Filtered By:
Source: World Journal of Gastroenterology : WJG

This page shows you your search results in order of date. This is page number 7.

Order by Relevance | Date

Total 125 results found since Jan 2013.

Embryonic liver fordin is involved in glucose glycolysis of hepatic stellate cell by regulating PI3K/Akt signaling.
CONCLUSION: ELF is involved in HSC glucose glycolysis by regulating PI3K/Akt signaling. PMID: 27784964 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - October 13, 2016 Category: Gastroenterology Authors: Tu W, Ye J, Wang ZJ Tags: World J Gastroenterol Source Type: research

Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
CONCLUSION: The PI3K/AKT pathway and HIF-1α are both involved in the process of glycolysis in esophageal cancer cells. PMID: 27239113 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - May 27, 2016 Category: Gastroenterology Authors: Zeng L, Zhou HY, Tang NN, Zhang WF, He GJ, Hao B, Feng YD, Zhu H Tags: World J Gastroenterol Source Type: research

Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells.
CONCLUSION: The inverse correlation between miR-125b and cytokine expression after HCV core challenge suggests that miR-125b may negatively regulate HCV-induced immune responses by targeting TLR2/MyD88 signaling in monocytes. PMID: 27158204 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - May 6, 2016 Category: Gastroenterology Authors: Peng C, Wang H, Zhang WJ, Jie SH, Tong QX, Lu MJ, Yang DL Tags: World J Gastroenterol Source Type: research

CacyBP/SIP nuclear translocation regulates p27Kip1 stability in gastric cancer cells.
CONCLUSION: CacyBP/SIP nuclear translocation contributes to the proliferation of GC cells, and CacyBP/SIP exerts this effect, at least in part, by stimulating ubiquitin-mediated degradation of p27Kip1. PMID: 27099442 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 20, 2016 Category: Gastroenterology Authors: Niu YL, Li YJ, Wang JB, Lu YY, Liu ZX, Feng SS, Hu JG, Zhai HH Tags: World J Gastroenterol Source Type: research

Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-κB signaling in colorectal cancer cells.
CONCLUSION: ILK overexpression improved the proliferation, metastasis, and invasion ability of SW480 cells, and this effect may be mediated by the NF-κB signaling pathway. PMID: 27099440 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 20, 2016 Category: Gastroenterology Authors: Shen H, Ma JL, Zhang Y, Deng GL, Qu YL, Wu XL, He JX, Zhang S, Zeng S Tags: World J Gastroenterol Source Type: research

New role and molecular mechanism of Gadd45a in hepatic fibrosis.
CONCLUSION: Gadd45a may counteract hepatic fibrosis by regulating the activation of HSCs via the inhibition of TGF-β/Smad signaling. PMID: 26973416 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - March 7, 2016 Category: Gastroenterology Authors: Hong L, Sun QF, Xu TY, Wu YH, Zhang H, Fu RQ, Cai FJ, Zhou QQ, Zhou K, Du QW, Zhang D, Xu S, Ding JG Tags: World J Gastroenterol Source Type: research

Hypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer.
CONCLUSION: MTH-1 expression in CRC cells was upregulated via HIF-1α in response to hypoxic stress, emphasizing the crucial role of HIF-1α-induced MTH-1 in tumor growth. PMID: 26730155 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 28, 2015 Category: Gastroenterology Authors: Qiu Y, Zheng H, Sun LH, Peng K, Xiao WD, Yang H Tags: World J Gastroenterol Source Type: research

Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA.
CONCLUSION: Knockdown of NF-κB/p65 with siRNA is an effective strategy for inhibiting HepG2 cell growth by downregulating P-gp expression associated chemosensitization and apoptosis induction. PMID: 26668505 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - December 7, 2015 Category: Gastroenterology Authors: Shi Y, Wang SY, Yao M, Sai WL, Wu W, Yang JL, Cai Y, Zheng WJ, Yao DF Tags: World J Gastroenterol Source Type: research

Nanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinoma.
Abstract Hepatocellular carcinoma (HCC) is the 5(th) most common malignancy which is responsible for more than half million annual mortalities; also, it is the third leading cause of cancer related death. Unfavorable systemic side-effects of chemotherapeutic agents and susceptibility to the degradation of small interfering RNAs (siRNAs), which can knock down a specific gene involved in the disease, have hampered their clinical application. So, it could be beneficial to develop an efficient carrier for the stabilization and specific delivery of drugs and siRNA to cells. Targeted nanoparticles have gained considerab...
Source: World Journal of Gastroenterology : WJG - November 14, 2015 Category: Gastroenterology Authors: Varshosaz J, Farzan M Tags: World J Gastroenterol Source Type: research

Effect of fibulin-5 on adhesion, migration and invasion of hepatocellular carcinoma cells via an integrin-dependent mechanism.
CONCLUSION: These results suggest that lower FBLN-5 expression is an important indicator of poor survival and that FBLN-5 inhibits HCC motility via an integrin-dependent mechanism. RGD-dependent suppression of MMP-7 by FBLN-5 might contribute to the development of new therapeutic strategies for HCC. PMID: 26494967 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - October 21, 2015 Category: Gastroenterology Authors: Tang JC, Liu JH, Liu XL, Liang X, Cai XJ Tags: World J Gastroenterol Source Type: research

Macrophage migration inhibitory factor as a potential prognostic factor in gastric cancer.
CONCLUSION: MIF could be of prognostic value in gastric cancer and might be a potential target for small-molecule therapy. PMID: 26379396 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - September 14, 2015 Category: Gastroenterology Authors: He LJ, Xie D, Hu PJ, Liao YJ, Deng HX, Kung HF, Zhu SL Tags: World J Gastroenterol Source Type: research

Notch1 downregulation combined with interleukin-24 inhibits invasion and migration of hepatocellular carcinoma cells.
CONCLUSION: Down-regulation of Notch1 by GSI-I or siRNA combined with IL-24 can sensitize apoptosis and decrease the invasion and migration capabilities of HepG2 cells. PMID: 26361419 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - September 7, 2015 Category: Gastroenterology Authors: Han B, Liu SH, Guo WD, Zhang B, Wang JP, Cao YK, Liu J Tags: World J Gastroenterol Source Type: research

Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma.
CONCLUSION: Linc00675 may function as an oncogene during PDAC development, and its expression is an independent predictor of unfavorable prognosis in patients with PDAC. PMID: 26309360 [PubMed - as supplied by publisher]
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Li DD, Fu ZQ, Lin Q, Zhou Y, Zhou QB, Li ZH, Tan LP, Chen RF, Liu YM Tags: World J Gastroenterol Source Type: research

Therapeutic potential of small interfering RNAs/micro interfering RNA in hepatocellular carcinoma.
Abstract Hepatocellular carcinoma (HCC) is the predominant form of primary liver cancer and represents the third leading cause of cancer-related death worldwide. Current available therapeutic approaches are poorly effective, especially for the advanced forms of the disease. In the last year, short double stranded RNA molecules termed small interfering RNAs (siRNAs) and micro interfering RNAs (miRNA), emerged as interesting molecules with potential therapeutic value for HCC. The practical use of these molecules is however limited by the identification of optimal molecular targets and especially by the lack of effec...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Farra R, Grassi M, Grassi G, Dapas B Tags: World J Gastroenterol Source Type: research

Overexpression of pim-3 and protective role in lipopolysaccharide-stimulated hepatic stellate cells.
CONCLUSION: Overexpression of pim-3 plays a protective role in LPS-stimulated HSC-T6 cells. PMID: 26269675 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - August 7, 2015 Category: Gastroenterology Authors: Liu LH, Lai QN, Chen JY, Zhang JX, Cheng B Tags: World J Gastroenterol Source Type: research