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Source: Journal of Cellular Biochemistry
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Total 134 results found since Jan 2013.
Metformin inhibits tumorigenesis in HBV ‐induced hepatocellular carcinoma by suppressing HULC overexpression caused by HBX
Conclusion: This study indicated that metformin imposed inhibitory effect on the HBV‐associated HCC by negatively regulating the HULC /p18/miR‐200a/ZEB1 signaling pathway. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 12, 2017 Category: Biochemistry Authors: Zhen Jiang, Haichao Liu Tags: Article Source Type: research
Molecular Mechanisms of Tributyltin ‐Induced Alterations in Cholesterol Homeostasis and Steroidogenesis in Hamster Testis: In Vivo and In Vitro Studies
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 12, 2017 Category: Biochemistry Authors: Kanimozhi V, Palanivel K, Akbarsha MA, Kadalmani B Tags: Article Source Type: research
NGAL gene silencing inhibits proliferation and promotes apoptosis of human gastric cancer cells: an in vivo and in vitro study
This study aims to explore effects of neutrophil gelatinase‐associated lipocalin (NGAL) gene silencing on the proliferation and apoptosis of human gastric cancer MGC‐803 and SGC‐7901 cells. NGAL‐siRNA was designed, synthesized and randomly divided into NGAL‐siRNA and control‐siRNA groups. Gastric cancer cells MGC‐803 and SGC‐7901 were grouped into blank, NGAL‐OE, and control‐OE groups. Expression of NGAL and apoptosis‐related proteins were detected by qRT‐PCR and Western blotting. Cell cycle and apoptosis were tested by flow cytometry, and cell proliferation by water soluble tetrazolium‐1 (WST‐1...
Source: Journal of Cellular Biochemistry - December 11, 2017 Category: Biochemistry Authors: Ming ‐Yang Han, Jie‐Wei Nie, Yuan‐Yuan Li, Yuan‐Zeng Zhu, Gang Wu Tags: Article Source Type: research
Long non ‐coding RNA cox‐2 prevents immune evasion and metastasis of hepatocellular carcinoma by altering M1/M2 macrophage polarization
Conclusion: These findings indicate that lncRNA cox‐2 inhibits HCC immune evasion and tumor growth by inhibiting the polarization of M2 macrophages. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - November 13, 2017 Category: Biochemistry Authors: Yibiao Ye, Yunxiuxiu Xu, Yu Lai, Wenguang He, Yanshan Li, Ruomei Wang, Xinxi Luo, Xinxi Luo, Rufu Chen, Tao Chen Tags: Article Source Type: research
MicroRNA ‐329 inhibits cell proliferation and tumor growth while facilitates apoptosis via negative regulation of KDM1A in gastric cancer
Conclusion: We conclude that miRNA‐329 functions as a tumor suppressor in GC, which could be achieved via transcriptional suppression of KDM1A. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - November 11, 2017 Category: Biochemistry Authors: Lisheng Cai, Qiuxian Chen, Shunyong Fang, Mingqiao Lian, Mingzhi Cai Tags: Article Source Type: research
HOXA3 promotes tumor growth of human colon cancer through activating EGFR/Ras/Raf/MEK/ERK signaling pathway
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - October 26, 2017 Category: Biochemistry Authors: Xianxiang Zhang, Guangwei Liu, Lei Ding, Tao Jiang, Shihong Shao, Yuan Gao, Yun Lu Tags: Article Source Type: research
SENP1/HIF ‐1α feedback loop modulates hypoxia‐induced cell proliferation, invasion, and EMT in human osteosarcoma cells
Hypoxia is an element intrinsic to most solid‐tumor microenvironments, including that of osteosarcoma (OS), and is associated with resistance to therapy, poor survival, and a malignant phenotype. The purpose of the present study was to investigate the role and underlying mechanism of SUMO‐specific protease 1 (SENP1)/hypoxia‐inducible factor‐1α (HIF‐1α) feedback loop in hypoxic microenvironment of OS. We observed that the expression of SENP1 was remarkably upregulated in OS cells. Additionally, there was a concomitant high expression of HIF‐1α and SENP1 in MG‐63 cells under a hypoxic microenvironment. Inter...
