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Source: Oncology Letters

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Total 221 results found since Jan 2013.

Upregulation of long non ‑coding RNA LINC00460 in EGFR‑mutant lung cancer indicates a poor prognosis in patients treated with osimertinib
In conclusion, the upregulation of LINC00460, the expression of which is implicated in osimertinib resistance, in the primary site and plasma of patients with EGFR mutation-positive lung cancer may be associated with a poor prognosis in those treated with osimertinib.PMID:37559586 | PMC:PMC10407845 | DOI:10.3892/ol.2023.13966
Source: Oncology Letters - August 10, 2023 Category: Cancer & Oncology Authors: Yuta Nakano Kazutoshi Isobe Takahiro Yoshizawa Naohisa Urabe Sakae Homma Kazuma Kishi Source Type: research

Targeting transient receptor potential canonical 1 reduces non ‑small cell lung cancer chemoresistance and stemness via inhibition of PI3K/AKT signaling
In conclusion, the results of the current study suggested that targeting TRPC1 could attenuate cancer stemness and chemoresistance via suppression of PI3K/AKT signaling in NSCLC.PMID:37153044 | PMC:PMC10157351 | DOI:10.3892/ol.2023.13810
Source: Oncology Letters - May 8, 2023 Category: Cancer & Oncology Authors: Jiahui Jin Xinyu Yan Yaru Zhao Haojie Zhang Kai Zhuang Yating Wen Jingjing He Junzhen Gao Source Type: research

Long non-coding RNA PVT1 promotes the proliferation, migration and EMT process of ovarian cancer cells by regulating CTGF
In conclusion, lncRNA PVT1 promotes the proliferation, migration, invasiveness and EMT process of ovarian cancer cells, and CTGF contributes to the effect of lncRNA PVT1.PMID:36688109 | PMC:PMC9843302 | DOI:10.3892/ol.2022.13657
Source: Oncology Letters - January 23, 2023 Category: Cancer & Oncology Authors: Lingling Dong Huan Wang Yun Gao Shuai Wang Weibo Wang Source Type: research