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Source: Pathology Research and Practice
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Total 48 results found since Jan 2013.
Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in Glioma
This study showed that high CCT8 protein expression might be related to poor outcome of glioma, and that CCT8 regulates the proliferation and invasion of glioblastomas.
Source: Pathology Research and Practice - May 19, 2015 Category: Pathology Source Type: research
High expression of vacuolar protein sorting 4B (VPS4B) is associated with accelerated cell proliferation and poor prognosis in human hepatocellular carcinoma
In this study, we investigated the prognostic role of VPS4B in human hepatocellular carcinoma (HCC) and its effect on the growth of HCC cells. Western blot and immunohistochemistrical analyses revealed that VPS4B was significantly upregulated in 98 HCC tissues, compared with adjacent nontumorous samples. Meanwhile, clinicopathological variables and univariate and multivariate survival analyses showed that high VPS4B expression was correlated with multiple clinicopathological factors, including AJCC stage, microvascular invasion, Ki-67 and a poor prognosis. More importantly, univariate and multivariate survival analyses dem...
Source: Pathology Research and Practice - March 2, 2015 Category: Pathology Source Type: research
A low level of GPR37 is associated with human hepatocellular carcinoma progression and poor patient survival
Publication date: December 2014 Source:Pathology - Research and Practice, Volume 210, Issue 12 Author(s): Fang Liu , Changlai Zhu , Xiaodong Huang , Jing Cai , Hua Wang , Xinxiu Wang , Song He , Cheng Liu , Xiaojing Yang , Yixin Zhang , Tianyi Zhang GPR37, also known as parkin-associated endothelin-like receptor (Pael-R), is an orphan G protein-coupled receptor (GPCR). It has been reported that GPCRs play vital roles in the development and progression of cancer. To investigate the potential roles of GPR37 in hepatocellular carcinoma (HCC), expression of GPR37 was examined in human HCC samples. Immunohistochemistry and We...
Source: Pathology Research and Practice - December 2, 2014 Category: Pathology Source Type: research
