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Nicotine exacerbates diabetic nephropathy through upregulation of Grem1 expression
CONCLUSION: Grem1 plays a vital role in nicotine-exacerbated DN. Grem1 may be a potential therapeutic target for chronic smokers with DN.PMID:37415117 | DOI:10.1186/s10020-023-00692-9
Source: Molecular Medicine - July 6, 2023 Category: Molecular Biology Authors: Jianning Chen Haiting Xiao Rui Xue Vinod Kumar Rukhsana Aslam Syed Faizan Mehdi Huairong Luo Ashwani Malhotra Xiqian Lan Pravin Singhal Source Type: research

Newer therapeutic approaches towards the management of diabetes mellitus: an update.
This article focused on the emerging therapeutic approaches other than the conventional pharmacological therapies, which include stem cell therapy, gene therapy, siRNA, nanotechnology and theranostics. PMID: 31663302 [PubMed - as supplied by publisher]
Source: Panminerva Medica - November 1, 2019 Category: General Medicine Tags: Panminerva Med Source Type: research

Protective Effects of Oxymatrine on Vascular Endothelial Cells from High-Glucose-Induced Cytotoxicity by Inhibiting the Expression of A < sub > 2B < /sub > Receptor
Conclusion: OMT may protect the HUVECs from high glucose-induced cytotoxicity through inhibitting the expression of A2B receptor and inflammatory factors as well as decreasing the phosphorylation of p38 and ERK1/2.Cell Physiol Biochem 2018;45:558 –571
Source: Cellular Physiology and Biochemistry - January 31, 2018 Category: Cytology Source Type: research