yang Source Type: research
Effect and formulation of ecolabel policy: A perspective of green supply chain decision and coordination
Environ Sci Pollut Res Int. 2023 Jun 16. doi: 10.1007/s11356-023-28125-4. Online ahead of print.ABSTRACTEcolabel policy has become an important strategy to encourage the consumption of green products throughout the world, contributing to sustainable development which is an inevitable choice for human society. Considering the manufacturer's reputation, consumer's environmental awareness, and effects of ecolabel certification on product demand, this study proposes several Stankelberg game models containing one manufacturer and one retailer to compare the optimal decisions and the impacts on the green supply chain with/withou...
Source: Environmental Science and Pollution Research International - June 16, 2023 Category: Environmental Health Authors: Huan Zhang Qingxin Li Jianli Jiang Source Type: research
Thermal Responsive Liquid Crystal Elastomer Foam-based Compressible and Omnidirectional Gripper
Chem Asian J. 2023 Jun 16:e202300340. doi: 10.1002/asia.202300340. Online ahead of print.ABSTRACTLiquid crystal elastomers (LCEs) are considered to be a promising material for the fabrication of soft grippers because of their large and reversible deformations, an LCE gripper with suitable compressibility and omnidirectionality has not yet been developed. To overcome these obstacles, this study utilizes salt template method to fabricate a rod-like LCE foam as gripper. The thickness of the compressible foam can be reduced by up to 77%, temporarily maintaining the deformation and enabling the gripper to pass through slits. Th...
Source: Chemistry, an Asian Journal - June 16, 2023 Category: Chemistry Authors: Xinyuhang Zhang Wei Liao Yunpeng Wang Zhongqiang Yang Source Type: research
Effect and formulation of ecolabel policy: A perspective of green supply chain decision and coordination
Environ Sci Pollut Res Int. 2023 Jun 16. doi: 10.1007/s11356-023-28125-4. Online ahead of print.ABSTRACTEcolabel policy has become an important strategy to encourage the consumption of green products throughout the world, contributing to sustainable development which is an inevitable choice for human society. Considering the manufacturer's reputation, consumer's environmental awareness, and effects of ecolabel certification on product demand, this study proposes several Stankelberg game models containing one manufacturer and one retailer to compare the optimal decisions and the impacts on the green supply chain with/withou...
Source: Environmental Science and Pollution Research International - June 16, 2023 Category: Environmental Health Authors: Huan Zhang Qingxin Li Jianli Jiang Source Type: research
Could chatbots help devise the next pandemic virus?
Tech experts have been sounding the alarm that artificial intelligence (AI) could turn against humanity by taking over everything from business to warfare. Now, Kevin Esvelt is adding another worry: AI could help somebody with no science background and evil intentions design and order a virus capable of unleashing a pandemic.
Esvelt, a biosecurity expert at the Massachusetts Institute of Technology, recently asked students to create a dangerous virus with the help of ChatGPT or other so-called large language models, systems that can generate humanlike responses to broad questions based on vast training sets of interne...
Source: ScienceNOW - June 14, 2023 Category: Science Source Type: news
Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection
J Zhejiang Univ Sci B. 2023 Jun 15;24(6):539-543. doi: 10.1631/jzus.B2300024.ABSTRACTEpstein-Barr virus (EBV), a double-stranded DNA virus with an envelope, is a ubiquitous pathogen that is prevalent in humans, although most people who contract it do not develop symptoms (Kerr, 2019). While the primary cells EBV attacks are epithelial cells and B lymphocytes, its target range expands to a variety of cell types in immunodeficient hosts. Serological change occurs in 90% of infected patients. Therefore, immunoglobulin M (IgM) and IgG, serologically reactive to viral capsid antigens, are reliable biomarkers for the detection o...
Source: J Zhejiang Univ Sci ... - June 13, 2023 Category: Science Authors: Zhaodi Wang Xuan Lu Yunmei Yang Yuanqiang Lu Source Type: research
