Filtered By:
Source: Molecular and Cellular Endocrinology
This page shows you your search results in order of date. This is page number 6.
Order by Relevance | Date
Total 76 results found since Jan 2013.
The circadian clock machinery controls adiponectin expression
In this study, we tested whether the circadian clock helix–loop–helix transcription factors CLOCK and BMAL1 regulate adiponectin expression. We found that adiponectin expression is regulated by the clock through the circadian expression of its transcription factor peroxisome proliferator-activated receptor γ (PPARγ) and its co-activator PPARγ co-activator 1α (PGC1α) in mouse white adipose tissue and differentiated adipocytes. In addition, reconstitution of the core clock mechanism and siRNA experiments in cell culture suggest that the clock directly activates the adiponectin promoter and mediates its expression. I...
Source: Molecular and Cellular Endocrinology - November 3, 2014 Category: Endocrinology Source Type: research
