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Source: American Journal of Translational Research

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Total 412 results found since Jan 2013.

Astragaloside IV inhibits the progression of liver cancer by modulating macrophage polarization through the TLR4/NF- κB/STAT3 signaling pathway
CONCLUSION: AS-IV can inhibit the proliferative, invasive, and migratory ability of liver cancer through the suppression of the M2 polarization of macrophages, and the mechanism may involve the TLR4/NF-κB/STAT3 signaling pathway. The present study indicates that AS-IV could be an alternative drug to treat liver cancer, and the polarization of macrophages may be a novel treatment target for HCC.PMID:35422920 | PMC:PMC8991133
Source: American Journal of Translational Research - April 15, 2022 Category: Research Authors: Liang Min Haiqiao Wang Hong Qi Source Type: research

miR-125a-5p-targeted regulation of TRA2 β expression inhibits proliferation and metastasis of hepatocellular carcinoma cells
CONCLUSION: miR-125a-5p inhibits the invasive capacity of HCC cells through targeting the TRA2β pathway.PMID:35035750 | PMC:PMC8748114
Source: American Journal of Translational Research - January 17, 2022 Category: Research Authors: Junde Zhou Linna Wang Yunfu Cui Lanhua Tang Source Type: research