Source: Journal of Cellular Biochemistry - September 27, 2017 Category: Biochemistry Authors: Xiaowei Wang, Xiaoju Liang, Huan Liang, Bing Wang Tags: RESEARCH ARTICLE Source Type: research
MicroRNA ‐410 Is Involved in Mitophagy after Cardiac Ischemia/Reperfusion Injury by Targeting High‐mobility group box 1 protein
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - September 15, 2017 Category: Biochemistry Authors: Fan Yang, Tong Li, Zhihuan Dong, Rui Mi Tags: Article Source Type: research
SIRT1 deacetylates KLF4 to activate Claudin ‐5 transcription in ovarian cancer cells
In conclusion, our data suggest that SIRT1 activates CLDN5 transcription by deacetylating and potentiating KLF4. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - September 9, 2017 Category: Biochemistry Authors: Xinjian Zhang, Junliang Chen, Lina Sun, Yong Xu Tags: Article Source Type: research
Leptin Induces Matrix Metalloproteinase 7 Expression To Promote Ovarian Cancer Cell Invasion By Activating ERK And JNK Pathways
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - September 8, 2017 Category: Biochemistry Authors: Ahmad Ghasemi, Seyed Isaac Hashemy, Mahmoud Aghaei, Mojtaba Panjehpour Tags: Article Source Type: research
MiR ‐200a mediates protection of thymosin beta 4 in cardiac microvascular endothelial cells as a novel mechanism under hypoxia‐reoxygenation injury
In conclusion, our results determined that Tβ4 attenuated H/R induced CMECs injury by miR‐200a‐Nrf2 signaling. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - August 31, 2017 Category: Biochemistry Authors: Yang Li, Xiaolong Zhu, Xiping Liu, Aolin Du, Bo Yu Tags: Article Source Type: research
Suppression of c ‐Myc enhances p21WAF1/CIP1‐mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - August 18, 2017 Category: Biochemistry Authors: Yun ‐Jeong Jeong, Hyang‐Sook Hoe, Hyun‐Ji Cho, Kwan‐Kyu Park, Dae‐Dong Kim, Cheorl‐Ho Kim, Junji Magae, Dong Wook Kang, Sang‐Rae Lee, Young‐Chae Chang Tags: Article Source Type: research
Hypoxia ‐induced microRNA‐26b inhibition contributes to hypoxic pulmonary hypertension via CTGF
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - August 17, 2017 Category: Biochemistry Authors: Sijing Zhou, Li Sun, Chao Cao, Peipei Wu, Min Li, Gengyun Sun, Guanghe Fei, Xing Ding, Ran Wang Tags: Article Source Type: research
LincRNA DYN ‐LRB2‐2 upregulates cholesterol efflux by decreasing TLR2 expression in macrophages
Conclusion: LincRNA DYN‐LRB2‐2 upregulates cholesterol efflux by decreasing TLR2 expression in macrophages. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - August 16, 2017 Category: Biochemistry Authors: Yongqiang Li, Shuxin Shen, Shoukun Ding, Lixia Wang Tags: Article Source Type: research
Effects of long noncoding RNA SPRY4 ‐IT1‐mediated EZH2 on the invasion and migration of lung adenocarcinoma
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - August 10, 2017 Category: Biochemistry Authors: Xin Wen, Xin ‐Rui Han, Yong‐Jian Wang, Shao‐Hua Fan, Juan Zhuang, Zi‐Feng Zhang, Qun Shan, Meng‐Qiu Li, Bin Hu, Chun‐Hui Sun, Qiao Wu, Jun‐Hua Tan, Dong‐Mei Wu, Jun Lu, Yuan‐Lin Zheng Tags: Article Source Type: research
