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Source: American Journal of Translational Research
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Total 412 results found since Jan 2013.
Down-regulation of Jun induces senescence through destabilizing chromatin in osteoarthritis chondrocytes
CONCLUSION: Jun plays a crucial role in OA development and causes senescence by destabilizing chromatin in chondrocytes. These findings provide new insights into OA progression and suggest promising therapeutic targets.PMID:37560235 | PMC:PMC10408544
Source: American Journal of Translational Research - August 10, 2023 Category: Research Authors: Ting Xie Xunshan Ren Huangming Zhuang Fuze Jiang Yuelong Zhang Panghu Zhou Source Type: research
Stat5a promotes < em > Col10a1 < /em > gene expression during chondrocyte hypertrophic differentiation
CONCLUSIONS: Our results support that Stat5a promoted Col10a1 expression and chondrocyte hypertrophic differentiation, possibly via interaction with the 150-bp Col10a1 cis-enhancer.PMID:37434818 | PMC:PMC10331691
Source: American Journal of Translational Research - July 12, 2023 Category: Research Authors: Xuan Wu Chen Chen Tiaotiao Han Huiqin Bian Jinnan Chen Ruoxuan Hei Ye Meng Chenjing Wu Yaojuan Lu Junxia Gu Longwei Qiao Qiping Zheng Source Type: research
