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Source: World Journal of Gastroenterology : WJG
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Total 125 results found since Jan 2013.
Decreased STAT4 indicates poor prognosis and enhanced cell proliferation in hepatocellular carcinoma.
CONCLUSION: Our data indicate that STAT4 may inhibit HCC development by modulating HCC cell proliferation.
PMID: 25852285 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 7, 2015 Category: Gastroenterology Authors: Wang G, Chen JH, Qiang Y, Wang DZ, Chen Z Tags: World J Gastroenterol Source Type: research
High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma.
CONCLUSION: Our results define an important role of HMGB1 in the progression of cholangiocarcinoma, and HMGB1 may serve as a prognostic marker for IHCC patients.
PMID: 25805932 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - March 21, 2015 Category: Gastroenterology Authors: Xu YF, Ge FJ, Han B, Yang XQ, Su H, Zhao AC, Zhao MH, Yang YB, Yang J Tags: World J Gastroenterol Source Type: research
Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells.
CONCLUSION: These results suggest that claudin 1 is an important messenger that regulates TNF-α-induced gene expression and migration in gastric cancer cells. A deeper understanding of these cellular processes may be helpful in establishing new therapeutic strategies for gastric cancer.
PMID: 25548484 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 21, 2014 Category: Gastroenterology Authors: Shiozaki A, Shimizu H, Ichikawa D, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Iitaka D, Nakashima S, Nako Y, Liu M, Otsuji E Tags: World J Gastroenterol Source Type: research
Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.
CONCLUSION: OPN is a key mediator of the alcohol-induced effects on hepatic stellate cell functions and liver fibrogenesis.
PMID: 25278703 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - September 28, 2014 Category: Gastroenterology Authors: Seth D, Duly A, Kuo PC, McCaughan GW, Haber PS Tags: World J Gastroenterol Source Type: research
CacyBP/SIP nuclear translocation induced by gastrin promotes gastric cancer cell proliferation.
CONCLUSION: CacyBP/SIP nuclear translocation promotes the proliferation and cell cycle progression of gastric cancer cells.
PMID: 25110433 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - August 7, 2014 Category: Gastroenterology Authors: Zhai HH, Meng J, Wang JB, Liu ZX, Li YF, Feng SS Tags: World J Gastroenterol Source Type: research
Inhibition of Girdin enhances chemosensitivity of colorectal cancer cells to oxaliplatin.
CONCLUSION: Girdin knockdown enhances chemosensitivity of colorectal cancer cells to oxaliplatin via TOP2B down-regulation. These findings provide a promising approach to overcome the chemoresistance of colorectal cancer cells.
PMID: 25009397 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - July 7, 2014 Category: Gastroenterology Authors: Zhang YJ, Li AJ, Han Y, Yin L, Lin MB Tags: World J Gastroenterol Source Type: research
Inhibition of autophagy significantly enhances combination therapy with sorafenib and HDAC inhibitors for human hepatoma cells.
CONCLUSION: HDACIs can sensitize HCC cells to sorafenib treatment by regulating the acetylation level of Beclin-1.
PMID: 24833845 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - May 7, 2014 Category: Gastroenterology Authors: Yuan H, Li AJ, Ma SL, Cui LJ, Wu B, Yin L, Wu MC Tags: World J Gastroenterol Source Type: research
Non-transmissible Sendai virus vector encoding c-myc suppressor FBP-interacting repressor for cancer therapy.
CONCLUSION: SeV/dF/FIR showed strong tumor growth suppression with no significant side effects in an animal xenograft model, thus SeV/dF/FIR is potentially applicable for future clinical cancer treatment.
PMID: 24764668 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 21, 2014 Category: Gastroenterology Authors: Matsushita K, Shimada H, Ueda Y, Inoue M, Hasegawa M, Tomonaga T, Matsubara H, Nomura F Tags: World J Gastroenterol Source Type: research
Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: Role of cytokines.
CONCLUSION: To summarize, basal chemokine gene expression for pro-angiogenic chemokines was high in mutated as compared to wild type cell-lines. This reflects the likely existence of a different microenvironment in tumours consistent of wild type or mutated cells. This may help to rationalize the choice of molecular targets for suitable therapeutic investigation in clinical studies.
PMID: 24659889 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - March 21, 2014 Category: Gastroenterology Authors: Khan S, Cameron S, Blaschke M, Moriconi F, Naz N, Amanzada A, Ramadori G, Malik IA Tags: World J Gastroenterol Source Type: research
Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN.
CONCLUSION: Anti-miR-221 can enhance the radiosensitivity of CRC cells by upregulating PTEN.
PMID: 24409057 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 28, 2013 Category: Gastroenterology Authors: Xue Q, Sun K, Deng HJ, Lei ST, Dong JQ, Li GX Tags: World J Gastroenterol Source Type: research
Silencing Bmi-1 enhances the senescence and decreases the metastasis of human gastric cancer cells.
CONCLUSION: Silencing Bmi-1 by RNA interference can increase the senescent cell rate and effectively reduce the metastasis of gastric cancer cells.
PMID: 24379598 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 14, 2013 Category: Gastroenterology Authors: Gao FL, Li WS, Liu CL, Zhao GQ Tags: World J Gastroenterol Source Type: research
Clinicopathological and biological significance of cripto overexpression in human colon cancer.
CONCLUSION: The results provide evidence that cripto siRNA could be an effective approach for the inhibition of cancer cell invasion and migration and thus has potential for use in devising novel preventive and therapeutic strategies for colon cancer metastasis.
PMID: 24379580 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 14, 2013 Category: Gastroenterology Authors: Jiang PC, Zhu L, Fan Y, Zhao HL Tags: World J Gastroenterol Source Type: research
siRNA-targeted inhibition of growth hormone receptor in human colon cancer SW480 cells.
CONCLUSION: Inhibition of GHR in human colon cancer SW480 cells resulted in anti-tumor effects in nude mice.
PMID: 24307807 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 28, 2013 Category: Gastroenterology Authors: Zhou D, Yang J, Huang WD, Wang J, Zhang Q Tags: World J Gastroenterol Source Type: research
PU.1-silenced dendritic cells prolong allograft survival in rats receiving intestinal transplantation.
CONCLUSION: PU.1-silenced semi-mature DCs induced partial immune tolerance both in vitro and in vivo, which could be used as a new strategy to promote transplantation tolerance.
PMID: 24282365 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 21, 2013 Category: Gastroenterology Authors: Xu XW, Ding BW, Zhu CR, Ji W, Li JS Tags: World J Gastroenterol Source Type: research
Interaction between cyclooxygenase-2, Snail, and E-cadherin in gastric cancer cells.
CONCLUSION: COX-2 likely functions upstream of NF-κB and regulates the expression of E-cadherin via NF-κB/Snail signaling pathway in gastric cancer cells.
PMID: 24115825 [PubMed - as supplied by publisher]
Source: World Journal of Gastroenterology : WJG - October 7, 2013 Category: Gastroenterology Authors: Liu XJ, Chen ZF, Li HL, Hu ZN, Liu M, Tian AP, Zhao D, Wu J, Zhou YN, Qiao L Tags: World J Gastroenterol Source Type: research
